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TerminatedNCT06635135

Aticaprant Plus an Antidepressant for depression

This study was terminated in the United States, in France, in Belgium, .... It is testing aticaprant Plus an Antidepressant for depression.

Depression, AnhedoniaDrugFrom 18 Years to 64 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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In plain English

Key information made simple

What is this study testing?

This study is testing whether Aticaprant Plus an Antidepressant may be useful for adults experiencing depression.

What would participation involve?

Participants may receive Aticaprant Plus an Antidepressant, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Argentina, in Belgium, and in Brazil.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)

  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: September 19, 2024
Recruitment status
Terminated
Enrollment listed in the registry
47
Sponsor
Janssen Research & Development, LLC
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug, OTHER
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, France, Belgium, ...
Age range
From 18 Years to 64 Years
Official registry ID
NCT06635135
Official title
A Randomized, Double-blind, Multicenter, Placebo-controlled Study of Adjunctive Aticaprant Plus an Antidepressant for Relapse Prevention in Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Argentina · 2 sites
  • Hospital Italiano de Buenos Aires
    Buenos Aires
    Site status: Not listed — confirm with the team
  • Centro Medico Instituto Modelo de Neurologia y Neurorehabilitacion
    Córdoba
    Site status: Not listed — confirm with the team
Belgium · 5 sites
  • Anima
    Alken
    Site status: Not listed — confirm with the team
  • AZ Sint-Lucas
    Assebroek
    Site status: Not listed — confirm with the team
  • UZ Brussel
    Brussels
    Site status: Not listed — confirm with the team
  • AZ Oudenaarde
    Oudenaarde
    Site status: Not listed — confirm with the team
  • Vitaz
    Sint-Niklaas
    Site status: Not listed — confirm with the team
Brazil · 2 sites
  • CAEP Centro Avancado De Estudos E Pesquisas
    Campinas
    Site status: Not listed — confirm with the team
  • Centro Integrado Facili
    São Bernardo do Campo
    Site status: Not listed — confirm with the team
Bulgaria · 5 sites
  • Mental Health Center - Rousse
    Rousse
    Site status: Not listed — confirm with the team
  • Medical Centre Akademika EOOD
    Sofia
    Site status: Not listed — confirm with the team
  • DCC 'Sv. Vrach and Sv. Sv. Kuzma and Damyan', OOD
    Sofia
    Site status: Not listed — confirm with the team
  • Diagnostic Consulting Center Mladost - M Varna
    Varna
    Site status: Not listed — confirm with the team
  • Mental Health Center - Vratsa EOOD
    Vratsa
    Site status: Not listed — confirm with the team
France · 5 sites
  • CHRU Besancon Hopital Jean Minjoz
    Besançon
    Site status: Not listed — confirm with the team
  • Hopital la Colombiere
    Montpellier
    Site status: Not listed — confirm with the team
  • CHU de Nantes hotel Dieu
    Nantes
    Site status: Not listed — confirm with the team
  • CHS du Rouvray
    Sotteville-lès-Rouen
    Site status: Not listed — confirm with the team
  • Hopital Sainte Musse
    Toulon
    Site status: Not listed — confirm with the team
Germany · 9 sites
  • Klinische Forschung Berlin-Mitte GmbH
    Berlin
    Site status: Not listed — confirm with the team
  • Praxis Dr. med. Kirsten Hahn
    Berlin
    Site status: Not listed — confirm with the team
  • Pharmakologisches Studienzentrum Chemnitz GmbH
    Chemnitz
    Site status: Not listed — confirm with the team
  • Universitatsklinikum Frankfurt
    Frankfurt am Main
    Site status: Not listed — confirm with the team
  • Klinische Forschung Hamburg
    Hamburg
    Site status: Not listed — confirm with the team
  • Oberhavel Kliniken GmbH
    Hennigsdorf
    Site status: Not listed — confirm with the team
  • Universitaetsklinikum Muenster
    Münster
    Site status: Not listed — confirm with the team
  • Boehm Peters Praxis fur Psychiatrie Psychotherapie Neurologie PartGmbB
    Rosenheim
    Site status: Not listed — confirm with the team
  • Klinische Forschung Schwerin GmbH
    Schwerin
    Site status: Not listed — confirm with the team
Greece · 5 sites
  • Eginitio Hospital
    Athens
    Site status: Not listed — confirm with the team
  • Attikon University General Hospital of Attica
    Athens
    Site status: Not listed — confirm with the team
  • University Hospital of Heraklion
    Heraklion
    Site status: Not listed — confirm with the team
  • University General Hospital of Ioannina
    Ioannina
    Site status: Not listed — confirm with the team
  • G Papanikolaou Hospital of Thessaloniki
    Thessaloniki
    Site status: Not listed — confirm with the team
Mexico · 4 sites
  • Hospital Aranda de la Parra S A de C V
    León
    Site status: Not listed — confirm with the team
  • Ketamine Mexico S de RL de C V
    Mexico City
    Site status: Not listed — confirm with the team
  • Human Science Research Trials S de RL de CV
    México
    Site status: Not listed — confirm with the team
  • cit NEUROPSIQUE
    Monterrey
    Site status: Not listed — confirm with the team
Poland · 10 sites
  • Osrodek Badan Klinicznych CLINSANTE S C Ewa Galczak Nowak Malgorzata Trzaska
    Bydgoszcz
    Site status: Not listed — confirm with the team
  • NZOZ Euromedica Grudziadz
    Grudziądz
    Site status: Not listed — confirm with the team
  • Niepubliczny Zaklad Opieki Psychiatrycznej MENTIS
    Leszno
    Site status: Not listed — confirm with the team
  • Centrum Medyczne Luxmed Sp z o o
    Lublin
    Site status: Not listed — confirm with the team
  • Praktyka Lekarska dr n med Malgorzata Wojtanowska Bogacka
    Poznan
    Site status: Not listed — confirm with the team
  • Indywidualna Specjalistyczna Praktyka Lekarska Agnieszka Remlinger Molenda
    Suchy Las
    Site status: Not listed — confirm with the team
  • Care Access Warszawa
    Warsaw
    Site status: Not listed — confirm with the team
  • Szpital Nowowiejski Osrodek Badan Klinicznych
    Warsaw
    Site status: Not listed — confirm with the team
  • MTZ Clinical Research Powered by Pratia
    Warsaw
    Site status: Not listed — confirm with the team
  • Centrum Zdrowia Mosty
    Wroclaw
    Site status: Not listed — confirm with the team
Romania · 7 sites
  • Spitalul Clinic de Psihiatrie Prof Dr Alexandru Obregia
    Bucharest
    Site status: Not listed — confirm with the team
  • Centrul de Evaluarea si Tratament al Toxicodependentelor pentru Tineri Sf. Stelian
    Bucharest
    Site status: Not listed — confirm with the team
  • Centrul Medical Melchisedec
    Craiova
    Site status: Not listed — confirm with the team
  • Spitalul Clinic de Neuropsihiatrie
    Craiova
    Site status: Not listed — confirm with the team
  • CMI Dr. Sarpe Marcel-Claudiu
    Focşani
    Site status: Not listed — confirm with the team
  • Spitalul De Psihiatrie Elisabeta Doamna Galaţi
    Galați
    Site status: Not listed — confirm with the team
  • Spitalul Clinic De Psihiatrie Doctor Gheorghe Preda
    Sibiu
    Site status: Not listed — confirm with the team
Spain · 9 sites
  • Hosp. Univ. de Basurto
    Bilbao
    Site status: Not listed — confirm with the team
  • Hosp Reina Sofia
    Córdoba
    Site status: Not listed — confirm with the team
  • Hosp. Univ. Virgen de Las Nieves
    Granada
    Site status: Not listed — confirm with the team
  • Hosp. Univ. La Paz
    Madrid
    Site status: Not listed — confirm with the team
  • Hosp Virgen de La Victoria
    Málaga
    Site status: Not listed — confirm with the team
  • Hosp. Univ. Son Espases
    Palma
    Site status: Not listed — confirm with the team
  • Clinica Univ. de Navarra
    Pamplona
    Site status: Not listed — confirm with the team
  • Hosp. El Bierzo
    Ponferrada
    Site status: Not listed — confirm with the team
  • Hosp. Royo Villanova
    Zaragoza
    Site status: Not listed — confirm with the team
Türkiye · 1 site
  • Erenkoy Mental Health Hospital
    Istanbul
    Site status: Not listed — confirm with the team
United States · 31 sites
  • Preferred Research Partners
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Wake Research PRI Encino
    Encino, California
    Site status: Not listed — confirm with the team
  • Wr Pri Llc
    Newport Beach, California
    Site status: Not listed — confirm with the team
  • ATP Clinical Research
    Orange, California
    Site status: Not listed — confirm with the team
  • Myndful Research
    Redlands, California
    Site status: Not listed — confirm with the team
  • Artemis Institute for Clinical Research
    San Diego, California
    Site status: Not listed — confirm with the team
  • UHC Research
    Doral, Florida
    Site status: Not listed — confirm with the team
  • Pharmax Research Clinic Inc
    Miami, Florida
    Site status: Not listed — confirm with the team
  • GTL Medical and Research Group
    Miami, Florida
    Site status: Not listed — confirm with the team
  • International Research Associates, LLC
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Harmony Clinical Research Inc
    North Miami Beach, Florida
    Site status: Not listed — confirm with the team
  • APG Research LLC
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • Interventional Psychiatry of Tampa Bay
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Synexus Clinical Research US Inc
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Chicago Research Center
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Psychiatric Medicine Associates LLC
    Skokie, Illinois
    Site status: Not listed — confirm with the team
  • Continental Clinical Solutions
    Towson, Maryland
    Site status: Not listed — confirm with the team
  • Massachusetts General Hospital
    Boston, Massachusetts
    Site status: Not listed — confirm with the team
  • University of Missouri Health Care
    Columbia, Missouri
    Site status: Not listed — confirm with the team
  • IMA Clinical Research PC
    Albuquerque, New Mexico
    Site status: Not listed — confirm with the team
  • Integrative Clinical Trials LLC
    Brooklyn, New York
    Site status: Not listed — confirm with the team
  • Bioscience Research LLC
    Mount Kisco, New York
    Site status: Not listed — confirm with the team
  • Patient Priority Clinical Sites LLC
    Cincinnati, Ohio
    Site status: Not listed — confirm with the team
  • Insight Clinical Trials
    Independence, Ohio
    Site status: Not listed — confirm with the team
  • Laureate Institute for Brain Research
    Tulsa, Oklahoma
    Site status: Not listed — confirm with the team
  • Keystone Clinical Studies LLC
    Plymouth Meeting, Pennsylvania
    Site status: Not listed — confirm with the team
  • Coastal Carolina Research Center
    North Charleston, South Carolina
    Site status: Not listed — confirm with the team
  • InSite Clinical Research LLC
    DeSoto, Texas
    Site status: Not listed — confirm with the team
  • Earle Research
    Friendswood, Texas
    Site status: Not listed — confirm with the team
  • Alpine Research Organization
    Clinton, Utah
    Site status: Not listed — confirm with the team
  • Elligo Integrated Research Sites Integrated Clinical Research LLC Integrated Psych
    St. George, Utah
    Site status: Not listed — confirm with the team

Ask HopeStage to help me review this study

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Study ID: NCT06635135. We help you review the study, but cannot decide medical eligibility.
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Aticaprant, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 64 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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