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Tailored weight-management care for people with bipolarity

About this title

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

Read the official source — NCT07213466

Researchers study whether patterns of appetite and metabolism can guide the choice of weight-loss medicines for adults with obesity and bipolarity. Participants receive a medicine selected for their obesity profile, while researchers assess the approach’s feasibility and effects.

Medication studyAges 18–65United States
The study in practice

Understand this study

What is this study about?

Researchers study whether patterns of appetite and metabolism can guide the choice of weight-loss medicines for adults with obesity and bipolarity. Participants receive a medicine selected for their obesity profile, while researchers assess the approach’s feasibility and effects.

Who could participate?

This study is for people with bipolarity. Listed age limits: 18 years to 65 years. Other eligibility criteria apply.

Listed locations
RochesterSee all locations and recruitment
Study phase
Phase 4Usually happens after approval, to monitor real-world use, safety, and longer-term outcomes.

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What to know before participating

A point to clarify

This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?

Study clarity

Things to check before joining

Study start dateStarted: January 19, 2026
Recruitment status
Recruiting
Enrollment listed in the registry
100
Sponsor
Mayo Clinic
Sponsor type
Hospital / academic medical center
Study type
Drug
Intervention type
Psychotherapy / behavioral intervention, Medication / drug
Study phase
Phase 4Usually happens after approval, to monitor real-world use, safety, and longer-term outcomes.
Locations
United States
Age range
From 18 Years to 65 Years
Official registry ID
NCT07213466
Official title
Show the full official title

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder - OBOE-Mayo

Recruitment & locations

Currently recruiting

Rochester

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FAQ

Questions about this study

What is this study about?

Researchers study whether patterns of appetite and metabolism can guide the choice of weight-loss medicines for adults with obesity and bipolarity. Participants receive a medicine selected for their obesity profile, while researchers assess the approach’s feasibility and effects.

Who is behind this study?

The study sponsor is Mayo Clinic, a hospital or academic medical center.

Does this study involve medication?

Yes. The study involves medication, including semaglutide, Phentermine-Topiramate and naltrexone and bupropion (combination).

Who can participate?

This study is for people with bipolarity. Listed age limits: 18 years to 65 years. Other eligibility criteria apply.

Is this study still recruiting?

The registry lists this study as recruiting.

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