Key information made simple
This summary needs review. Please check the official study record and contact the research team for details.
CompletedNCT04513912
Seltorexant 20 mg for depression
This study is completed in the United States, in Canada, in the United Kingdom, .... It is testing Seltorexant 20 mg for depression.
DepressionDrugFrom 18 Years to 74 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Then choose your country and confirm availability with each study site.
Check the study details
Check the official source, then confirm these points with the research team.
View official study record (opens in a new tab)
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
Study start dateStarted: September 15, 2020
- Recruitment status
- Completed
- Enrollment listed in the registry
- 757
- Sponsor
- Janssen Research & Development, LLC
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- Medication / drug
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
- Locations
- United States, Canada, United Kingdom, ...
- Age range
- From 18 Years to 74 Years
- Official registry ID
- NCT04513912
- Official title
- Double-Blind, Randomized, Parallel-Group Study With Quetiapine Extended Release as Comparator to Evaluate the Efficacy and Safety of Seltorexant 20 mg as Adjunctive Therapy to Antidepressants in Adult and Elderly Patients With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
View official study record (opens in a new tab)The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Argentina · 11 sites
- CENydET - Centro Neurobiologico y de Stress TraumaticoBuenos AiresSite status: Not listed — confirm with the team
- Hospital ItalianoBuenos AiresSite status: Not listed — confirm with the team
- FunDaMosBuenos AiresSite status: Not listed — confirm with the team
- Hospital FleniCiudad Autonoma Buenos AiresSite status: Not listed — confirm with the team
- Fundacion LennoxCórdobaSite status: Not listed — confirm with the team
- Instituto Privado KremerCórdobaSite status: Not listed — confirm with the team
- Centro Medico LuquezCórdobaSite status: Not listed — confirm with the team
- CENPIALa PlataSite status: Not listed — confirm with the team
- Clinica Privada de Salud Mental Santa Teresa de ÁvilaLa PlataSite status: Not listed — confirm with the team
- CENAINMendozaSite status: Not listed — confirm with the team
- Clinica Mayo de UMCBSan Miguel de TucumánSite status: Not listed — confirm with the team
Belgium · 2 sites
- AZ Sint-LucasBrugesSite status: Not listed — confirm with the team
- AZ NikolaasSint-NiklaasSite status: Not listed — confirm with the team
Bulgaria · 11 sites
- Medical Center Medconsult-PlevenPlevenSite status: Not listed — confirm with the team
- MC 'Hipokrat - N', EOODPlovdivSite status: Not listed — confirm with the team
- Mental Health Center - RousseRousseSite status: Not listed — confirm with the team
- Medical Center St. NaumSofiaSite status: Not listed — confirm with the team
- Medical Center Intermedica, OODSofiaSite status: Not listed — confirm with the team
- MC 'Synexus Sofia' EOODSofiaSite status: Not listed — confirm with the team
- MC 'Synexus Sofia' EOODStara ZagoraSite status: Not listed — confirm with the team
- UMHAT Prof. Dr. St. Kirkovich ADStara ZagoraSite status: Not listed — confirm with the team
- State Psychiatric Hospital - Tzarev BrodTzarev BrodSite status: Not listed — confirm with the team
- Diagnostic Consulting Center Mladost - M VarnaVarnaSite status: Not listed — confirm with the team
- Mental Health Center - Veliko Tarnovo EOODVeliko TarnovoSite status: Not listed — confirm with the team
Canada · 3 sites
- A.K. Munshi Medical Inc.Sydney, Nova ScotiaSite status: Not listed — confirm with the team
- Canadian Phase OnwardToronto, OntarioSite status: Not listed — confirm with the team
- Clinique Force Medic (GCP Trials)Montreal, QuebecSite status: Not listed — confirm with the team
Czechia · 7 sites
- Psychiatricka ambulance Saint Anne s.r.o.BrnoSite status: Not listed — confirm with the team
- NeuropsychiatrieHK, s.r.o.Hradec KrálovéSite status: Not listed — confirm with the team
- A Shine S R OPilsenSite status: Not listed — confirm with the team
- Clintrial s r oPragueSite status: Not listed — confirm with the team
- AD71 s.r.o.PragueSite status: Not listed — confirm with the team
- NeuropsychiatrieHK, s.r.o.PragueSite status: Not listed — confirm with the team
- Institut Neuropsychiatricke pecePragueSite status: Not listed — confirm with the team
Latvia · 4 sites
- The Mental Hospital of Jelgava Ģintermuiža - PsychiatryJelgavaSite status: Not listed — confirm with the team
- L. Keruze Practice in PsychiatryLiepājaSite status: Not listed — confirm with the team
- Hospital of RezekneOutpatient Centre of PsychiatrySite status: Not listed — confirm with the team
- Riga Centre of Psychiatry and NarcologyRigaSite status: Not listed — confirm with the team
Lithuania · 8 sites
- Kaunas Silainiu Outpatient Clinic, Public InstitutionKaunasSite status: Not listed — confirm with the team
- Republic Kaunas HospitalKaunasSite status: Not listed — confirm with the team
- Romuvos Klinika, JSCKaunasSite status: Not listed — confirm with the team
- Hospital of Lithuanian University of Health Sciences Kaunas ClinicsKaunasSite status: Not listed — confirm with the team
- Medical Center Puriena JSCŠilutėSite status: Not listed — confirm with the team
- Zirmunai Mental Health Center, Public InstitutionVilniusSite status: Not listed — confirm with the team
- Antakalnis Psychiatric Consultation Centre, Public InstitutionVilniusSite status: Not listed — confirm with the team
- Vilnius Mental Health CenterVilniusSite status: Not listed — confirm with the team
Malaysia · 4 sites
- Hospital Raja Permaisuri BainunIpohSite status: Not listed — confirm with the team
- Hospital PermaiJohor BahruSite status: Not listed — confirm with the team
- Hospital Pulau PinangPulau PinangSite status: Not listed — confirm with the team
- Hospital Tuanku JaafarSerembanSite status: Not listed — confirm with the team
Poland · 10 sites
- Gabinet Lekarski Psychiatryczny Ireneusz KaczorowskiBełchatówSite status: Not listed — confirm with the team
- Wlokiennicza MED Specjalistyczna Praktyka Lekarska dr n.med. Tomasz MarkowskiBialystokSite status: Not listed — confirm with the team
- Przychodnia Srodmiescie SP. z o.o.BydgoszczSite status: Not listed — confirm with the team
- Centrum Badan Klinicznych PI House sp z o oGdanskSite status: Not listed — confirm with the team
- Specjalistyczna Indywidualna Praktyka LekarskaLodzSite status: Not listed — confirm with the team
- CCBR - Lodz - PLLodzSite status: Not listed — confirm with the team
- Specjalistyczna Praktyka Lekarska Marek DomanskiLublinSite status: Not listed — confirm with the team
- Synexus Polska Sp. z.o.o. Oddzial w PoznaniuPoznanSite status: Not listed — confirm with the team
- Specjalistyczny Osrodek Medycyny Wieku Dojrzalego Sp z o.o.WarsawSite status: Not listed — confirm with the team
- Instytut Psychiatrii I NeurologiiWarsawSite status: Not listed — confirm with the team
Russia · 10 sites
- Engels psychiatric hospitalEngel'sSite status: Not listed — confirm with the team
- Kemerovo Regional Clinical Psychiatric HospitalKemerovoSite status: Not listed — confirm with the team
- GUZ Lipetsk Regional psychoneurological Hospital #1Lipetsk RegionSite status: Not listed — confirm with the team
- JSC Scientific Centre of Personalized MedicineMoscowSite status: Not listed — confirm with the team
- FSI Moscow SRI of Psychiatry of MinzdravsocrazvitiaMoscowSite status: Not listed — confirm with the team
- Moscow Scientific Research Institute of PsychiatryMoscowSite status: Not listed — confirm with the team
- Clinical Psychiatry Hospital n.a. N.N. SolodovnikovOmskSite status: Not listed — confirm with the team
- St-Petersburg Bekhterev Psychoneurological Research InstituteSaint PetersburgSite status: Not listed — confirm with the team
- Klinika StoLet LtdTomskSite status: Not listed — confirm with the team
- Sverdlov Regional Psychiatric Clinical HospitalYekaterinburgSite status: Not listed — confirm with the team
Serbia · 9 sites
- General Hospital Acibadem Bel MedicBelgradeSite status: Not listed — confirm with the team
- General Hospital EuromedikBelgradeSite status: Not listed — confirm with the team
- Institute of Mental Health SerbiaBelgradeSite status: Not listed — confirm with the team
- University Clinical Center of SerbiaBelgradeSite status: Not listed — confirm with the team
- University Clinical Hospital Center Dr Dragisa Misovic- DediBelgradeSite status: Not listed — confirm with the team
- Special Neuropsychiatric Hospital KovinKovinSite status: Not listed — confirm with the team
- University Clinical Center KragujevacKragujevacSite status: Not listed — confirm with the team
- Clinical Center NisNišSite status: Not listed — confirm with the team
- Specialized Hospital for Neuropsychiatric Diseases Sveti VraceviNovi KneževacSite status: Not listed — confirm with the team
Slovakia · 8 sites
- Psychomed-Svatosavsky, s.r.o.Banská BystricaSite status: Not listed — confirm with the team
- Nemocnica s poliklinikou Prievidza so sidlom v BojniciachBojniceSite status: Not listed — confirm with the team
- Epamed sroKošiceSite status: Not listed — confirm with the team
- Liptovska Nemocnica S Poliklinikou Mudr. Ivana StodoluLiptovský MikulášSite status: Not listed — confirm with the team
- Psychiatricka Ambulancia Psycholine S.R.O.Rimavská SobotaSite status: Not listed — confirm with the team
- FN TrencinTrenčínSite status: Not listed — confirm with the team
- Pro mente sana s.r.o.TrenčínSite status: Not listed — confirm with the team
- Fakultna nemocnica s poliklinikou v ZilineŽilinaSite status: Not listed — confirm with the team
Ukraine · 8 sites
- MNCE of Kyiv RC Regional Psychiatric and Narcological Medical AssociationHlevakhaSite status: Not listed — confirm with the team
- Mnpe of Kharkiv Regional Council 'Regional Clinical Psychiatric Hospital #3'KharkivSite status: Not listed — confirm with the team
- Kyiv Territorial Medical Incorporation 'Psychiatry'KyivSite status: Not listed — confirm with the team
- Railway Clinical Hospital #1 of Kiev Railway station of DTGO 'South-Western Railway'KyivSite status: Not listed — confirm with the team
- Medical Center Health and HappyKyivSite status: Not listed — confirm with the team
- Mnpe 'Regional Clinical Psychiatric Hospital of Kirovohrad Regional Council'NoveSite status: Not listed — confirm with the team
- Ternopil RCCPH Depts of Psychiatry #2 (m) & Psychiatry #4 (f) Ternopil I.Ya. Gorbachevskyi SMUTernopilSite status: Not listed — confirm with the team
- Zaporizhzhia Regional Clinical HospitalZaporizhzhyaSite status: Not listed — confirm with the team
United Kingdom · 5 sites
- Kingsway HospitalDerbySite status: Not listed — confirm with the team
- SynexusGreater ManchesterSite status: Not listed — confirm with the team
- Garden Valleys Resource CentreHarrogateSite status: Not listed — confirm with the team
- Kings College Hospital NHS TrustLondonSite status: Not listed — confirm with the team
- Cornwall Partnership Foundation TrustRedruthSite status: Not listed — confirm with the team
United States · 75 sites
- University of Alabama at BirminghamBirmingham, AlabamaSite status: Not listed — confirm with the team
- SW Biomedical Research LLCTucson, ArizonaSite status: Not listed — confirm with the team
- Proscience Research GroupCulver City, CaliforniaSite status: Not listed — confirm with the team
- Pharmacology Research InstituteEncino, CaliforniaSite status: Not listed — confirm with the team
- Collaborative NeuroScience NetworkGarden Grove, CaliforniaSite status: Not listed — confirm with the team
- Collaborative NeuroScience NetworkLong Beach, CaliforniaSite status: Not listed — confirm with the team
- Pharmacology Research InstituteLos Alamitos, CaliforniaSite status: Not listed — confirm with the team
- CalNeuro ResearchLos Angeles, CaliforniaSite status: Not listed — confirm with the team
- Pharmacology Research InstituteNewport Beach, CaliforniaSite status: Not listed — confirm with the team
- NRC Research InstituteOrange, CaliforniaSite status: Not listed — confirm with the team
- Pacific Neuropsychiatric SpecialistsOrange, CaliforniaSite status: Not listed — confirm with the team
- CNRI-Los Angeles, LLCPico Rivera, CaliforniaSite status: Not listed — confirm with the team
- Prospective Research Innovations IncRancho Cucamonga, CaliforniaSite status: Not listed — confirm with the team
- Anderson Clinical ResearchRedlands, CaliforniaSite status: Not listed — confirm with the team
- University of California at San DiegoSan Diego, CaliforniaSite status: Not listed — confirm with the team
- National Research InstituteSanta Ana, CaliforniaSite status: Not listed — confirm with the team
- CI TrialsSanta Ana, CaliforniaSite status: Not listed — confirm with the team
- CMB Clinical TrialsSantee, CaliforniaSite status: Not listed — confirm with the team
- Schuster Medical Research InstituteSherman Oaks, CaliforniaSite status: Not listed — confirm with the team
- Pacific Clinical Research Medical GroupUpland, CaliforniaSite status: Not listed — confirm with the team
- Hartford HospitalHartford, ConnecticutSite status: Not listed — confirm with the team
- Moonshine Research Center, IncDoral, FloridaSite status: Not listed — confirm with the team
- Velocity Clinical Research, Hallandale BeachHallandale, FloridaSite status: Not listed — confirm with the team
- Indago Research & Health Center IncHialeah, FloridaSite status: Not listed — confirm with the team
- New Life Medical Research Center, Inc.Hialeah, FloridaSite status: Not listed — confirm with the team
- Amedica Research Institute IncHialeah, FloridaSite status: Not listed — confirm with the team
- Meridien ResearchLakeland, FloridaSite status: Not listed — confirm with the team
- Premier Clinical ResearchMiami, FloridaSite status: Not listed — confirm with the team
- Global Medical InstitutesMiami, FloridaSite status: Not listed — confirm with the team
- Miami Jewish Health SystemMiami, FloridaSite status: Not listed — confirm with the team
- Clinical Neuroscience SolutionsOrlando, FloridaSite status: Not listed — confirm with the team
- Synexus Research OrlandoOrlando, FloridaSite status: Not listed — confirm with the team
- University of South FloridaTampa, FloridaSite status: Not listed — confirm with the team
- Compass Research LLC-Bioclinica ResearchThe Villages, FloridaSite status: Not listed — confirm with the team
- Synexus Clinical Research US IncAtlanta, GeorgiaSite status: Not listed — confirm with the team
- Atlanta Center for Medical ResearchAtlanta, GeorgiaSite status: Not listed — confirm with the team
- iResearch Atlanta LLCDecatur, GeorgiaSite status: Not listed — confirm with the team
- Psych Atlanta, P.C.Marietta, GeorgiaSite status: Not listed — confirm with the team
- Chicago Research CenterChicago, IllinoisSite status: Not listed — confirm with the team
- Capstone Clinical ResearchLibertyville, IllinoisSite status: Not listed — confirm with the team
- Alexian Brothers Health SystemLisle, IllinoisSite status: Not listed — confirm with the team
- Baber Research GroupNaperville, IllinoisSite status: Not listed — confirm with the team
- Lemah Creek Clinical ResearchOakbrook Terrace, IllinoisSite status: Not listed — confirm with the team
- Ascension via Christi ResearchWichita, KansasSite status: Not listed — confirm with the team
- Riverstar ResearchNew Orleans, LouisianaSite status: Not listed — confirm with the team
- Pharmasite Research, Inc.Baltimore, MarylandSite status: Not listed — confirm with the team
- BTC of New BedfordNew Bedford, MassachusettsSite status: Not listed — confirm with the team
- Boston Clinical Trials & Medical ResearchRoslindale, MassachusettsSite status: Not listed — confirm with the team
- Psychiatric Care and Research Center (PCRC)O'Fallon, MissouriSite status: Not listed — confirm with the team
- Bio Behavioral HealthToms River, New JerseySite status: Not listed — confirm with the team
- SPRI Clinical Trials, LLCBrooklyn, New YorkSite status: Not listed — confirm with the team
- Fieve Clinical Research IncNew York, New YorkSite status: Not listed — confirm with the team
- The Medical Research Network, LLCNew York, New YorkSite status: Not listed — confirm with the team
- Finger Lakes Clinical ResearchRochester, New YorkSite status: Not listed — confirm with the team
- Richmond Behavioral AssociatesStaten Island, New YorkSite status: Not listed — confirm with the team
- Velocity Clinical Research, Inc.Durham, North CarolinaSite status: Not listed — confirm with the team
- University of Cincinnati, Dept of Psychiatry & Behavioral NeuroscienceCincinnati, OhioSite status: Not listed — confirm with the team
- Midwest Clinical Research CenterDayton, OhioSite status: Not listed — confirm with the team
- Neuro Behavioral Clinical ResearchNorth Canton, OhioSite status: Not listed — confirm with the team
- Sooner Clinical ResearchOklahoma City, OklahomaSite status: Not listed — confirm with the team
- Paradigm Research Professionals, LLCOklahoma City, OklahomaSite status: Not listed — confirm with the team
- Suburban Research AssociatesPine Hill, PennsylvaniaSite status: Not listed — confirm with the team
- Global Medical InstitutesScranton, PennsylvaniaSite status: Not listed — confirm with the team
- Coastal Carolina Research CenterMt. Pleasant, South CarolinaSite status: Not listed — confirm with the team
- West Houston Clinical Research ServiceBellaire, TexasSite status: Not listed — confirm with the team
- North Texas Clinical TrialsFort Worth, TexasSite status: Not listed — confirm with the team
- Hawkins Psychiatry, PCMansfield, TexasSite status: Not listed — confirm with the team
- Family Psychiatry of The WoodlandsThe Woodlands, TexasSite status: Not listed — confirm with the team
- Grayline Research CenterWichita Falls, TexasSite status: Not listed — confirm with the team
- Alpine Research OrganizationClinton, UtahSite status: Not listed — confirm with the team
- Cedar Clinical ResearchDraper, UtahSite status: Not listed — confirm with the team
- University of VirginiaCharlottesville, VirginiaSite status: Not listed — confirm with the team
- Northwest Clinical Research CenterBellevue, WashingtonSite status: Not listed — confirm with the team
- Core Clinical ResearchEverett, WashingtonSite status: Not listed — confirm with the team
- Cary J. Kohlenberg, MD, SC, dba, IPC Research.Waukesha, WisconsinSite status: Not listed — confirm with the team
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT04513912. We help you review the study, but cannot decide medical eligibility.
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving Seltorexant, Matching placebo to Seltorexant, Quetiapine XR, Matching placebo to Quetiapine XR. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 74 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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