RecruitingEUCTR 2021-000350-26

A double blind, randomized, placebo-controlled, adaptive 24-week Phase IIb trial to evaluate the efficacy of vafidemstat in negative symptoms and cognitive impairment associated with schizophrenia....

This EU register entry describes an interventional medicine trial, designed to assign participants a study treatment. The protocol sets out the treatment, eligibility criteria and assessments. Check the source details below for country statuses and any transfer to CTIS.

SchizophreniaDrug

In plain English

Key information made simple

What the source confirms

What should you check before joining?

Check the official protocol for eligibility, treatment, visits and assessments. If recruitment is listed, confirm with the team that a specific centre is still accepting participants before taking any next step.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View the historical EU CTR record

Recruitment and eligibility
Is a site open, and who can take part?
Visits and time
Where are visits, can any be remote, and how much time is needed?
Costs and support
What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?

Study clarity

Things to check before joining

Study start dateNot clearly listed

Recruitment status: Recruiting
Enrollment listed in the registry: Not clearly listed
Sponsor: Oryzon Genomics, S.A.
Sponsor type: Unknown or unclear
Study type: Drug
Intervention type: Medication / drug
Study phase: Phase 2
Locations: Bulgaria, Poland, Romania, ...
Age range: Not clearly listed
Official registry ID: EUCTR 2021-000350-26
Official title: A double blind, randomized, placebo-controlled, adaptive 24-week Phase IIb trial to evaluate the efficacy of vafidemstat in negative symptoms and cognitive impairment associated with schizophrenia....

Check recruitment and locations

EU CTR and CTIS records checked by HopeStage on 15 September 2026. Registry information can change. Always confirm availability with the research team.

This study transferred to CTIS. HopeStage uses that newer record for the displayed status. A country's status does not guarantee that an individual site accepts participants.

View the historical EU CTR record View the current CTIS record

Current CTIS country statuses

Bulgaria : Ongoing, recruiting
Poland : Authorised, recruitment pending
Romania : Authorised, recruiting
Slovakia : Authorised, recruiting
Spain : Ongoing, recruiting

Historical EU CTR country statuses

Spain : Ongoing

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Bulgaria · 11 sites

Multiprofile Hospital For Active Treatment Dr. Hristo Stambolski EOOD — Department of Psychiatry
Kazanlik
Site status: Not listed — confirm with the team
State Psychiatric Hospital Lovech — First Men's Ward Women's Ward
Lovech
Site status: Not listed — confirm with the team
State Psychiatric Saint Ivan Rilski Hospital — Department of general psychiatry of closed-type for adult men and for adult woman
Novi Iskir
Site status: Not listed — confirm with the team
Higya–DCC OOD — Psychiatry
Pazardzhik
Site status: Not listed — confirm with the team
University Multiprofile Hospital For Active Treatment Dr. Georgi Stranski EAD — First Psychiatric Clinic
Pleven
Site status: Not listed — confirm with the team
Outpatient Clinic for Indiv. Practice for Spec.Med. Care in Psychiatry-Dr.Madlena Dimitrova Borisova — Psychiatry
Razgrad
Site status: Not listed — confirm with the team
Center For Mental Health Ruse EOOD — Women's and Men's department for persons with severe mental disorders.Department "inpatient daycare"
Ruse
Site status: Not listed — confirm with the team
MBAL Dr. Ivan Seliminski Sliven AD — Department of Psychiatry
Sliven
Site status: Not listed — confirm with the team
Medical Center Intermedica Ltd. — Psychiatry
Sofia
Site status: Not listed — confirm with the team
Medical Center Hera EOOD — Psychiatry
Sofiya
Site status: Not listed — confirm with the team
Diagnostics-Consultancy Center Mladost M Varna OOD — Psychiatric office
Varna
Site status: Not listed — confirm with the team

Poland · 5 sites

Centrum Badan Klinicznych Pi-House Sp. z o.o. — Psychiatria
Gdansk
Country status: Not Yet Recruiting
Instytut Naukowo-Badawczy Sp. z o.o. — Psychiatria
Lublin
Country status: Not Yet Recruiting
Nowy Szpital w Olkuszu — Psychiatria
Olkusz
Country status: Not Yet Recruiting
Centrum Medyczne Hcp Sp. z o.o. — Psychiatria
Poznan
Country status: Not Yet Recruiting
Clinhouse Sp. z o.o. — Psychiatria
Zabrze
Country status: Not Yet Recruiting

Romania · 6 sites

Spitalul Clinic De Psihiatrie Prof.Dr.Alexandru Obregia — Psihiatrie
Bucharest
Site status: Not listed — confirm with the team
Spitalul Clinic De Psihiatrie Prof.Dr.Alexandru Obregia — Psihiatrie
Bucharest
Site status: Not listed — confirm with the team
Spitalul Clinic Judetean De Urgenta Cluj — Psihiatrie
Cluj-Napoca
Site status: Not listed — confirm with the team
Medicover S.R.L. — Psihiatrie
Jassi
Site status: Not listed — confirm with the team
Psihoconcept Med S.R.L. — Psihiatrie
Selimbar
Site status: Not listed — confirm with the team
Spitalul Clinic De Psihiatrie Dr. Gheorghe Preda Sibiu — Psihiatrie
Sibiu
Site status: Not listed — confirm with the team

Slovakia · 3 sites

Epamed s.r.o. — Psychiatry
Kosice - Zapad
Site status: Not listed — confirm with the team
Mentum s.r.o. — Psychiatry
Stare Mesto
Site status: Not listed — confirm with the team
Crystal Comfort s.r.o. — Psychiatry
Vranov Nad Toplou
Site status: Not listed — confirm with the team

Spain · 16 sites

Hospital Universitario Fundacion Alcorcon — Psiquiatría
Alcorcon
Site status: Not listed — confirm with the team
Hospital Clinic De Barcelona — Psiquiatría
Barcelona
Site status: Not listed — confirm with the team
Hospital De La Santa Creu I Sant Pau — Psiquiatría
Barcelona
Site status: Not listed — confirm with the team
Hospital Del Mar — Psiquiatría
Barcelona
Site status: Not listed — confirm with the team
Hospital Universitari Vall D Hebron — Psiquiatría
Barcelona
Site status: Not listed — confirm with the team
Hospital Universitario De Burgos — Psiquiatría
Burgos
Site status: Not listed — confirm with the team
Hospital General Universitario De Elche — Psiquiatría
Elche
Site status: Not listed — confirm with the team
Hospital Clinico San Carlos — Psiquiatría
Madrid
Site status: Not listed — confirm with the team
Hospital Universitario General De Villalba — Psiquiatría
Madrid
Site status: Not listed — confirm with the team
Hospital Quironsalud Malaga — Psiquiatría
Malaga
Site status: Not listed — confirm with the team
CENTRO DE SALUD MENTAL I - LA ERIA - OVIEDO — Psiquiatría
Oviedo
Site status: Not listed — confirm with the team
Clinica Universidad De Navarra — Psiquiatría
Pamplona
Site status: Not listed — confirm with the team
University Hospital Virgen Del Rocio S.L. — Psiquiatría
Sevilla
Site status: Not listed — confirm with the team
Hospital Universitario De Torrejon — Psiquiatría
Torrejon De Ardoz
Site status: Not listed — confirm with the team
Complexo Hospitalario Universitario De Vigo — Psiquiatría
Vigo
Site status: Not listed — confirm with the team
Complejo Asistencial De Zamora Hospital Provincial De Zamora — Psiquiatría
Zamora
Site status: Not listed — confirm with the team

Want help reviewing this study?

Study ID: EUCTR 2021-000350-26. We help you review the study, but cannot decide medical eligibility.

In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What does the official source confirm?

Is this study recruiting?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

How can I check the participation requirements?

Check the official protocol for the criteria, treatment and planned assessments. The research team must confirm visits, risks, open centres and your eligibility.

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