Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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1371studies shown
Showing 1,226-1,250 of 1,371
CompletedNCT05685511

Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery

This study exists to understand what helps a medication treatment work in everyday practice, not just under ideal conditions. Researchers are trying to understand what helps a medication treatment stay useful, realistic, and easier to follow over time.

AnxietyOtherOver 60 Years
Countries
United States
Sponsor
Washington University School of Medicine
Condition
Anxiety
Not Yet RecruitingNCT07499583

Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder

This study exists to see whether a therapy or guided support program can make care clearer and more responsive. Researchers are trying to understand whether a therapy or guided support program can work better when mental health difficulties overlap with substance use.

DepressionOtherFrom 18 Years to 70 Years
Countries
United States
Sponsor
Indiana University
Condition
Depression
CompletedNCT06548022

Rare Group Problem Management Plus

This study exists to see whether psychoeducation, a guided learning and support program, can make care clearer and more responsive. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can make support easier to access outside standard clinic visits.

DepressionOtherFrom 18 Years to 99 Years
Countries
United States
Sponsor
Children's National Research Institute
Condition
Depression
CompletedNCT06138691

KET-RO Plus RO DBT for Treatment Resistant Depression

This study exists to see whether a therapy or guided support program is workable and worth testing more broadly. Researchers are trying to understand how people respond to a therapy or guided support program in practice and what may need to be adjusted.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
Washington University School of Medicine
Condition
Depression
CompletedNCT06280235

A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine

This study exists to compare options and see whether a therapy or guided support program offers something meaningfully different. Researchers are trying to understand what a therapy or guided support program could change in day-to-day care and decision-making.

DepressionOtherFrom 18 Years to 65 Years
Countries
Belgium, Bulgaria, China, Czech Republic, Germany, Japan, United States
Sponsor
Boehringer Ingelheim
Condition
Depression
CompletedNCT06216691

Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms

This study exists to understand how cognitive behavioural therapy, a structured talking treatment, holds up over time after the earliest research stage. Researchers are trying to understand whether cognitive behavioural therapy, a structured talking treatment, can make support easier to access outside standard clinic visits.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
Brigham and Women's Hospital
Condition
Depression
CompletedNCT06340958

A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder

This study exists to compare options and see whether the medication CLE-100 offers something meaningfully different. Researchers are trying to understand how people respond to the medication CLE-100 in practice and what may need to be adjusted.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
Clexio Biosciences Ltd.
Condition
Depression
CompletedNCT05966129

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial)

This study exists to see whether a therapy or guided support program can make care clearer and more responsive. Researchers are trying to understand whether a therapy or guided support program can work better when mental health difficulties overlap with substance use.

DepressionOtherOver 8 Years
Countries
United States
Sponsor
Duke University
Condition
Depression
CompletedNCT06053307

Treating Psychosocial Distress in Glaucoma

This study exists to see whether acceptance and commitment therapy, a talking treatment, is workable and worth testing more broadly. Researchers are trying to understand how people respond to acceptance and commitment therapy, a talking treatment, in practice and what may need to be adjusted.

AnxietyOtherOver 18 Years
Countries
United States
Sponsor
Duke University
Condition
Anxiety
CompletedNCT05144789

Personalized Therapeutic Neuromodulation for Anhedonic Depression

This study exists to explore whether a therapy or guided support program could improve care and understanding. Researchers are trying to understand what a therapy or guided support program can reveal about signals in the brain or body that may guide care later on.

DepressionOtherFrom 18 Years to 80 Years
Countries
United States
Sponsor
Stanford University
Condition
Depression
CompletedNCT05487885

Anhedonia, Development, and Emotions: Phenotyping and Therapeutics

This study exists to see whether a digital app or remote support tool can make care clearer and more responsive. Researchers are trying to understand whether a digital app or remote support tool can better support energy, concentration, and everyday functioning.

DepressionOtherFrom 15 Years to 25 Years
Countries
United States
Sponsor
Erika Forbes
Condition
Depression
CompletedNCT05402657

The RAFT ECT Study

This study exists to understand how a therapy or guided support program holds up over time after the earliest research stage. Researchers are trying to understand whether a therapy or guided support program can improve attention, thinking, or day-to-day functioning.

DepressionOtherOver 18 Years
Countries
Australia, United States
Sponsor
The George Institute
Condition
Depression
CompletedNCT06001346

CBT+ for Depression

This study exists to see whether cognitive behavioural therapy, a structured talking treatment, can play a useful role in care. Researchers are trying to understand whether cognitive behavioural therapy, a structured talking treatment, can improve attention, thinking, or day-to-day functioning.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
University of Wisconsin, Madison
Condition
Depression
CompletedNCT01743716

Genetic and Neural Predictors of Adolescent Depression

This study exists to see whether questionnaires and follow-up reports can make care clearer and more responsive. Researchers are trying to understand whether questionnaires and follow-up reports can give earlier or clearer feedback during care.

DepressionOtherOver 12 Years
Countries
United States
Sponsor
Mclean Hospital
Condition
Depression
TerminatedNCT06635135

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

This study exists to understand what helps the medication Aticaprant work in everyday practice, not just under ideal conditions. Researchers are trying to understand what the medication Aticaprant could change in day-to-day care and decision-making.

DepressionOtherFrom 18 Years to 64 Years
Countries
Argentina, Belgium, Brazil, Bulgaria, France, Germany, Greece, Mexico, Poland, Romania, Spain, Turkey, United States
Sponsor
Janssen Research & Development, LLC
Condition
Depression
WithdrawnNCT05710887

N2O for Acute Suicidality and Depression in the ED

This study exists to see whether a therapy or guided support program is workable and worth testing more broadly. Researchers are trying to understand whether a therapy or guided support program can improve attention, thinking, or day-to-day functioning.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
University of Chicago
Condition
Depression
CompletedNCT03428828

Neurofeedback for Treatment Resistant Depression

This study exists to explore whether brain scans or other body measurements could improve care and understanding. Researchers are trying to understand whether brain scans or other body measurements can improve attention, thinking, or day-to-day functioning.

DepressionOtherFrom 18 Years to 55 Years
Countries
United States
Sponsor
Kymberly Young
Condition
Depression
CompletedNCT05224063

Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression

This study exists to see whether a digital app or remote support tool can play a useful role in care. Researchers are trying to understand whether a digital app or remote support tool can better support energy, concentration, and everyday functioning.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
Stanford University
Condition
Depression
CompletedNCT04208217

Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?

This study exists to see whether a therapy or guided support program can play a useful role in care. Researchers are trying to understand whether a therapy or guided support program can work better when mental health difficulties overlap with substance use.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
CompletedNCT06183580

Teen Brain Training (TBT)

This study exists to compare options and see whether a digital app or remote support tool offers something meaningfully different. Researchers are trying to understand what a digital app or remote support tool can reveal about signals in the brain or body that may guide care later on.

DepressionOtherFrom 11 Years to 18 Years
Countries
United States
Sponsor
University of Minnesota
Condition
Depression