Enrolling By InvitationNCT06605105

Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

This study is enrolling by invitation. It focuses on depression and currently lists participation information in the United States.

DepressionOtherFrom 18 Years to 85 Years

In plain English

Key information made simple

This study is looking at care and outcomes for people with depression. Taking part may give some people access to a digital support tool, but direct benefit is not guaranteed.

What to expect

Your next step

The official record suggests in-person participation through a clinic, with sites including Combined Research Orlando in Phoenix, Open Mind Collective / UCSF Medical Center - Mount Zion in San Francisco, and Mountain View Clinical Research in Denver. Participation appears to involve using a digital tool or support program and giving feedback through check-ins or assessments. The main fit is usually being able to understand the study and consent and having a stable enough treatment background for the study, while common reasons not to take part include safety concerns that need urgent care first and active substance or alcohol problems that could affect the results. This is a later-stage study, which usually means a larger group and a closer look at how well the approach holds up.

Public study data

Key study information

Condition: Major Depressive Disorder
Study status: Enrolling By Invitation
Sponsor / lead affiliation: Cybin IRL Limited
Location / country: United States
Registry: ClinicalTrials.gov

Why this study may matter

This study may matter because it adds public evidence around depression. HopeStage presents it as a starting point for understanding the study, checking the official source, and preparing questions with a care team.

Before joining

Questions to ask before joining

What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?

Official source

Registry reference

This page links back to the public source record so people can verify details directly with the registry and research team.

If you want the full study description, eligibility criteria, locations, and sponsor information in the original format, this is the place to check before taking the next step.

Open source record

Need help deciding?

Ask HopeStage to review this study with me

This form records your interest so HopeStage can follow up with practical guidance. It is not a medical eligibility decision and it does not guarantee a study spot.

Study reference: NCT06605105. We only ask for your email here. HopeStage can help you review the study, but this is not a medical eligibility decision.

In practice

For you

Taking part may help clarify how this condition is measured or understood.

It requires regular visits and structured follow-up.

Requires travel, with in-person participation in United States.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

Study clarity

Things to check before joining

Sponsor: Cybin IRL Limited
Sponsor type: Unknown or unclear
Main activity: digital app or tool
Intervention: Not available
Time commitment: long follow-up or multiple visits
Study phase: Not available
Enrollment: Not available
Recruitment status: Enrolling By Invitation
Source: Official registry link

FAQ

Questions about this study

What is Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)?

This study is exploring digital app or tool for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed.

Who is behind this study, and what type of sponsor is it?

This study is sponsored by Cybin IRL Limited. We could not clearly classify the sponsor type from the available data. Check the official source record to verify who is responsible for the study.

What does participation involve, what phase is it, and what should I ask about safety?

This study may involve digital app or tool, study visits, and assessments. The time commitment is long follow-up or multiple visits. The study phase is not available in HopeStage data. Check the official source record to see whether a phase is listed. Enrollment is not available in HopeStage data. HopeStage cannot say whether a study is safe or right for you. Before joining, ask the research team about possible risks, time commitment, visits, side effects, compensation, safety monitoring, and whether participation may affect your current care.

Where can I verify the study details?

Use the official source record linked on this page to check the full study description, recruitment status, eligibility criteria, locations, sponsor information, phase, enrollment, contact details, and any listed risks or requirements.