Transmucosal Buprenorphine for Moderate to Severe Opioid-use Disorder
This study is completed in the United States and in Canada. It is testing transmucosal Buprenorphine for Moderate to Severe Opioid-use Disorder.
Addiction, Moderate to Severe Opioid-use DisorderDrugOver 18 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Then choose your country and confirm availability with each study site.
In plain English
Key information made simple
What is this study testing?
This study is testing whether Transmucosal Buprenorphine may be useful for adults experiencing addiction.
What would participation involve?
Participants may receive Transmucosal Buprenorphine, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Canada and in the United States.
Who is it mainly for?
This study appears to be mainly for adults with addiction.
What should you check before joining?
Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.
Your next step
Check the study details
Check the official source, then confirm these points with the research team.
Where are visits, can any be remote, and how much time is needed?
Costs and support
What costs, reimbursement or compensation apply?
Before joining
Questions to ask before joining
What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?
Study clarity
Things to check before joining
Study start dateStarted: October 26, 2021
Recruitment status
Completed
Enrollment listed in the registry
785
Sponsor
Indivior Inc.
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 4Usually happens after approval, to monitor real-world use, safety, and longer-term outcomes.
Locations
United States, Canada
Age range
Over 18 Years
Official registry ID
NCT04995029
Official title
A Randomised, Double-Blind Study Comparing 2 Maintenance Dosing Regimens of Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in Treatment-Seeking Adult Participants With Opioid Use Disorder and High-risk Opioid Use
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT04995029. We help you review the study, but cannot decide medical eligibility.
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Canada · 1 site
Centre for Addiction and Mental Health
Toronto, Ontario
Site status: Not listed — confirm with the team
United States · 28 sites
Collaborative Neuroscience Network, LLC
Garden Grove, California
Site status: Not listed — confirm with the team
Asclepes Research Centers
Panorama City, California
Site status: Not listed — confirm with the team
Artemis Institute for Clinical Research
San Diego, California
Site status: Not listed — confirm with the team
Bay Pines VA Healthcare System
Bay Pines, Florida
Site status: Not listed — confirm with the team
Sarkis Clinical Trials
Gainesville, Florida
Site status: Not listed — confirm with the team
Accel Research Sites- Lakeland Clinical Research Unit
Lakeland, Florida
Site status: Not listed — confirm with the team
Behavioral Clinical Research, Inc
Miami Lakes, Florida
Site status: Not listed — confirm with the team
Innovative Clinical Research Inc.
North Miami, Florida
Site status: Not listed — confirm with the team
Clinical Neuroscience Solutions, Inc
Orlando, Florida
Site status: Not listed — confirm with the team
Brigham and Women's Hospital
Boston, Massachusetts
Site status: Not listed — confirm with the team
Hassman Research Institute
Berlin, New Jersey
Site status: Not listed — confirm with the team
Center For Emotional Fitness
Cherry Hill, New Jersey
Site status: Not listed — confirm with the team
ICAHN School of Medicine at Mount Sinai
New York, New York
Site status: Not listed — confirm with the team
Duke Hospital
Durham, North Carolina
Site status: Not listed — confirm with the team
Monroe Biomedical Research
Monroe, North Carolina
Site status: Not listed — confirm with the team
Midwest Clinical Research
Dayton, Ohio
Site status: Not listed — confirm with the team
Pahl Pharmaceutical Professionals LLC
Oklahoma City, Oklahoma
Site status: Not listed — confirm with the team
SP Research, PLLC
Oklahoma City, Oklahoma
Site status: Not listed — confirm with the team
Unity Clinical Research
Oklahoma City, Oklahoma
Site status: Not listed — confirm with the team
Today Clinical Research
Oklahoma City, Oklahoma
Site status: Not listed — confirm with the team
Clinical Research Associates of Central PA
Altoona, Pennsylvania
Site status: Not listed — confirm with the team
Carolina Medical Research, LLC
Clinton, South Carolina
Site status: Not listed — confirm with the team
Prisma Health ITOR Research Pharmacy
Greenville, South Carolina
Site status: Not listed — confirm with the team
Carolina Medical Research, LLC
Greenville, South Carolina
Site status: Not listed — confirm with the team
David Weitzman
Myrtle Beach, South Carolina
Site status: Not listed — confirm with the team
Insite Clinical Research
DeSoto, Texas
Site status: Not listed — confirm with the team
Progressive Clinical Research
Bountiful, Utah
Site status: Not listed — confirm with the team
Alpine Research Organization
Clinton, Utah
Site status: Not listed — confirm with the team
In practice
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Important
Not medical advice
Information from public sources.
Are you the study sponsor? Contact us to update this page: hi@hopestage.com
FAQ
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with addiction. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving Transmucosal Buprenorphine, Extended-release Buprenorphine. Phase 4 studies usually happen after treatment approval, to monitor real-world use.
Are there criteria about substance use or wanting to reduce it?
The public registry appears to mention tobacco, nicotine, alcohol, cannabis, or another addiction-related topic. Ask the study team whether you need to want to stop, reduce, already be abstinent, or simply meet use-related criteria. Eligibility must be confirmed by the study team.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Indivior Inc., which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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