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Active Not RecruitingNCT06433635

Sequential Multiple Assignment Randomized Trial for Depression in bipolarity

This study is active but not recruiting. It focuses on bipolarity and currently lists study information in the United States and Canada.

BipolarityDrugFrom 18 Years to 75 Years
In plain English

Key information made simple

This study is looking at whether a digital support tool can help people with Bipolarity I or Depression. Participants receive a study treatment and complete follow-up visits and assessments. Taking part may give some people access to a digital support tool, but direct benefit is not guaranteed.

What to expect

Your next step

The official record suggests in-person participation through a hospital, with sites including University of Alabama Birmingham, Steve Strakowski in Bloomington, and John Hopkins in Baltimore. Participation appears to involve using a digital tool or support program and giving feedback through check-ins or assessments. The main fit is usually matching the main diagnosis and meeting the main study requirements, while common reasons not to take part include active substance or alcohol problems that could affect the results and safety concerns that need urgent care first. This is a later-stage study, which usually means the approach is being followed in broader real-world use.

Public study data

Key study information

Official title
Sequential Multiple Assignment Randomized Trial for Bipolar Depression
Condition
Bipolar I Disorder; Depression
Study status
Active Not Recruiting
Phase
Phase 4
Sponsor / lead affiliation
Massachusetts General Hospital
Intervention
Cariprazine, Aripiprazole/Escitalopram combination, Quetiapine, Lurasidone
Location / country
United States, Canada
Registry
ClinicalTrials.gov
Why this study may matter

Why this study may matter

This study may matter because it is evaluating Cariprazine, Aripiprazole/Escitalopram combination, Quetiapine, Lurasidone in a structured research setting. For people exploring bipolarity research, clear information about the goal, status, contacts, and official source can support better questions before any decision.

Before joining

Questions to ask before joining

Official source

Registry reference

This page links back to the public source record so people can verify details directly with the registry and research team.

If you want the full study description, eligibility criteria, locations, and sponsor information in the original format, this is the place to check before taking the next step.

Open source record
Need help deciding?

Ask HopeStage to review this study with me

This form records your interest so HopeStage can follow up with practical guidance. It is not a medical eligibility decision and it does not guarantee a study spot.

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In practice

For you

Taking part may give access to a new approach being evaluated.

It requires regular visits and structured follow-up.

Requires travel, with in-person participation in United States.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

Study clarity

Things to check before joining

Sponsor
Massachusetts General Hospital
Sponsor type
Hospital / academic medical center
Main activity
digital app or tool
Intervention
Cariprazine, Aripiprazole/Escitalopram combination, Quetiapine, Lurasidone
Time commitment
long follow-up or multiple visits
Study phase
Phase 4
Enrollment
Not available
Recruitment status
Active Not Recruiting
Source
Official registry link
FAQ

Questions about this study

What is Sequential Multiple Assignment Randomized Trial for Depression in bipolarity?

This study is exploring digital app or tool for people with bipolarity. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed.

Who is behind this study, and what type of sponsor is it?

This study is sponsored by Massachusetts General Hospital, a hospital or academic medical center. This sponsor is a hospital or academic medical center involved in clinical care and research. The sponsor is based in the United States. Sponsor website: https://www.massgeneralbrigham.org. You can verify the sponsor and study responsibility in the official registry record.

What does participation involve, what phase is it, and what should I ask about safety?

This study may involve digital app or tool, study visits, and assessments. The time commitment is long follow-up or multiple visits. The study phase is Phase 4. Earlier-phase studies are often more focused on safety, dose, or feasibility, while later-phase studies usually involve more participants and more information about the intervention. The official source record gives the most accurate details. Enrollment is not available in HopeStage data. HopeStage cannot say whether a study is safe or right for you. Before joining, ask the research team about possible risks, time commitment, visits, side effects, compensation, safety monitoring, and whether participation may affect your current care.

Where can I verify the study details?

Use the official source record linked on this page to check the full study description, recruitment status, eligibility criteria, locations, sponsor information, phase, enrollment, contact details, and any listed risks or requirements.

Sequential Multiple Assignment Randomized Trial. — Bipolarity Clinical Trial | HopeStage