This study is completed in the United States, in Bulgaria, in Estonia, .... It is testing intranasal Esketamine for depression.
Depression, SuicidalityDrugFrom 18 Years to 64 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Then choose your country and confirm availability with each study site.
In plain English
Key information made simple
What is this study testing?
This study is testing whether Intranasal Esketamine may be useful for adults experiencing depression.
What would participation involve?
Participants may receive Intranasal Esketamine, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Bulgaria, in Estonia, and in Germany.
Who is it mainly for?
This study appears to be mainly for adults with depression.
What should you check before joining?
Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.
Your next step
Check the study details
Check the official source, then confirm these points with the research team.
Where are visits, can any be remote, and how much time is needed?
Costs and support
What costs, reimbursement or compensation apply?
Before joining
Questions to ask before joining
What are the exact eligibility criteria, and what could exclude someone?
How many visits, assessments, or follow-ups are expected, and over what period?
What risks, side effects, practical burdens, or alternatives should be understood first?
Who should be contacted to confirm locations, timing, compensation, and next steps?
Study clarity
Things to check before joining
Study start dateStarted: June 9, 2017
Recruitment status
Completed
Enrollment listed in the registry
226
Sponsor
Janssen Research & Development, LLC
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug, OTHER
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, Bulgaria, Estonia, ...
Age range
From 18 Years to 64 Years
Official registry ID
NCT03039192
Official title
A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Subjects Assessed to be at Imminent Risk for Suicide
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Bulgaria · 5 sites
Regional Psychiatric Dispansery
Bulgaria
Site status: Not listed — confirm with the team
Mental Health Center Prof. Dr. Ivan Temkov
Burgas
Site status: Not listed — confirm with the team
State Psychiatric Hospital - Lovech
Lovech
Site status: Not listed — confirm with the team
UMHAT 'Sveti Georgi'-Plovdiv
Plovdiv
Site status: Not listed — confirm with the team
Military Medical Academy Multiprofile Hospital for Active Treatment Sofia
Sofia
Site status: Not listed — confirm with the team
Estonia · 2 sites
North Estonian Medical Centre Foundation
Tallinn
Site status: Not listed — confirm with the team
Tartu University Hospital
Tartu
Site status: Not listed — confirm with the team
Germany · 3 sites
Vivantes Humboldt Klinikum
Berlin
Site status: Not listed — confirm with the team
Universitatsklinikum Frankfurt
Frankfurt am Main
Site status: Not listed — confirm with the team
Klinik für Psychiatrie und Psychotherapie
Freiburg im Breisgau
Site status: Not listed — confirm with the team
Hungary · 5 sites
Eszak Kozep budai Centrum Uj Szent Janos Korhaz es Szakrendelo Budai Csaladkozpontu
Budapest
Site status: Not listed — confirm with the team
Semmelweis Egyetem Kútvölgyi Klinikai Tömb
Budapest
Site status: Not listed — confirm with the team
Nyiro Gyula Korhaz
Budapest
Site status: Not listed — confirm with the team
Petz Aladar Megyei Oktato Korhaz
Győr
Site status: Not listed — confirm with the team
Pecsi Tudomanyegyetem Klinikai Kozpont
Pécs
Site status: Not listed — confirm with the team
Malaysia · 4 sites
University Kebangsaan Malaysia Medical Centre
Cheras
Site status: Not listed — confirm with the team
Hospital Kuala Lumpur
Kuala Lumpur
Site status: Not listed — confirm with the team
University Malaya Medical Centre
Kuala Lumpur
Site status: Not listed — confirm with the team
Hospital Tuanku Jaafar
Seremban
Site status: Not listed — confirm with the team
Slovakia · 1 site
Fakultna nemocnica s poliklinikou v Ziline
Žilina
Site status: Not listed — confirm with the team
South Africa · 2 sites
Flexivest 14 Research
Cape Town
Site status: Not listed — confirm with the team
Juan Schrönen - Western Cape South Africa
Welgemoed
Site status: Not listed — confirm with the team
South Korea · 5 sites
Chonnam National University Hospital
Gwangju
Site status: Not listed — confirm with the team
Korea University Ansan Hospital
Gyeonggi-do
Site status: Not listed — confirm with the team
Kyung Hee University Medical Center
Seoul
Site status: Not listed — confirm with the team
Samsung Medical Center
Seoul
Site status: Not listed — confirm with the team
Seoul National University Hospital
Seoul
Site status: Not listed — confirm with the team
Spain · 8 sites
Hosp. Univ. Fundacion Alcorcon
Alcorcón
Site status: Not listed — confirm with the team
Hosp Univ Vall D Hebron
Barcelona
Site status: Not listed — confirm with the team
Hosp Clinic de Barcelona
Barcelona
Site status: Not listed — confirm with the team
Inst. Internac. Neurociencias Aplicadas
Barcelona
Site status: Not listed — confirm with the team
Hosp. Univ. de Basurto
Bilbao
Site status: Not listed — confirm with the team
Hosp. Univ. Ramon Y Cajal
Madrid
Site status: Not listed — confirm with the team
Clinica Univ. de Navarra
Pamplona
Site status: Not listed — confirm with the team
Benito Menni Comp. Asist. Salut Mental
Sant Boi de Llobregat
Site status: Not listed — confirm with the team
Taiwan · 4 sites
Tri-Service Genaral Hospital
Neihu District
Site status: Not listed — confirm with the team
Taipei Medical University Shuang Ho Hospital
New Taipei City
Site status: Not listed — confirm with the team
Chung Shan Medical University Hospital
Taichung
Site status: Not listed — confirm with the team
Taipei Veterans General Hospital
Taipei
Site status: Not listed — confirm with the team
United States · 17 sites
UAB Department of Psychiatry and Behavioral Neurobiology
Birmingham, Alabama
Site status: Not listed — confirm with the team
Metropolitan Neuro Behavioral Institute
Chandler, Arizona
Site status: Not listed — confirm with the team
Collaborative NeuroScience Network
Garden Grove, California
Site status: Not listed — confirm with the team
Yale University
New Haven, Connecticut
Site status: Not listed — confirm with the team
Rush University
Chicago, Illinois
Site status: Not listed — confirm with the team
Alexian Behavioral Health Hospital
Hoffman Estates, Illinois
Site status: Not listed — confirm with the team
University of Louisville Department of Psychiatry
Louisville, Kentucky
Site status: Not listed — confirm with the team
LSU Health Sciences Center New Orleans
New Orleans, Louisiana
Site status: Not listed — confirm with the team
Louisiana Clinical Research
Shreveport, Louisiana
Site status: Not listed — confirm with the team
Sheppard Pratt Health System
Baltimore, Maryland
Site status: Not listed — confirm with the team
CBH Health
Gaithersburg, Maryland
Site status: Not listed — confirm with the team
State University of New York
Buffalo, New York
Site status: Not listed — confirm with the team
Columbia University Medical Center
New York, New York
Site status: Not listed — confirm with the team
Clinical Trials of America
Hickory, North Carolina
Site status: Not listed — confirm with the team
The Ohio State University
Columbus, Ohio
Site status: Not listed — confirm with the team
Medical University of South Carolina
Charleston, South Carolina
Site status: Not listed — confirm with the team
University of Texas Southwestern Medical Center
Dallas, Texas
Site status: Not listed — confirm with the team
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT03039192. We help you review the study, but cannot decide medical eligibility.
In practice
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Important
Not medical advice
Information from public sources.
Are you the study sponsor? Contact us to update this page: hi@hopestage.com
FAQ
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving Esketamine, Placebo, Standard of Care. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 64 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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