Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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731studies shown
Showing 126-150 of 731
RecruitingISRCTN55261332

Bipolarity: Lithium/ANti-Convulsant Evaluation

This study is looking at whether 1 can help people with bipolarity or Mental and Behavioural Disorders. Participants take part in 1 and complete follow-up assessments.

BipolarityOther
Countries
United Kingdom, France, Germany, Ireland, Italy, United States
Sponsor
University of Oxford (UK)
Condition
Bipolarity
Not Yet RecruitingNCT07556861

A Study Of Senyo Health With Comorbid Alcohol Use Disorder Treatment In Bipolar Patients

This study is testing a telehealth collaborative care platform for people living with bipolarity and alcohol use difficulties. Participants use the Senyo Health support approach and complete follow-up assessments to see whether it improves retention and substance use outcomes.

BipolarityOtherOver 18 Years
Countries
United States
Sponsor
Mayo Clinic
Condition
Bipolarity
CompletedNCT07549581

A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode

This study assessed the safety and pharmacology of SEP-380135 in adults living with schizophrenia or a major depressive episode linked to bipolarity or major depressive disorder. The registry now lists the study as completed.

DepressionOtherFrom 18 Years to 55 Years
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Condition
Depression
CompletedNCT06419582

BHV-7000 Acute Treatment of Bipolar Mania

This study tested BHV-7000 as an acute treatment for manic episodes in bipolarity. The public registry page now lists the trial as completed.

BipolarityOtherFrom 18 Years to 75 Years
Countries
United States
Sponsor
Biohaven Therapeutics Ltd.
Condition
Bipolarity
CompletedNCT06605599

Study of Oral ABBV-932 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Bipolar I or II Disorder

This completed Phase 2 study tested whether the oral investigational medication ABBV-932 was safe and could improve depressive episodes in adults living with bipolarity type I or II. Participants were assigned to one of three ABBV-932 dose groups or to placebo, took capsules once daily for 6 weeks, and then had a 4-week safety follow-up.

BipolarityOtherFrom 18 Years to 65 Years
Countries
Japan, United States
Sponsor
AbbVie
Condition
Bipolarity
CompletedNCT06273774

A Study of Elpipodect (MK-8189) in Participants With Bipolarity I (MK-8189-020)

This study exists to better understand the safety of the medication Elpipodect and how manageable it feels in practice. For people living with Bipolarity, that matters because care needs to work in daily life, not just in theory.

BipolarityOtherFrom 18 Years to 60 Years
Countries
United States
Sponsor
Merck Sharp & Dohme LLC
Condition
Bipolarity
RecruitingNCT07540338

A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolarity type I

This study exists to compare options and see whether blood tests and biological markers offers something meaningfully different. Researchers are trying to understand how people respond to blood tests and biological markers in practice and what may need to be adjusted.

BipolarityDrugFrom 18 Years to 65 Years
Countries
United States
Sponsor
Alzamend Neuro, Inc.
Condition
Bipolarity
Not Yet RecruitingNCT07528638

Intraoperative Neuromonitoring (IONM) and Bipolar Electrocautery (BE) During Axillary Lymph Node Dissection (ALND)

This study exists to see whether symptom tracking and monitoring can make care clearer and more responsive. Researchers are trying to understand whether symptom tracking and monitoring can give earlier or clearer feedback during care.

BipolarityProcedureFrom 18 Years to 70 Years
Countries
United States
Sponsor
University of Cincinnati
Condition
Bipolarity
CompletedNCT05317481

Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms

This study exists to understand how psychoeducation, a guided learning and support program, holds up over time after the earliest research stage. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can improve sleep, daily rhythms, and longer-term stability.

DepressionOtherFrom 16 Years to 29 Years
Countries
United States
Sponsor
Yale University
Condition
Depression
Active Not RecruitingNCT03349528

Probiotics to Prevent Relapse After Hospitalization for Depression in bipolarity

This study exists to compare options and see whether this type of care offers something meaningfully different. Researchers are trying to understand whether this type of care can better prevent setbacks and support longer-term stability.

BipolarityBiologicalFrom 18 Years to 65 Years
Countries
United States
Sponsor
Sheppard Pratt Health System
Condition
Bipolarity
CompletedNCT01470781

Treatment to Enhance Cognition in Bipolarity

This study exists to compare options and see whether brain scans or other body measurements offers something meaningfully different. Researchers are trying to understand whether brain scans or other body measurements can improve attention, thinking, or day-to-day functioning.

BipolarityOtherFrom 18 Years to 50 Years
Countries
United States
Sponsor
Mclean Hospital
Condition
Bipolarity
TerminatedNCT05724953

Alexithymia Intervention for Suicide

This study exists to see whether psychoeducation, a guided learning and support program, is workable and worth testing more broadly. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can make support easier to access outside standard clinic visits.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
WithdrawnNCT06384521

Lifestyle MIND- Feasibility of Wait-list Control

This study exists to compare options and see whether questionnaires and follow-up reports offers something meaningfully different. Researchers are trying to understand whether questionnaires and follow-up reports can better prevent setbacks and support longer-term stability.

SchizophreniaOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
The University of Texas Health Science Center at San Antonio
Condition
Schizophrenia
CompletedNCT04284267

Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders

This study exists to explore whether a digital app or remote support tool could improve care and understanding. Researchers are trying to understand what a digital app or remote support tool can reveal about signals in the brain or body that may guide care later on.

BipolarityOtherFrom 22 Years to 55 Years
Countries
United States
Sponsor
Massachusetts General Hospital
Condition
Bipolarity
CompletedNCT05380583

Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study

This study exists to see whether a digital app or remote support tool can play a useful role in care. Researchers are trying to understand whether a digital app or remote support tool can work better when mental health difficulties overlap with substance use.

SchizophreniaOtherFrom 18 Years to 70 Years
Countries
United States
Sponsor
Mclean Hospital
Condition
Schizophrenia
CompletedNCT05030272

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings

This study exists to see whether smoking support or smoking-related treatment is workable and worth testing more broadly. Researchers are trying to understand whether smoking support or smoking-related treatment can work better when mental health difficulties overlap with substance use.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
Wake Forest University Health Sciences
Condition
Depression
CompletedNCT05127837

CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies

This study exists to explore whether cognitive behavioural therapy, a structured talking treatment, could improve care and understanding. Researchers are trying to understand whether cognitive behavioural therapy, a structured talking treatment, can improve attention, thinking, or day-to-day functioning.

SchizophreniaOtherFrom 18 Years to 100 Years
Countries
United States
Sponsor
University of Washington
Condition
Schizophrenia
CompletedNCT03953417

Pilot Accelerated Theta Burst in Treatment-Resistant Depression in bipolarity

This study exists to see whether a therapy or guided support program can play a useful role in care. Researchers are trying to understand what a therapy or guided support program can reveal about signals in the brain or body that may guide care later on.

DepressionOtherFrom 18 Years to 80 Years
Countries
United States
Sponsor
Stanford University
Condition
Depression