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CompletedNCT05304767

Safety study of KarXT in schizophrenia

This study is completed in the United States, in Bulgaria, in Japan, .... It is testing KarXT for schizophrenia.

SchizophreniaDrugFrom 18 Years to 65 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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In plain English

Key information made simple

What is this study testing?

This study is testing whether Xanomeline and Trospium Chloride Capsules may be useful for adults experiencing schizophrenia.

What would participation involve?

Participants may receive Xanomeline and Trospium Chloride Capsules, attend study visits with the research team. The registry lists locations in Bulgaria, in Japan, and in Serbia.

Who is it mainly for?

This study appears to be mainly for adults with schizophrenia.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)

  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: March 7, 2022
Recruitment status
Completed
Enrollment listed in the registry
290
Sponsor
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, Bulgaria, Japan, ...
Age range
From 18 Years to 65 Years
Official registry ID
NCT05304767
Official title
An Open-label Extension Study to Assess the Long-term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

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Study ID: NCT05304767. We help you review the study, but cannot decide medical eligibility.

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Bulgaria · 20 sites
  • Local Institution - 306
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Local Institution - 309
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Local Institution - 302
    Kazanlak, Stara Zagora
    Site status: Not listed — confirm with the team
  • Local Institution - 318
    Cherven Bryag
    Site status: Not listed — confirm with the team
  • Local Institution - 311
    Dupnitsa
    Site status: Not listed — confirm with the team
  • Local Institution - 316
    Kardzhali
    Site status: Not listed — confirm with the team
  • Local Institution - 304
    Novi Iskar
    Site status: Not listed — confirm with the team
  • Local Institution - 301
    Pleven
    Site status: Not listed — confirm with the team
  • Local Institution - 315
    Pleven
    Site status: Not listed — confirm with the team
  • Local Institution - 314
    Plovdiv
    Site status: Not listed — confirm with the team
  • Local Institution - 321
    Plovdiv
    Site status: Not listed — confirm with the team
  • Local Institution - 313
    Razgrad
    Site status: Not listed — confirm with the team
  • Local Institution - 312
    Sliven
    Site status: Not listed — confirm with the team
  • Local Institution - 305
    Sofia
    Site status: Not listed — confirm with the team
  • Local Institution - 319
    Sofia
    Site status: Not listed — confirm with the team
  • Local Institution - 307
    Sofia
    Site status: Not listed — confirm with the team
  • Local Institution - 303
    Sofia
    Site status: Not listed — confirm with the team
  • Local Institution - 317
    Targovishte
    Site status: Not listed — confirm with the team
  • Local Institution - 308
    Varna
    Site status: Not listed — confirm with the team
  • Local Institution - 310
    Vratsa
    Site status: Not listed — confirm with the team
Japan · 7 sites
  • Local Institution - 250
    Toyoake-shi, Aichi-ken
    Site status: Not listed — confirm with the team
  • Local Institution - 255
    Fukuoka, Fukuoka
    Site status: Not listed — confirm with the team
  • Local Institution - 257
    Shirakawa-shi, Fukushima
    Site status: Not listed — confirm with the team
  • Local Institution - 254
    Karatsu-shi, Saga-ken
    Site status: Not listed — confirm with the team
  • Local Institution - 253
    Meguro-ku, Tokyo
    Site status: Not listed — confirm with the team
  • Sangenjaya Neurology- Psychosomatic Clinic
    Setagaya-ku, Tokyo
    Site status: Not listed — confirm with the team
  • Local Institution - 256
    Shinjuku-ku, Tokyo-To
    Site status: Not listed — confirm with the team
Serbia · 11 sites
  • Local Institution - 403
    Belgrade
    Site status: Not listed — confirm with the team
  • Local Institution - 402
    Belgrade
    Site status: Not listed — confirm with the team
  • Local Institution - 405
    Belgrade
    Site status: Not listed — confirm with the team
  • Local Institution - 411
    Gornja Toponica
    Site status: Not listed — confirm with the team
  • Local Institution - 414
    Kovin
    Site status: Not listed — confirm with the team
  • Local Institution - 404
    Kovin
    Site status: Not listed — confirm with the team
  • Local Institution - 401
    Kragujevac
    Site status: Not listed — confirm with the team
  • Local Institution - 406
    Kragujevac
    Site status: Not listed — confirm with the team
  • Local Institution - 407
    Kragujevac
    Site status: Not listed — confirm with the team
  • Local Institution - 408
    Kragujevac
    Site status: Not listed — confirm with the team
  • Local Institution - 410
    Novi Kneževac
    Site status: Not listed — confirm with the team
United States · 56 sites
  • Local Institution - 161
    Phoenix, Arizona
    Site status: Not listed — confirm with the team
  • Local Institution - 175
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Local Institution - 112
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Local Institution - 146
    Anaheim, California
    Site status: Not listed — confirm with the team
  • Local Institution - 130
    Bellflower, California
    Site status: Not listed — confirm with the team
  • Local Institution - 110
    Cerritos, California
    Site status: Not listed — confirm with the team
  • Local Institution - 167
    Culver City, California
    Site status: Not listed — confirm with the team
  • Local Institution - 127
    Garden Grove, California
    Site status: Not listed — confirm with the team
  • Local Institution - 152
    La Habra, California
    Site status: Not listed — confirm with the team
  • Local Institution - 126
    Lafayette, California
    Site status: Not listed — confirm with the team
  • Local Institution - 131
    Lemon Grove, California
    Site status: Not listed — confirm with the team
  • Local Institution - 181
    Oceanside, California
    Site status: Not listed — confirm with the team
  • Local Institution - 150
    Orange, California
    Site status: Not listed — confirm with the team
  • Local Institution - 170
    Pico Rivera, California
    Site status: Not listed — confirm with the team
  • Local Institution - 144
    Riverside, California
    Site status: Not listed — confirm with the team
  • Local Institution - 164
    Stanford, California
    Site status: Not listed — confirm with the team
  • Local Institution - 109
    Torrance, California
    Site status: Not listed — confirm with the team
  • Local Institution - 186
    Coral Gables, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 182
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 133
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 105
    Lauderhill, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 145
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 171
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 173
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 153
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 156
    Pembroke Pines, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 155
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Local Institution - 136
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Local Institution - 111
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Local Institution - 192
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Local Institution - 138
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Local Institution - 169
    Marietta, Georgia
    Site status: Not listed — confirm with the team
  • Local Institution - 151
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Local Institution - 166
    Gaithersburg, Maryland
    Site status: Not listed — confirm with the team
  • Local Institution - 187
    Boston, Massachusetts
    Site status: Not listed — confirm with the team
  • Local Institution - 129
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Local Institution - 178
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Local Institution - 174
    Omaha, Nebraska
    Site status: Not listed — confirm with the team
  • Local Institution - 148
    Las Vegas, Nevada
    Site status: Not listed — confirm with the team
  • Local Institution - 188
    Berlin, New Jersey
    Site status: Not listed — confirm with the team
  • Local Institution - 104
    New York, New York
    Site status: Not listed — confirm with the team
  • Local Institution - 160
    New York, New York
    Site status: Not listed — confirm with the team
  • Local Institution - 157
    New York, New York
    Site status: Not listed — confirm with the team
  • Local Institution - 108
    Rochester, New York
    Site status: Not listed — confirm with the team
  • Local Institution - 113
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • Local Institution - 176
    Hickory, North Carolina
    Site status: Not listed — confirm with the team
  • Local Institution - 163
    Independence, Ohio
    Site status: Not listed — confirm with the team
  • Local Institution - 179
    Eugene, Oregon
    Site status: Not listed — confirm with the team
  • Local Institution - 128
    Austin, Texas
    Site status: Not listed — confirm with the team
  • Local Institution - 190
    Fort Worth, Texas
    Site status: Not listed — confirm with the team
  • Local Institution - 180
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Local Institution - 103
    Irving, Texas
    Site status: Not listed — confirm with the team
  • Local Institution - 172
    Richardson, Texas
    Site status: Not listed — confirm with the team
  • Local Institution - 159
    Richmond, Texas
    Site status: Not listed — confirm with the team
  • Local Institution - 140
    Rutland, Vermont
    Site status: Not listed — confirm with the team
  • Local Institution - 101
    Bellevue, Washington
    Site status: Not listed — confirm with the team
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with schizophrenia. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Xanomeline and Trospium Chloride Capsules. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with schizophrenia; age range: From 18 Years to 65 Years. The criteria appear fairly specific, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Karuna Therapeutics, Inc., a Bristol Myers Squibb company, which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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