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CompletedNCT03321526

Safety study of JNJ-42847922 in depression

This study is completed in the United States. It is testing JNJ-42847922 for depression.

DepressionDrugFrom 18 Years to 70 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

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Study start dateStarted: December 12, 2017
Recruitment status
Completed
Enrollment listed in the registry
107
Sponsor
Janssen Research & Development, LLC
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States
Age range
From 18 Years to 70 Years
Official registry ID
NCT03321526
Official title
A 6-Month, Multicenter, Double-Blind, Randomized, Flexible-Dose, Parallel-Group Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Subjects With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 50 sites
  • NoesisPharma Research
    Phoenix, Arizona
    Site status: Not listed — confirm with the team
  • Clinical Research Consortium Arizona
    Tempe, Arizona
    Site status: Not listed — confirm with the team
  • Woodland Research Northwest
    Rogers, Arkansas
    Site status: Not listed — confirm with the team
  • Collaborative NeuroScience Network
    Garden Grove, California
    Site status: Not listed — confirm with the team
  • Pacific Institute of Medical Sciences
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • National Research Institute
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • Excell Research Inc
    Oceanside, California
    Site status: Not listed — confirm with the team
  • Desert Valley Research
    Rancho Mirage, California
    Site status: Not listed — confirm with the team
  • Anderson Clinical Research
    Redlands, California
    Site status: Not listed — confirm with the team
  • Artemis Institute for Clinical Research
    San Diego, California
    Site status: Not listed — confirm with the team
  • Syrentis Clinical Research
    Santa Ana, California
    Site status: Not listed — confirm with the team
  • Research Center for Clinical Studies, Inc.
    Norwalk, Connecticut
    Site status: Not listed — confirm with the team
  • Clinical Research of South Florida
    Coral Gables, Florida
    Site status: Not listed — confirm with the team
  • SIH Research
    Kissimmee, Florida
    Site status: Not listed — confirm with the team
  • Premier Clinical Research
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Innova Clinical Trials
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Arocha Research Center Inc
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Suncoast Clinical Research
    New Port Richey, Florida
    Site status: Not listed — confirm with the team
  • Stedman Clinical Trials
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Northwest Behavioral Research Center
    Marietta, Georgia
    Site status: Not listed — confirm with the team
  • Suburban Clinical Research Group, Inc
    Bolingbrook, Illinois
    Site status: Not listed — confirm with the team
  • RxClinicals
    Crystal Lake, Illinois
    Site status: Not listed — confirm with the team
  • Alexian Brothers Health System
    Hoffman Estates, Illinois
    Site status: Not listed — confirm with the team
  • Psychiatric Medicine Associates LLC
    Skokie, Illinois
    Site status: Not listed — confirm with the team
  • American Research, LLC
    Jeffersonville, Indiana
    Site status: Not listed — confirm with the team
  • University of Iowa
    Iowa City, Iowa
    Site status: Not listed — confirm with the team
  • Phoenix Medical Research, Inc.
    Prairie Village, Kansas
    Site status: Not listed — confirm with the team
  • Johns Hopkins University School of Medicine
    Baltimore, Maryland
    Site status: Not listed — confirm with the team
  • BTC of New Bedford
    New Bedford, Massachusetts
    Site status: Not listed — confirm with the team
  • Boston Clinical Trials & Medical Research
    Roslindale, Massachusetts
    Site status: Not listed — confirm with the team
  • Rochester Center for Behavioral Medicine (RCBM)
    Rochester Hills, Michigan
    Site status: Not listed — confirm with the team
  • Midwest Research Group
    Saint Charles, Missouri
    Site status: Not listed — confirm with the team
  • PsychCare Consultants Research
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Clinical Research Consortium
    Las Vegas, Nevada
    Site status: Not listed — confirm with the team
  • SPRI Clinical Trials, LLC
    Brooklyn, New York
    Site status: Not listed — confirm with the team
  • CNS Research Science, Inc.
    Jamaica, New York
    Site status: Not listed — confirm with the team
  • Hapworth Psychiatric Medical PLLC
    New York, New York
    Site status: Not listed — confirm with the team
  • Carolina Partners c/o Tripha Life Sciences
    Raleigh, North Carolina
    Site status: Not listed — confirm with the team
  • Patient Priority Clinical Sites LLC
    Cincinnati, Ohio
    Site status: Not listed — confirm with the team
  • Intend Research
    Norman, Oklahoma
    Site status: Not listed — confirm with the team
  • IPS Research Company
    Oklahoma City, Oklahoma
    Site status: Not listed — confirm with the team
  • Sooner Clinical Research
    Oklahoma City, Oklahoma
    Site status: Not listed — confirm with the team
  • BTC Network
    Lincoln, Rhode Island
    Site status: Not listed — confirm with the team
  • Hawkins Psychiatry, PC
    Arlington, Texas
    Site status: Not listed — confirm with the team
  • Baylor College of Medicine
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Houston Endoscopy and Research Center, Inc.
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Texas Center for Drug Development Inc
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Pillar Clinical Research, LLC
    Richardson, Texas
    Site status: Not listed — confirm with the team
  • Ericksen Research and Development
    Clinton, Utah
    Site status: Not listed — confirm with the team
  • Northwest Clinical Research Center
    Bellevue, Washington
    Site status: Not listed — confirm with the team

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Study ID: NCT03321526. We help you review the study, but cannot decide medical eligibility.
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving JNJ-42847922, Placebo Matching to JNJ-42847922, Quetiapine XR, Placebo Matching to Quetiapine XR, Selective Serotonin Reuptake Inhibitor (SSRI), Serotonin-Norepinephrine Reuptake Inhibitor (SNRI). Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 70 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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