Then choose your country and confirm availability with each study site.
In plain English
Key information made simple
What is this study testing?
This study is testing whether CYB003 may be useful for adults experiencing depression.
What would participation involve?
Participants may receive CYB003, attend study visits with the research team. The registry lists locations in Australia and in the United States.
Who is it mainly for?
This study appears to be mainly for adults with depression.
What should you check before joining?
Ask about the dose, safety monitoring, and possible side effects, whether there is a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.
Your next step
Check the study details
Check the official source, then confirm these points with the research team.
Where are visits, can any be remote, and how much time is needed?
Costs and support
What costs, reimbursement or compensation apply?
Before joining
Questions to ask before joining
What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?
Study clarity
Things to check before joining
Study start dateStarted: July 18, 2025
Recruitment status
Enrolling By Invitation
Enrollment listed in the registry
468
Sponsor
Cybin IRL Limited
Sponsor type
Unknown or unclear
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, Australia
Age range
From 18 Years to 85 Years
Official registry ID
NCT06605105
Official title
A Phase III Long-Term Extension Trial With Optional Additional Doses of CYB003 to Assess the Safety and Long-term Efficacy in Participants With Major Depressive Disorder (EXTEND)
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT06605105. We help you review the study, but cannot decide medical eligibility.
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Australia · 5 sites
Sydney Local Health District
Camperdown, New South Wales
Site status: Not listed — confirm with the team
Thompson Brain & Mind Healthcare
Maroochydore, Queensland
Site status: Not listed — confirm with the team
Neurocentrix Research
Carlton, Victoria
Site status: Not listed — confirm with the team
Ramsay Clinic
Melbourne, Victoria
Site status: Not listed — confirm with the team
Monash University - Notting Hill
Notting Hill, Victoria
Site status: Not listed — confirm with the team
United States · 28 sites
Combined Research Orlando
Phoenix, Arizona
Site status: Not listed — confirm with the team
Open Mind Collective / UCSF Medical Center - Mount Zion
San Francisco, California
Site status: Not listed — confirm with the team
Inland Psychiatric Medical Group Inc (IPMG Research)
San Juan Capistrano, California
Site status: Not listed — confirm with the team
Mountain View Clinical Research
Denver, Colorado
Site status: Not listed — confirm with the team
Starlight Clinical Research
Evergreen, Colorado
Site status: Not listed — confirm with the team
Research Centers of America
Hollywood, Florida
Site status: Not listed — confirm with the team
K2 Medical Research
Lady Lake, Florida
Site status: Not listed — confirm with the team
Segal Trials Center for Psychedelic Research
Lauderhill, Florida
Site status: Not listed — confirm with the team
K2 Medical Research
Maitland, Florida
Site status: Not listed — confirm with the team
Clinical Neuroscience Solutions, Inc
Orlando, Florida
Site status: Not listed — confirm with the team
Charter Research
Orlando, Florida
Site status: Not listed — confirm with the team
Cenexel iResearcvh Atlanta, LLC
Atlanta, Georgia
Site status: Not listed — confirm with the team
Atlanta Center For Medical Research
Atlanta, Georgia
Site status: Not listed — confirm with the team
CenExel iResearch
Savannah, Georgia
Site status: Not listed — confirm with the team
Uptown Research Institute
Chicago, Illinois
Site status: Not listed — confirm with the team
Psychiatric Medicine Associates, LLC
Skokie, Illinois
Site status: Not listed — confirm with the team
Psychiatric Medicine Associates
Skokie, Illinois
Site status: Not listed — confirm with the team
Sunstone Medical, PC
Rockville, Maryland
Site status: Not listed — confirm with the team
Adams Clinical Boston
Boston, Massachusetts
Site status: Not listed — confirm with the team
Adams Clinical
Watertown, Massachusetts
Site status: Not listed — confirm with the team
Redbird Research
Las Vegas, Nevada
Site status: Not listed — confirm with the team
Adams Clinical Harlem
New York, New York
Site status: Not listed — confirm with the team
Adams Clinical Bronx
The Bronx, New York
Site status: Not listed — confirm with the team
Neurobehavioral Clinical Research
Canton, Ohio
Site status: Not listed — confirm with the team
Clinical Neuroscience Solutions, CNS Healthcare
Memphis, Tennessee
Site status: Not listed — confirm with the team
InSite Clinical Research, LLC
DeSoto, Texas
Site status: Not listed — confirm with the team
Zillan Clinical Research
Houston, Texas
Site status: Not listed — confirm with the team
Cedar Clinical Research
Draper, Utah
Site status: Not listed — confirm with the team
In practice
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Important
Not medical advice
Information from public sources.
Are you the study sponsor? Contact us to update this page: hi@hopestage.com
FAQ
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving CYB003. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 85 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Cybin IRL Limited, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists enrollment by invitation. This is not open recruitment; contact the research team to understand who may be invited.
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