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Study ID: NCT04512066. We help you review the study, but cannot decide medical eligibility.
CompletedNCT04512066
Safety study of RO6889450 in schizophrenia
This study is completed in the United States, in Japan, in Russia, .... It is testing RO6889450 for schizophrenia.
SchizophreniaDrugFrom 18 Years to 45 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Japan · 2 sites
- National Center of Neurology and PsychiatryTokyoSite status: Not listed — confirm with the team
- Seishinkai Okehazama Hospital Fujita Kokoro Care CenterToyoakeSite status: Not listed — confirm with the team
Russia · 8 sites
- Psychiatry Hospital #1 n.a. P.P.KashchenkoSaint Petersburg, Sankt-PeterburgSite status: Not listed — confirm with the team
- Leningradskiy Regional Psychoneurologic DispensarySaint Petersburg, Sankt-PeterburgSite status: Not listed — confirm with the team
- Psychiatric Hospital St Nicholas the WonderworkerSaint Petersburg, Sankt-PeterburgSite status: Not listed — confirm with the team
- City Psychiatry Hospital #3 n.a. I.I. Skvortsov-StepanovSaint Petersburg, Sankt-PeterburgSite status: Not listed — confirm with the team
- FSBI National Medical Research Centre of Psychiatry and Neurology n.a. V.M. Bekhterev of MoH of RFSankt-peterburg, Vladimirskaya Oblast’Site status: Not listed — confirm with the team
- Saratov regional clinical psychoneurological hospital St SofiiSaratovSite status: Not listed — confirm with the team
- Stavropol Regional Psychiatry Hospital #2StavropolSite status: Not listed — confirm with the team
- Tomsk National Scientific Medical Center of Russian Academy of SciencesTomskSite status: Not listed — confirm with the team
Ukraine · 6 sites
- Communal Non-Commercial Enterprise of Kharkiv RC Regional clinical psychiatric hospital #3Kharkiv, Kharkiv GovernorateSite status: Not listed — confirm with the team
- Public NPE Kherson Regional Institution of Mental Care of Kherson RCKherson, Kherson GovernorateSite status: Not listed — confirm with the team
- Kyiv Medical Regional Union PsychiatryKylv, KIEV GovernorateSite status: Not listed — confirm with the team
- Communal Non-Commercial Enterprise Cherkasy Regional Psychiatric Hospital of Cherkasy RCSmila, KIEV GovernorateSite status: Not listed — confirm with the team
- Communal NPE Vinnytsia Reg. Clin. Psychoneurolog. Hosp. n.a. O.I. Yushchenko of Vinnytsia RCVinnytsia, Podolia GovernorateSite status: Not listed — confirm with the team
- Poltava Regional Psychiatry HospitalPoltava, Poltava GovernorateSite status: Not listed — confirm with the team
United States · 24 sites
- Woodland International Research Group Inc.Little Rock, ArkansasSite status: Not listed — confirm with the team
- CITrials, Inc.Bellflower, CaliforniaSite status: Not listed — confirm with the team
- ProScience Research GroupCulver City, CaliforniaSite status: Not listed — confirm with the team
- Collaborative Neuroscience Network, Inc.Garden Grove, CaliforniaSite status: Not listed — confirm with the team
- California Clinical Trials Medical Group managed by ParexelGlendale, CaliforniaSite status: Not listed — confirm with the team
- Synergy San DiegoLemon Grove, CaliforniaSite status: Not listed — confirm with the team
- NRC Research InstituteOrange, CaliforniaSite status: Not listed — confirm with the team
- ASCLEPES Research CentersPanorama City, CaliforniaSite status: Not listed — confirm with the team
- CNRI - Los Angeles, LLCPico Rivera, CaliforniaSite status: Not listed — confirm with the team
- CITrials, Inc.Riverside, CaliforniaSite status: Not listed — confirm with the team
- California Neuropsychopharmacology Clinical Research Institute, LLCSan Diego, CaliforniaSite status: Not listed — confirm with the team
- Artemis Institute For Clinical Research LLC - San Diego - ClinEdge - PPDSSan Diego, CaliforniaSite status: Not listed — confirm with the team
- Schuster Medical Research InstituteSherman Oaks, CaliforniaSite status: Not listed — confirm with the team
- Galiz Research, LLCHialeah, FloridaSite status: Not listed — confirm with the team
- Innovative Clinical Research, Inc.Lauderhill, FloridaSite status: Not listed — confirm with the team
- Premier Clinical Research Institute - Miami - BTC - PPDSMiami, FloridaSite status: Not listed — confirm with the team
- Research Centers of America - ERGOakland Park, FloridaSite status: Not listed — confirm with the team
- Atlanta Center For Medical ResearchAtlanta, GeorgiaSite status: Not listed — confirm with the team
- Uptown Research InstituteChicago, IllinoisSite status: Not listed — confirm with the team
- CBH Health LLCGaithersburg, MarylandSite status: Not listed — confirm with the team
- Neuro-Behavioral Clinical Research, Inc.Canton, OhioSite status: Not listed — confirm with the team
- Midwest Clinical Research Center - ERG - PPDSDayton, OhioSite status: Not listed — confirm with the team
- Community Clinical Research Inc.Austin, TexasSite status: Not listed — confirm with the team
- Pillar Clinical Research LLCGarland, TexasSite status: Not listed — confirm with the team
Key information made simple
What is this study testing?
This study is testing whether RO6889450 may be useful for adults experiencing schizophrenia.
What would participation involve?
Participants may receive RO6889450, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Japan, in Russia, and in Ukraine.
Who is it mainly for?
This study appears to be mainly for adults with schizophrenia.
What should you check before joining?
Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.
Your next step
Study sites are listed in the registry. Recruitment status can differ between sites. Ask the research team to confirm the location, any in-person visits, time commitment, costs or compensation, and participation criteria.
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
Study start dateStarted: September 8, 2020
- Recruitment status
- Completed
- Enrollment listed in the registry
- 287
- Sponsor
- Hoffmann-La Roche
- Sponsor type
- Unknown or unclear
- Study type
- Drug
- Intervention type
- Medication / drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States, Japan, Russia, ...
- Age range
- From 18 Years to 45 Years
- Official registry ID
- NCT04512066
- Official title
- A Phase II, Multi-Center, Randomized, Double-Blind, Parallel Group, Placebo-Controlled Trial of the Efficacy and the Safety of RO6889450 (Ralmitaront) vs Placebo in Patients With an Acute Exacerbation of Schizophrenia or Schizoaffective Disorder
- Official source
- Official registry link
Want help reviewing this study?
Study ID: NCT04512066. We help you review the study, but cannot decide medical eligibility.
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with schizophrenia. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving RO6889450, Placebo, Risperidone. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.
Who might this study be for?
This study may concern people with schizophrenia; age range: From 18 Years to 45 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Hoffmann-La Roche, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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