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TerminatedNCT04663321

Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)

This study evaluates the safety and effectiveness of MK-1942 for people with depression.

Medication studyAges 18–65United States
The study in practice

Understand this study

What is this study about?

This study evaluates the safety and effectiveness of MK-1942 for people with depression.

Who could participate?

This study is for people with depression. Listed age limits: 18 years to 65 years. Other eligibility criteria apply.

Listed locations
Birmingham, United States · Little Rock, United States and 41 more locationsSee all locations and recruitment
Activities
Medication described in the protocol · Medication and placebo comparator listed across study groups
Compensation
Payment and expense reimbursement have not been verified.

What to know before participating

A point to clarify

This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?

Study clarity

Things to check before joining

Study start dateStarted: May 20, 2021
Recruitment status
Terminated
Enrollment listed in the registry
99
Sponsor
Merck Sharp & Dohme LLC
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States
Age range
From 18 Years to 65 Years
Official registry ID
NCT04663321
Official title
Show the full official title

A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

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Study ID: NCT04663321. We help you review the study, but cannot decide medical eligibility.

Recruitment & locations

Terminated

Birmingham · Little Rock · Bellflower

40 more locations
  • Colton
  • Garden Grove
  • Santa Ana
  • Hartford
  • Fort Myers
  • Hallandale
  • Jacksonville
  • Lauderhill
  • Miami
  • Naples
  • Orlando
  • Tampa
  • Winter Park
  • Atlanta
  • Decatur
  • Marietta
  • Savannah
  • Chicago
  • Gaithersburg
  • Boston
  • Ann Arbor
  • Las Vegas
  • Berlin
  • Princeton
  • Albuquerque
  • New York
  • Staten Island
  • Charlotte
  • Hickory
  • North Canton
  • Oklahoma City
  • Media
  • Philadelphia
  • Plymouth Meeting
  • Houston
  • Plano
  • Draper
  • Woodstock
  • Bellevue
  • Everett

A listed location does not confirm current availability.

FAQ

Questions about this study

What is this study about?

This study evaluates the safety and effectiveness of MK-1942 for people with depression.

Who is behind this study?

The study sponsor is Merck Sharp & Dohme LLC.

Does this study involve medication?

Yes. The study involves medication, including MK-1942 and Placebo.

Who can participate?

This study is for people with depression. Listed age limits: 18 years to 65 years. Other eligibility criteria apply.

Is this study still recruiting?

The registry lists this study as terminated.

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