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TerminatedNCT06029439

Effectiveness of NMRA-335140 in depression

This study was terminated in the United States, in France, in Canada, .... It is testing NMRA-335140 for depression.

DepressionDrugFrom 18 Years to 65 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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In plain English

Key information made simple

What is this study testing?

This study is testing whether NMRA-335140 may be useful for adults experiencing depression.

What would participation involve?

Participants may receive NMRA-335140, attend study visits with the research team. The registry lists locations in Brazil, in Bulgaria, and in Canada.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)

  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: November 10, 2023
Recruitment status
Terminated
Enrollment listed in the registry
904
Sponsor
Neumora Therapeutics, Inc.
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, France, Canada, ...
Age range
From 18 Years to 65 Years
Official registry ID
NCT06029439
Official title
Long-term Study to Assess the Safety and Effectiveness of NMRA-335140 in Participants With Major Depressive Disorder

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Study ID: NCT06029439. We help you review the study, but cannot decide medical eligibility.

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Brazil · 7 sites
  • Neumora Investigator Site
    Curitiba, Paraná
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Botafogo - Rio de Janeiro, Rio de Janeiro
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Porto Alegre, Rio Grande do Sul
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Santa Cecília, São Paulo
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    São Bernardo do Campo, São Paulo
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    São José do Rio Preto, São Paulo
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    São Paulo
    Site status: Not listed — confirm with the team
Bulgaria · 8 sites
  • Neumora Investigator Site
    Cherven Bryag, Pleven
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Varosha, Targovishte
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Kardzhali
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Pleven
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Varna
    Site status: Not listed — confirm with the team
Canada · 5 sites
  • Neumora Investigator Site
    Kelowna, British Columbia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hamilton, Ontario
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Markham, Ontario
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Mississauga, Ontario
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Toronto, Ontario
    Site status: Not listed — confirm with the team
Chile · 5 sites
  • Neumora Investigator Site
    Santiago, Santiago Metropolitan
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Santiago, Santiago Metropolitan
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Santiago, Santiago Metropolitan
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Santiago, Santiago Metropolitan
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Antofagasta
    Site status: Not listed — confirm with the team
Czechia · 5 sites
  • Neumora Investigator Site
    Pilsen, Plzeň
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Prague, Prague
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Kladno, South Bohemian
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Kladno
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Prague
    Site status: Not listed — confirm with the team
Finland · 3 sites
  • Neumora Investigator Site
    Helsinki, Etelä-Suomen Lääni
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Turku, Etelä-Suomen Lääni
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Oulu, Oulun Lääni
    Site status: Not listed — confirm with the team
France · 5 sites
  • Neumora Investigator Site
    Clermont-Ferrand, Auvergne-Rhône-Alpes
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Douai, Hauts-de-France
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Montpellier, Hérault
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    La Roche-sur-Yon, Vendée
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Poitiers, Vienne
    Site status: Not listed — confirm with the team
Germany · 5 sites
  • Neumora Investigator Site #1
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hamburg
    Site status: Not listed — confirm with the team
Poland · 7 sites
  • Neumora Investigator Site
    Suchy Las, Greater Poland Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Bydgoszcz, Kuyavian-Pomeranian Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Wroclaw, Lower Silesian Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Lublin, Lublin Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Lublin, Lublin Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Białystok, Podkarpackie Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Gdansk, Pomeranian Voivodeship
    Site status: Not listed — confirm with the team
Sweden · 2 sites
  • Neumora Investigator Site
    Lund, Skåne County
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Stockholm, Stolkholm Ian
    Site status: Not listed — confirm with the team
United States · 126 sites
  • Neumora Investigator site
    Huntsville, Alabama
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Phoenix, Arizona
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Bentonville, Arkansas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Rogers, Arkansas
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Bellflower, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Cerritos, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Encino, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Garden Grove, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Glendale, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Imperial, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Irvine, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Lafayette, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Long Beach, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Long Beach, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Newport Beach, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Oceanside, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Orange, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Orange, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Riverside, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    San Diego, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    San Francisco, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    San Jose, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Santa Ana, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sherman Oaks, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Temecula, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Torrance, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Colorado Springs, Colorado
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New Haven, Connecticut
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Norwalk, Connecticut
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Bradenton, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Brandon, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Gainesville, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hallandale, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hollywood, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Jacksonville, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Lauderhill, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Maitland, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami Beach, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #2
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami Springs, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Pembroke Pines, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Pompano Beach, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Pompano Beach, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Saint Augustine, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Marietta, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Savannah, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Warrenville, Illinois
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Marrero, Louisiana
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New Orleans, Louisiana
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Baltimore, Maryland
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Towson, Maryland
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Boston, Massachusetts
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Boston, Massachusetts
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Methuen, Massachusetts
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Springfield, Massachusetts
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Watertown, Massachusetts
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Bloomfield Township, Michigan
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Mankato, Minnesota
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Flowood, Mississippi
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Saint Charles, Missouri
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Las Vegas, Nevada
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin, New Jersey
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Princeton, New Jersey
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Toms River, New Jersey
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Albuquerque, New Mexico
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Brooklyn, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Buffalo, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Cedarhurst, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Inwood, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New York, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New York, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New York, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    The Bronx, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Charlotte, North Carolina
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Monroe, North Carolina
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Columbus, Ohio
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Dayton, Ohio
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    North Canton, Ohio
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Edmond, Oklahoma
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Oklahoma City, Oklahoma
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Allentown, Pennsylvania
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Media, Pennsylvania
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Philadelphia, Pennsylvania
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Memphis, Tennessee
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Austin, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Austin, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Dallas, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    DeSoto, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Fort Worth, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Wichita Falls, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Bellevue, Washington
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Everett, Washington
    Site status: Not listed — confirm with the team
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving NMRA-335140. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 65 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Neumora Therapeutics, Inc., which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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TerminatedNCT05169710

Investigational Drug for depression

This study was terminated in the United States, in Canada, in Bulgaria, .... It is testing investigational Drug for depression.