Key information made simple
This summary needs review. Please check the official study record and contact the research team for details.
CompletedNCT04533529
Seltorexant 20 mg for depression
This study is completed in the United States, in Brazil, in Bulgaria, .... It is testing Seltorexant 20 mg for depression.
DepressionDrugFrom 18 Years to 74 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Then choose your country and confirm availability with each study site.
Check the study details
Check the official source, then confirm these points with the research team.
View official study record (opens in a new tab)
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
Study start dateStarted: September 16, 2020
- Recruitment status
- Completed
- Enrollment listed in the registry
- 588
- Sponsor
- Janssen Research & Development, LLC
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- Medication / drug
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
- Locations
- United States, Brazil, Bulgaria, ...
- Age range
- From 18 Years to 74 Years
- Official registry ID
- NCT04533529
- Official title
- A Multicenter, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled, Study to Evaluate the Efficacy and Safety of Seltorexant 20 mg as Adjunctive Therapy to Antidepressants in Adult and Elderly Patients With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy and an Open-labeled Long-term Safety Extension Treatment With Seltorexant
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
View official study record (opens in a new tab)The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Brazil · 8 sites
- CPN - Centro de Pesquisa em Neurociências LtdaBelo HorizonteSite status: Not listed — confirm with the team
- CCB Centro Cardiologico de Brasilia Ltda - CCB CardiologiaBrasíliaSite status: Not listed — confirm with the team
- Instituto de Neurologia de CuritibaCuritibaSite status: Not listed — confirm with the team
- Universidade Federal do Ceara Hospital Universitario Walter CantidioFortalezaSite status: Not listed — confirm with the team
- Instituto Mederi de Pesquisa e SaudePasso FundoSite status: Not listed — confirm with the team
- Ruschel Medicina e Pesquisa Clínica LtdaRio de JaneiroSite status: Not listed — confirm with the team
- SPDM - Associacao Paulista para o Desenvolvimento da Medicina - Hospital Sao PauloSão PauloSite status: Not listed — confirm with the team
- Instituto Bairral de PsiquiatriaSão PauloSite status: Not listed — confirm with the team
Bulgaria · 11 sites
- Mental Health Center Prof. Dr. Ivan TemkovBurgasSite status: Not listed — confirm with the team
- Ambulatory for Individual Practice for Specialized Medical Care in Psychiatry Dr. Ivo Natsov ETCherven BryagSite status: Not listed — confirm with the team
- State Psychiatric Hospital KardzhaliKardzhaliSite status: Not listed — confirm with the team
- Medical center Spectar - Plovdiv EOODPlovdivSite status: Not listed — confirm with the team
- UMHAT 'Sv. Georgi' EADPlovdivSite status: Not listed — confirm with the team
- MHC - Sofia, EOODSlivnitsaSite status: Not listed — confirm with the team
- Medical Center St. NaumSofiaSite status: Not listed — confirm with the team
- DCC 'Sv. Vrach and Sv. Sv. Kuzma and Damyan', OODSofiaSite status: Not listed — confirm with the team
- Medical Center Intermedica, OODSofiaSite status: Not listed — confirm with the team
- Medical center - VAS OODTargovishteSite status: Not listed — confirm with the team
- Mental Health Center - Vratsa EOODVratsaSite status: Not listed — confirm with the team
Colombia · 5 sites
- Centro de Investigaciones y Proyectos en Neurociencias CIPNABarranquillaSite status: Not listed — confirm with the team
- HOMO - ESE Hospital Mental de AntioquiaBelloSite status: Not listed — confirm with the team
- Centro de Investigaciones del Sistema Nervioso Grupo Cisne Ltda.BogotáSite status: Not listed — confirm with the team
- Fundacion Centro de Investigacion Clinica CICMedellínSite status: Not listed — confirm with the team
- Psynapsis Salud Mental S.A.PereiraSite status: Not listed — confirm with the team
Czechia · 5 sites
- BRAIN-SOULTHERAPY s.r.o.KladnoSite status: Not listed — confirm with the team
- Neuroterapie KH S R OKutná HoraSite status: Not listed — confirm with the team
- A Shine S R OPilsenSite status: Not listed — confirm with the team
- Clintrial s r oPragueSite status: Not listed — confirm with the team
- Medical Services Prague S R OPragueSite status: Not listed — confirm with the team
Mexico · 3 sites
- Iecsi S.C.MonterreySite status: Not listed — confirm with the team
- CRI Centro Regiomontano de Investigacion SCNuevo LeónSite status: Not listed — confirm with the team
- Bind Investigaciones S.C.San Luis Potosí CitySite status: Not listed — confirm with the team
Russia · 8 sites
- Psychoneurological Dispensary of Frunzensky DistrictSaint PetersburgSite status: Not listed — confirm with the team
- SPb SBIH 'City Psychoneurological Dispensary # 7 (With Inpatient Facilities)'Saint PetersburgSite status: Not listed — confirm with the team
- City Psychiatric Hospital of St. Nikolay ChudotvoretsSaint PetersburgSite status: Not listed — confirm with the team
- Bekhterev Psychoneurological Research InstituteSaint PetersburgSite status: Not listed — confirm with the team
- St-Petersburg Bekhterev Psychoneurological Research InstituteSaint PetersburgSite status: Not listed — confirm with the team
- Psychoneurological dispensary 1Saint PetersburgSite status: Not listed — confirm with the team
- Stavropol Region Psychiatric Hospital #2StavropolSite status: Not listed — confirm with the team
- Yaroslavl Region Clinical Psychiatric HospitalYaroslavlSite status: Not listed — confirm with the team
South Africa · 8 sites
- Farmovs Pty LtdBloemfonteinSite status: Not listed — confirm with the team
- Iatros InternationalBloemfonteinSite status: Not listed — confirm with the team
- Cape Town Clinical Research CentreCape TownSite status: Not listed — confirm with the team
- Flexivest 14 ResearchCape TownSite status: Not listed — confirm with the team
- DJW ResearchKrugersdorpSite status: Not listed — confirm with the team
- Stanza Clinical Research Centre : MamelodiMamelodi EastSite status: Not listed — confirm with the team
- Synexus WatermeyerPretoriaSite status: Not listed — confirm with the team
- Somerset West Clinical Research UnitStrandSite status: Not listed — confirm with the team
Spain · 10 sites
- Institucion Hosp Hestia PalauBarcelonaSite status: Not listed — confirm with the team
- Hosp Univ Vall D HebronBarcelonaSite status: Not listed — confirm with the team
- Hosp. Univ. de BasurtoBilbaoSite status: Not listed — confirm with the team
- Hosp. Univ. Ramon Y CajalMadridSite status: Not listed — confirm with the team
- Hosp. Univ. La PazMadridSite status: Not listed — confirm with the team
- Centro Salud Mental La CorredoriaOviedoSite status: Not listed — confirm with the team
- Clinica Univ. de NavarraPamplonaSite status: Not listed — confirm with the team
- Corporacio Sanitari Parc TauliSabadellSite status: Not listed — confirm with the team
- Centro de salud San Juan - IBSALSalamancaSite status: Not listed — confirm with the team
- Hosp. Prov. de ZamoraZamoraSite status: Not listed — confirm with the team
Sweden · 6 sites
- Affecta PskyiatrimottagningHalmstadSite status: Not listed — confirm with the team
- PharmaSite HelsingborgHelsingborgSite status: Not listed — confirm with the team
- ProbarE i Lund ABLundSite status: Not listed — confirm with the team
- PharmaSiteMalmöSite status: Not listed — confirm with the team
- LäkarmottagningenSkövdeSite status: Not listed — confirm with the team
- ProbarE i SolnaStockholmSite status: Not listed — confirm with the team
Taiwan · 7 sites
- Chang-Gung Memorial Hospital-KeelungKeelungSite status: Not listed — confirm with the team
- National Taiwan University HospitalTaipeiSite status: Not listed — confirm with the team
- Mackay Memorial HospitalTaipeiSite status: Not listed — confirm with the team
- Taipei Medical UniversityTaipeiSite status: Not listed — confirm with the team
- Cheng Hsin General HospitalTaipeiSite status: Not listed — confirm with the team
- Taipei Veterans General HospitalTaipeiSite status: Not listed — confirm with the team
- Chang Gung Memorial Hospital- LinkouTaoyuan CountySite status: Not listed — confirm with the team
United States · 51 sites
- Advanced Research Center IncAnaheim, CaliforniaSite status: Not listed — confirm with the team
- SynexusCerritos, CaliforniaSite status: Not listed — confirm with the team
- Irvine Clinical ResearchIrvine, CaliforniaSite status: Not listed — confirm with the team
- Omega Clinical Trials LLCLa Habra, CaliforniaSite status: Not listed — confirm with the team
- Synergy EastLemon Grove, CaliforniaSite status: Not listed — confirm with the team
- Semel Institute for Neuroscience and Human BehaviorLos Angeles, CaliforniaSite status: Not listed — confirm with the team
- Catalina Research InstituteMontclair, CaliforniaSite status: Not listed — confirm with the team
- Pacific Research PartnersOakland, CaliforniaSite status: Not listed — confirm with the team
- North County Clinical ResearchOceanside, CaliforniaSite status: Not listed — confirm with the team
- Syrentis Clinical ResearchSanta Ana, CaliforniaSite status: Not listed — confirm with the team
- Viking Pharmaceutical Trials Inc. dba Viking Clinical ResearchTemecula, CaliforniaSite status: Not listed — confirm with the team
- Connecticut Clinical Trials LLCCromwell, ConnecticutSite status: Not listed — confirm with the team
- University of Connecticut Health CenterFarmington, ConnecticutSite status: Not listed — confirm with the team
- Sarkis Clinical TrialsGainesville, FloridaSite status: Not listed — confirm with the team
- Clinical NeuroScience Solutions IncJacksonville, FloridaSite status: Not listed — confirm with the team
- Pharmax Research Clinic IncMiami, FloridaSite status: Not listed — confirm with the team
- Medical Research Center of Miami II IncMiami, FloridaSite status: Not listed — confirm with the team
- Phoenix Medical Research, Inc.Miami, FloridaSite status: Not listed — confirm with the team
- Galiz ResearchMiami Springs, FloridaSite status: Not listed — confirm with the team
- Bravo Health Care CenterNorth Bay Village, FloridaSite status: Not listed — confirm with the team
- APG Research LLCOrlando, FloridaSite status: Not listed — confirm with the team
- Combined Research OrlandoOrlando, FloridaSite status: Not listed — confirm with the team
- Nova Psychiatry INCOrlando, FloridaSite status: Not listed — confirm with the team
- Revive Research InstituteElgin, IllinoisSite status: Not listed — confirm with the team
- Joliet Center for Clinical ResearchJoliet, IllinoisSite status: Not listed — confirm with the team
- Baber Research GroupNaperville, IllinoisSite status: Not listed — confirm with the team
- American Medical Research, Inc.Oak Brook, IllinoisSite status: Not listed — confirm with the team
- Southern Illinois University School of MedicineSpringfield, IllinoisSite status: Not listed — confirm with the team
- Louisiana Clinical ResearchShreveport, LouisianaSite status: Not listed — confirm with the team
- Adams ClinicalWatertown, MassachusettsSite status: Not listed — confirm with the team
- Neurobehavioral Medicine GroupBloomfield Hills, MichiganSite status: Not listed — confirm with the team
- Midwest Research Group - St. Charles Psychiatric AssociatesSaint Charles, MissouriSite status: Not listed — confirm with the team
- Mid-America Clinical Research, LLCSt Louis, MissouriSite status: Not listed — confirm with the team
- PsychCare Consultants ResearchSt Louis, MissouriSite status: Not listed — confirm with the team
- Premier Psychiatric Research Institute, LLCLincoln, NebraskaSite status: Not listed — confirm with the team
- Altea Research InstituteLas Vegas, NevadaSite status: Not listed — confirm with the team
- Hassman Research Institute, LLC.Berlin, New JerseySite status: Not listed — confirm with the team
- Synexus Clinical Research US IncJamaica, New YorkSite status: Not listed — confirm with the team
- Bioscience Research LLCMount Kisco, New YorkSite status: Not listed — confirm with the team
- Haidar Almhana NiedingAvon Lake, OhioSite status: Not listed — confirm with the team
- The Ohio State UniversityColumbus, OhioSite status: Not listed — confirm with the team
- Lindner Center of HopeMason, OhioSite status: Not listed — confirm with the team
- Oklahoma Clinical Research CenterOklahoma City, OklahomaSite status: Not listed — confirm with the team
- Lehigh Center for Clinical ResearchAllentown, PennsylvaniaSite status: Not listed — confirm with the team
- University of Pennsylvania - Perelman School of MedicinePhiladelphia, PennsylvaniaSite status: Not listed — confirm with the team
- Relaro Medical TrialsDallas, TexasSite status: Not listed — confirm with the team
- North Texas Clinical TrialsFort Worth, TexasSite status: Not listed — confirm with the team
- Baylor College of MedicineHouston, TexasSite status: Not listed — confirm with the team
- Red Oak Psychiatry AssociatesHouston, TexasSite status: Not listed — confirm with the team
- Alpine Research OrganizationClinton, UtahSite status: Not listed — confirm with the team
- Green Mountain Research InstituteRutland, VermontSite status: Not listed — confirm with the team
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT04533529. We help you review the study, but cannot decide medical eligibility.
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving Seltorexant, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 74 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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