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CompletedNCT06058039

Study Effects of Oral NMRA-335140 Versus Placebo in people with Major Depressive Disorder

This study is completed in the United States, in France, in Bulgaria, .... It is testing Effects of Oral NMRA-335140 for depression.

DepressionDrugFrom 18 Years to 65 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

Then choose your country and confirm availability with each study site.

In plain English

Key information made simple

What is this study testing?

This study is testing whether NMRA-335140 may be useful for adults experiencing depression.

What would participation involve?

Participants may receive NMRA-335140, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Bulgaria, in Czechia, and in Finland.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: December 21, 2023
Recruitment status
Completed
Enrollment listed in the registry
422
Sponsor
Neumora Therapeutics, Inc.
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, France, Bulgaria, ...
Age range
From 18 Years to 65 Years
Official registry ID
NCT06058039
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Bulgaria · 9 sites
  • Neumora Investigator Site
    Cherven Bryag, Pleven
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Kardzhali
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Pleven
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Targovishte
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Varna
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Varna
    Site status: Not listed — confirm with the team
Czechia · 5 sites
  • Neumora Investigator Site
    Pilsen, Plzen
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Prague, Prague
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site #1
    Kladno, South Bohemian
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Kladno
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Prague
    Site status: Not listed — confirm with the team
Finland · 3 sites
  • Neumora Investigator Site
    Helsinki, Etelä-Suomen Lääni
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Turku, Etelä-Suomen Lääni
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Oulu, Oulun Lääni
    Site status: Not listed — confirm with the team
France · 6 sites
  • Neumora Investigator Site
    Clermont-Ferrand, Auvergne-Rhône-Alpes
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Douai, Hauts-de-France
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Montpellier, Hérault
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Angers, Maine-et-Loire
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    La Roche-sur-Yon, Vendée
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Poitiers, Vienne
    Site status: Not listed — confirm with the team
Germany · 5 sites
  • Neumora Investigator Site #1
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hamburg
    Site status: Not listed — confirm with the team
Poland · 7 sites
  • Neumora Investigator Site
    Suchy Las, Greater Poland Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Bydgoszcz, Kuyavian-Pomeranian Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Wroclaw, Lower Silesian Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Lublin, Lublin Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Lublin, Lublin Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Bialystok, Podlaskie Voivodeship
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Gdansk, Pomeranian Voivodeship
    Site status: Not listed — confirm with the team
Sweden · 2 sites
  • Neumora Investigator Site
    Lund, Skåne County
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Stockholm, Stockholm County
    Site status: Not listed — confirm with the team
United States · 34 sites
  • Neumora Investigator Site
    Cerritos, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Irvine, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Long Beach, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    San Diego, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    San Francisco, California
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New Haven, Connecticut
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Brandon, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Jacksonville, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Miami Beach, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator site
    Miami Springs, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Palm Bay, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Pembroke Pines, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Pompano Beach, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Saint Augustine, Florida
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Savannah, Georgia
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Springfield, Massachusetts
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Omaha, Nebraska
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Berlin, New Jersey
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New York, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    New York, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Charlotte, North Carolina
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Austin, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    DeSoto, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Fort Worth, Texas
    Site status: Not listed — confirm with the team
  • Neumora Investigator Site
    Plano, Texas
    Site status: Not listed — confirm with the team
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving NMRA-335140, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 65 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Neumora Therapeutics, Inc., which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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