CompletedNCT05571878

Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents

This study is completed. It focuses on depression and currently lists study information in Canada.

DepressionOtherFrom 14 Years to 18 Years

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Study reference: NCT05571878. HopeStage can help you review the study, but cannot decide medical eligibility.

In plain English

Key information made simple

This study is comparing Humalog with placebo for people with depression. Participants receive Humalog or placebo and complete study visits and assessments. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.

What to expect

Your next step

The official record suggests in-person participation through a lab, with sites including Centre for Addiction and Mental Health in Toronto. Participation appears to involve assessments along with scans or samples to help researchers understand patterns more clearly. The main fit is usually matching the main diagnosis and meeting the main study requirements, while common reasons not to take part include active substance or alcohol problems that could affect the results and pregnancy or breastfeeding. The official record does not list a formal phase, which usually means this is focused more on feasibility, delivery, or support than a standard drug-development stage.

Before joining

Questions to ask before joining

What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?

Study clarity

Things to check before joining

Study start dateStarted: September 1, 2021

Time commitment: multiple visits or assessments
Study phase: Not available
Enrollment: Not available
Recruitment status: Completed
Sponsor: Centre for Addiction and Mental Health
Sponsor type: Hospital / academic medical center
Main activity: medication or study treatment
Intervention: Not available
Source: Official registry link

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Public study data

Key study information

Official title: Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
Condition: Depression
Study status: Completed
Sponsor / lead affiliation: Centre for Addiction and Mental Health
Location / country: Canada
Registry: ClinicalTrials.gov
External trial ID: NCT05571878

Why this study may matter

This study may matter because it adds public evidence around depression. HopeStage presents it as a starting point for understanding the study, checking the official source, and preparing questions with a care team.

In practice

For you

Taking part may help clarify how this condition is measured or understood.

It requires regular visits and structured follow-up.

Requires travel, with in-person participation in Canada.

Official source

Registry reference

This page links back to the public source record so people can verify details directly with the registry and research team.

If you want the full study description, eligibility criteria, locations, and sponsor information in the original format, this is the place to check before taking the next step.

Official title: Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
Source: ClinicalTrials.gov
Official registry link: Open official registry
External trial ID: NCT05571878

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. It includes a comparison with placebo. Direct benefit is not guaranteed.

Who is behind this study, and what type of sponsor is it?

This study is sponsored by Centre for Addiction and Mental Health, a hospital or academic medical center. The Centre for Addiction and Mental Health is a mental health hospital and research center. The sponsor is based in Canada. Sponsor website: https://www.camh.ca. You can verify the sponsor and study responsibility in the official registry record.

What does participation involve, what phase is it, and what should I ask about safety?

This study may involve medication or study treatment, study visits, and assessments. The time commitment is multiple visits or assessments. The study phase is not available in HopeStage data. Check the official source record to see whether a phase is listed. Enrollment is not available in HopeStage data. HopeStage cannot say whether a study is safe or right for you. Before joining, ask the research team about possible risks, time commitment, visits, side effects, compensation, safety monitoring, and whether participation may affect your current care.

Where can I verify the study details?

Use the official source record linked on this page to check the full study description, recruitment status, eligibility criteria, locations, sponsor information, phase, enrollment, contact details, and any listed risks or requirements.

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