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Active Not RecruitingNCT05172271

Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

This study is active but not recruiting. It focuses on depression and currently lists study information in the United States.

DepressionDeviceFrom 25 Years to 64 Years
In plain English

Key information made simple

This study is comparing MagPro TMS Stimulator and coil with Sham TEST for people with depression, bipolarity, or Unipolar Major Depression. Participants receive MagPro TMS Stimulator and coil or Sham TEST and complete study visits and assessments. Some participants may receive Sham TEST instead of the study treatment, and direct benefit is not guaranteed.

What to expect

Your next step

The official record suggests a mix of remote and in-person participation through a clinic, with sites including National Institutes of Health Clinical Center in Bethesda. Participation appears to involve questionnaires, interviews, or regular check-ins about day-to-day experience. The main fit is usually matching the main diagnosis and being able to understand the study and consent. The official record does not list a formal phase, which usually means this is focused more on feasibility, delivery, or support than a standard drug-development stage.

Public study data

Key study information

Official title
A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)
Condition
Major Depressive Disorder; Bipolar Disorder; Unipolar Major Depression
Study status
Active Not Recruiting
Sponsor / lead affiliation
National Institute of Mental Health (NIMH)
Intervention
MagPro TMS Stimulator and coil, Thymatron(R) System IV, Magnetic Resonance Imaging Scanner, ECT device without stimulation
Location / country
United States
Registry
ClinicalTrials.gov
Why this study may matter

Why this study may matter

This study may matter because it is evaluating MagPro TMS Stimulator and coil, Thymatron(R) System IV, Magnetic Resonance Imaging Scanner, ECT device without stimulation in a structured research setting. For people exploring bipolarity research, clear information about the goal, status, contacts, and official source can support better questions before any decision.

Before joining

Questions to ask before joining

Official source

Registry reference

This page links back to the public source record so people can verify details directly with the registry and research team.

If you want the full study description, eligibility criteria, locations, and sponsor information in the original format, this is the place to check before taking the next step.

Open source record
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Ask HopeStage to review this study with me

This form records your interest so HopeStage can follow up with practical guidance. It is not a medical eligibility decision and it does not guarantee a study spot.

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In practice

For you

Taking part may give access to a new approach being evaluated.

It requires regular follow-up, often through questionnaires or interviews.

Mixes in-person and remote participation.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

Study clarity

Things to check before joining

Sponsor
National Institute of Mental Health (NIMH)
Sponsor type
Government agency
Main activity
brain stimulation
Intervention
MagPro TMS Stimulator and coil, Thymatron(R) System IV, Magnetic Resonance Imaging Scanner, ECT device without stimulation
Time commitment
multiple visits or assessments
Study phase
Not available
Enrollment
Not available
Recruitment status
Active Not Recruiting
Source
Official registry link
FAQ

Questions about this study

What is Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)?

This study is exploring brain stimulation for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. It includes a comparison with a sham comparison. Direct benefit is not guaranteed.

Who is behind this study, and what type of sponsor is it?

This study is sponsored by National Institute of Mental Health (NIMH), a government agency. The National Institute of Mental Health is a U.S. federal research agency focused on mental health research. The sponsor is based in the United States. Sponsor website: https://www.nimh.nih.gov. You can verify the sponsor and study responsibility in the official registry record.

What does participation involve, what phase is it, and what should I ask about safety?

This study may involve brain stimulation, study visits, and assessments. The time commitment is multiple visits or assessments. The study phase is not available in HopeStage data. Check the official source record to see whether a phase is listed. Enrollment is not available in HopeStage data. HopeStage cannot say whether a study is safe or right for you. Before joining, ask the research team about possible risks, time commitment, visits, side effects, compensation, safety monitoring, and whether participation may affect your current care.

Where can I verify the study details?

Use the official source record linked on this page to check the full study description, recruitment status, eligibility criteria, locations, sponsor information, phase, enrollment, contact details, and any listed risks or requirements.