Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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1980studies shown
Showing 126-150 of 1,980
RecruitingNCT03887715

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

This study is looking at whether a digital support tool can help people with Treatment Resistant Depression. Participants take part in a digital support tool and complete follow-up assessments.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
LivaNova
Condition
Depression
RecruitingNCT06005103

A Randomized Clinical Trial Comparing Active Versus Sham T-PEMF Headband Treatment for Depression

This study is comparing Treatment with MoodHeadBand (T-PEMF treatment) with placebo for people with Moderate Depression, Severe Depressive Episode Without Psychotic Symptoms, Recurrent depression, Current Episode Moderate, or Recurrent depression, Current Episode Severe Without Psychotic Symptoms. Participants receive Treatment with MoodHeadBand (T-PEMF treatment) or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 65 Years
Countries
Denmark
Sponsor
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Condition
Depression
RecruitingNCT06072898

A Randomized Neuroimaging Trial of Psilocybin in Depression

This study is comparing Psilocybin with placebo for people with depression. Participants receive Psilocybin or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 64 Years
Countries
Canada
Sponsor
Sunnybrook Health Sciences Centre
Condition
Depression
RecruitingNCT06906939

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

This study is looking at whether a digital support tool can help people with Knee Osteoarthritis or Depression. Participants take part in a digital support tool and complete follow-up assessments.

DepressionOtherFrom 50 Years to 95 Years
Countries
United States
Sponsor
University of California, Los Angeles
Condition
Depression
RecruitingNCT07412756

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

This study is comparing Brenipatide with placebo for people with major depression. Participants receive Brenipatide or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 75 Years
Countries
Australia, Brazil, Canada, China, Germany, Greece, Japan, Mexico, Poland, United States, South Korea, Spain, Taiwan, United Kingdom
Sponsor
Eli Lilly and Company
Condition
Depression
RecruitingNCT07053345

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

This study is looking at evaluate how well esketamine nasal spray works in improving depressive symptoms in participants with treatment resistant depression (TRD) for people with depression, Treatment-Resistant. Taking part may give some people access to Esketamine 56 mg, but direct benefit is not guaranteed.

DepressionOtherFrom 18 Years to 64 Years
Countries
South Korea
Sponsor
Janssen Korea, Ltd., Korea
Condition
Depression
RecruitingNCT06793397

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

This study is testing whether CYB003, compared with placebo, is safe and helpful as an add-on treatment for people with depression. Participants receive CYB003 or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 85 Years
Countries
Australia, Czech Republic, Germany, Greece, Ireland, Poland, United Kingdom, United States
Sponsor
Cybin IRL Limited
Condition
Depression
RecruitingNCT07186309

A Study of a Test for Postpartum Depression at Home

This observational study is following people with Postpartum Depression or Pregnancy to understand outcomes over time. Participants mainly provide questionnaire, assessment, or follow-up information rather than receiving a new study treatment.

DepressionDeviceOver 18 Years
Countries
United States
Sponsor
University of Virginia
Condition
Depression
RecruitingNCT06524830

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

This observational study is following people with Treatment Resistant Depression to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.

DepressionOtherFrom 18 Years to 65 Years
Countries
Australia, Canada, United Kingdom, United States
Sponsor
atai Therapeutics, Inc.
Condition
Depression
RecruitingNCT07258485

A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)

This observational study is following people with major depression to understand outcomes over time. Participants are followed over time so researchers can learn from clinical and follow-up information.

DepressionOtherFrom 18 Years to 74 Years
Countries
United States
Sponsor
Janssen Research & Development, LLC
Condition
Depression
RecruitingNCT07065240

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

This study is looking at whether SPT-300 can help people with depression or depression With Anxious Distress. Participants take part in SPT-300 and complete follow-up assessments.

DepressionOtherFrom 18 Years to 65 Years
Countries
Bulgaria, Czech Republic, Germany, Poland, Slovakia, United States
Sponsor
Seaport Therapeutics
Condition
Depression
RecruitingNCT07193901

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Characteristics of (R)-Ketamine Hydrochloride Nasal Spray in Patients With Depression and Acute Suicidal Ideation or Behavior

This study is comparing Low Dose PRT042 nasal spray with placebo for people with depression (depression. Participants receive Low Dose PRT042 nasal spray or placebo and complete study visits and assessments.

DepressionOtherFrom 18 Years to 64 Years
Countries
China
Sponsor
Sichuan Purity Pharmaceutical Technology Co., Ltd.
Condition
Depression
RecruitingNCT07196501

A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

This study is looking at care and outcomes for people with depression. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.

DepressionOtherOver 18 Years
Countries
Australia, Bulgaria, Canada, Estonia, Italy, Poland, Serbia, South Korea, Spain, Taiwan, United States
Sponsor
Neurocrine Biosciences
Condition
Depression