Key information made simple
This summary needs review. Please check the official study record and contact the research team for details.
TerminatedNCT04663321
MK-1942 Added to Stable Antidepressant Therapy for treatment-resistant depression
This study was terminated in the United States. It is testing MK-1942 Added to Stable Antidepressant Therapy for treatment-resistant depression.
DepressionDrugFrom 18 Years to 65 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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Check the study details
Check the official source, then confirm these points with the research team.
View official study record (opens in a new tab)
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
Study start dateStarted: May 20, 2021
- Recruitment status
- Terminated
- Enrollment listed in the registry
- 99
- Sponsor
- Merck Sharp & Dohme LLC
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- Medication / drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- From 18 Years to 65 Years
- Official registry ID
- NCT04663321
- Official title
- A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
View official study record (opens in a new tab)The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
United States · 45 sites
- University of Alabama at Birmingham - School of Medicine-Psychiatry ( Site 1073)Birmingham, AlabamaSite status: Not listed — confirm with the team
- Preferred Research Partners ( Site 1079)Little Rock, ArkansasSite status: Not listed — confirm with the team
- Woodland International Research Group ( Site 1017)Little Rock, ArkansasSite status: Not listed — confirm with the team
- CITrials-Outpatient Facility ( Site 1098)Bellflower, CaliforniaSite status: Not listed — confirm with the team
- Axiom Research ( Site 1053)Colton, CaliforniaSite status: Not listed — confirm with the team
- Collaborative Neuroscience Network, LLC. ( Site 1032)Garden Grove, CaliforniaSite status: Not listed — confirm with the team
- CITrials ( Site 1105)Santa Ana, CaliforniaSite status: Not listed — confirm with the team
- Institute of Living ( Site 1061)Hartford, ConnecticutSite status: Not listed — confirm with the team
- Gulfcoast Clinical Research Center ( Site 1110)Fort Myers, FloridaSite status: Not listed — confirm with the team
- Velocity Clinical Research, Hallandale Beach ( Site 1116)Hallandale, FloridaSite status: Not listed — confirm with the team
- Clinical Neuroscience Solutions, Inc. dba CNS Healthcare ( Site 1039)Jacksonville, FloridaSite status: Not listed — confirm with the team
- Innovative Clinical Research ( Site 1044)Lauderhill, FloridaSite status: Not listed — confirm with the team
- Behavioral Clinical Research ( Site 1037)Miami, FloridaSite status: Not listed — confirm with the team
- Aqualane Clinical Research ( Site 1113)Naples, FloridaSite status: Not listed — confirm with the team
- APG RESEARCH, LLC ( Site 1087)Orlando, FloridaSite status: Not listed — confirm with the team
- University of South Florida-Psychiatry and Behavioral Neurosciences ( Site 1093)Tampa, FloridaSite status: Not listed — confirm with the team
- K2 Medical Research - Winter Park ( Site 1115)Winter Park, FloridaSite status: Not listed — confirm with the team
- Atlanta Center for Medical Research ( Site 1022)Atlanta, GeorgiaSite status: Not listed — confirm with the team
- iResearch Atlanta ( Site 1040)Decatur, GeorgiaSite status: Not listed — confirm with the team
- Psych Atlanta ( Site 1108)Marietta, GeorgiaSite status: Not listed — confirm with the team
- iResearch Savannah ( Site 1041)Savannah, GeorgiaSite status: Not listed — confirm with the team
- Ascension Saint Elizabeth ( Site 1003)Chicago, IllinoisSite status: Not listed — confirm with the team
- CBH Health ( Site 1076)Gaithersburg, MarylandSite status: Not listed — confirm with the team
- Boston Clinical Trials ( Site 1028)Boston, MassachusettsSite status: Not listed — confirm with the team
- University of Michigan-Psychiatry ( Site 1051)Ann Arbor, MichiganSite status: Not listed — confirm with the team
- Altea Research ( Site 1018)Las Vegas, NevadaSite status: Not listed — confirm with the team
- Hassman Research Institute ( Site 1036)Berlin, New JerseySite status: Not listed — confirm with the team
- Global Medical Institutes LLC; Princeton Medical Institute ( Site 1049)Princeton, New JerseySite status: Not listed — confirm with the team
- Albuquerque Neuroscience Inc. ( Site 1107)Albuquerque, New MexicoSite status: Not listed — confirm with the team
- Hapworth Research Inc.-Clinical Research Department ( Site 1090)New York, New YorkSite status: Not listed — confirm with the team
- Manhattan Behavioral Medicine ( Site 1096)New York, New YorkSite status: Not listed — confirm with the team
- Richmond Behavioral Associates ( Site 1011)Staten Island, New YorkSite status: Not listed — confirm with the team
- New Hope Clinical Research ( Site 1082)Charlotte, North CarolinaSite status: Not listed — confirm with the team
- Clinical Trials of America, LLC ( Site 1103)Hickory, North CarolinaSite status: Not listed — confirm with the team
- Neuro-Behavioral Clinical Research ( Site 1045)North Canton, OhioSite status: Not listed — confirm with the team
- Paradigm Research Professionals ( Site 1089)Oklahoma City, OklahomaSite status: Not listed — confirm with the team
- Suburban Research Associates-Clinical Research ( Site 1042)Media, PennsylvaniaSite status: Not listed — confirm with the team
- Penn Medicine: University of Pennsylvania Health System-Mood Disorders Treatment and Research ProgaPhiladelphia, PennsylvaniaSite status: Not listed — confirm with the team
- Keystone Clinical Studies ( Site 1031)Plymouth Meeting, PennsylvaniaSite status: Not listed — confirm with the team
- Baylor College of Medicine ( Site 1019)Houston, TexasSite status: Not listed — confirm with the team
- AIM Trials, LLC ( Site 1111)Plano, TexasSite status: Not listed — confirm with the team
- Cedar Clinical Research ( Site 1023)Draper, UtahSite status: Not listed — confirm with the team
- Woodstock Research Center ( Site 1084)Woodstock, VermontSite status: Not listed — confirm with the team
- Northwest Clinical Research Center ( Site 1112)Bellevue, WashingtonSite status: Not listed — confirm with the team
- Core Clinical Research ( Site 1081)Everett, WashingtonSite status: Not listed — confirm with the team
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT04663321. We help you review the study, but cannot decide medical eligibility.
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving MK-1942, Placebo. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 65 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Merck Sharp & Dohme LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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