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TerminatedNCT05443724

Safety study of CVL-231 (Emraclidine) in schizophrenia

This study was terminated in the United States, in Bulgaria, in Hungary, .... It is testing CVL-231 (Emraclidine) for schizophrenia.

SchizophreniaDrugFrom 18 Years to 65 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

Check the official registry

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Bulgaria · 13 sites
  • Sofia, Sofia-Grad
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Sofia, Sofia-Grad
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Sofia, Sofia-Grad
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Sofia, Sofia-Grad
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Sofia, Sofia-Grad
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Sofia, Sofia-Grad
    Sofia, Sofia-Grad
    Site status: Not listed — confirm with the team
  • Pazardzhik, Pazardzhik
    Pazardzhik
    Site status: Not listed — confirm with the team
  • Pleven, Pleven
    Pleven
    Site status: Not listed — confirm with the team
  • Sliven, Sliven
    Sliven
    Site status: Not listed — confirm with the team
  • Stara Zagora, Stara Zagora
    Stara Zagora
    Site status: Not listed — confirm with the team
  • Varna, Varna
    Varna
    Site status: Not listed — confirm with the team
  • Veliko Tarnovo, Veliko Tarnovo
    Veliko Tarnovo
    Site status: Not listed — confirm with the team
  • Vratsa, Vratsa
    Vratsa
    Site status: Not listed — confirm with the team
Hungary · 2 sites
  • Kalocsa, Bács-Kiskun
    Kalocsa, Bács-Kiskun county
    Site status: Not listed — confirm with the team
  • Gyor, Gyor-Moson-Sopron
    Győr, Győr-Moson-Sopron
    Site status: Not listed — confirm with the team
Puerto Rico · 2 sites
  • San Juan, Puerto Rico
    San Juan
    Site status: Not listed — confirm with the team
  • San Juan, Puerto Rico
    San Juan
    Site status: Not listed — confirm with the team
Ukraine · 6 sites
  • Ivano Frankivsk, Ivano Frankivsk
    Ivano-Frankivsk, Ivano-Frankivsk Oblast
    Site status: Not listed — confirm with the team
  • Lviv, L'vivs'ka Oblast
    Lviv, Lviv Oblast
    Site status: Not listed — confirm with the team
  • Kropyvnytskyi, Kropyvnytskyi
    Kropyvnytskyi
    Site status: Not listed — confirm with the team
  • Kyiv, Kyïv
    Kyiv
    Site status: Not listed — confirm with the team
  • Smila, Smila
    Smila
    Site status: Not listed — confirm with the team
  • Vinnytsia, Vinnytsia
    Vinnytsia
    Site status: Not listed — confirm with the team
United States · 62 sites
  • Phoenix, Arizona
    Phoenix, Arizona
    Site status: Not listed — confirm with the team
  • Bryant, Arkansas
    Bryant, Arkansas
    Site status: Not listed — confirm with the team
  • Little Rock, Arkansas
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Anaheim, California
    Anaheim, California
    Site status: Not listed — confirm with the team
  • Bellflower, California
    Bellflower, California
    Site status: Not listed — confirm with the team
  • Culver City, California
    Culver City, California
    Site status: Not listed — confirm with the team
  • Garden Grove, California
    Garden Grove, California
    Site status: Not listed — confirm with the team
  • La Habra, California
    La Habra, California
    Site status: Not listed — confirm with the team
  • Lemon Grove, California
    Lemon Grove, California
    Site status: Not listed — confirm with the team
  • Montclair, California
    Montclair, California
    Site status: Not listed — confirm with the team
  • Orange,California
    Orange, California
    Site status: Not listed — confirm with the team
  • Pico Rivera, California
    Pico Rivera, California
    Site status: Not listed — confirm with the team
  • Riverside, California
    Riverside, California
    Site status: Not listed — confirm with the team
  • San Diego, California
    San Diego, California
    Site status: Not listed — confirm with the team
  • San Diego, California
    San Diego, California
    Site status: Not listed — confirm with the team
  • San Diego, California
    San Diego, California
    Site status: Not listed — confirm with the team
  • Sherman Oaks, California
    Sherman Oaks, California
    Site status: Not listed — confirm with the team
  • Torrance, California
    Torrance, California
    Site status: Not listed — confirm with the team
  • Walnut Creek, California
    Walnut Creek, California
    Site status: Not listed — confirm with the team
  • New Haven, Connecticut
    New Haven, Connecticut
    Site status: Not listed — confirm with the team
  • Bonita Springs,Florida
    Bonita Springs, Florida
    Site status: Not listed — confirm with the team
  • Fort Myers, Florida
    Fort Myers, Florida
    Site status: Not listed — confirm with the team
  • Hialeah, Florida
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Hialeah, Florida
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • Miami, Florida
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Miami, Florida
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Miami, Florida
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Miami Lakes, Florida
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Miami Lakes, Florida
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Miami Springs, Florida
    Miami Springs, Florida
    Site status: Not listed — confirm with the team
  • Oakland Park, Florida
    Oakland Park, Florida
    Site status: Not listed — confirm with the team
  • West Palm Beach, Florida
    West Palm Beach, Florida
    Site status: Not listed — confirm with the team
  • Atlanta, Georgia
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Atlanta, Georgia
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Atlanta, Georgia
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Decatur, Georgia
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Savannah,Georgia
    Savannah, Georgia
    Site status: Not listed — confirm with the team
  • Berwyn, Illinois
    Berwyn, Illinois
    Site status: Not listed — confirm with the team
  • Chicago, Illinois
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Chicago, Illinois
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Chicago, Illinois
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Chicago, Illinois
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Chicago, Illinois
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Marrero, Louisiana
    Marrero, Louisiana
    Site status: Not listed — confirm with the team
  • Shreveport, Louisiana
    Shreveport, Louisiana
    Site status: Not listed — confirm with the team
  • Gaithersburg, Maryland
    Gaithersburg, Maryland
    Site status: Not listed — confirm with the team
  • Flowood, Mississippi
    Flowood, Mississippi
    Site status: Not listed — confirm with the team
  • Las Vegas, Nevada
    Las Vegas, Nevada
    Site status: Not listed — confirm with the team
  • Berlin, New Jersey
    Berlin, New Jersey
    Site status: Not listed — confirm with the team
  • Cedarhurst, New York
    Cedarhurst, New York
    Site status: Not listed — confirm with the team
  • New York, New York
    New York, New York
    Site status: Not listed — confirm with the team
  • Staten Island, New York
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • Charlotte, North Carolina
    Charlotte, North Carolina
    Site status: Not listed — confirm with the team
  • North Canton, Ohio
    North Canton, Ohio
    Site status: Not listed — confirm with the team
  • Oklahoma City, Oklahoma
    Oklahoma City, Oklahoma
    Site status: Not listed — confirm with the team
  • Franklin,Tennessee
    Franklin, Tennessee
    Site status: Not listed — confirm with the team
  • Austin, Texas
    Austin, Texas
    Site status: Not listed — confirm with the team
  • DeSoto, Texas
    DeSoto, Texas
    Site status: Not listed — confirm with the team
  • Houston, Texas
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Houston, Texas
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Plano, Texas
    Plano, Texas
    Site status: Not listed — confirm with the team
  • Richardson, Texas
    Richardson, Texas
    Site status: Not listed — confirm with the team
In plain English

Key information made simple

What is this study testing?

This study is testing whether Emraclidine 30 mg may be useful for adults experiencing schizophrenia.

What would participation involve?

Participants may receive Emraclidine 30 mg, attend study visits with the research team. The registry lists locations in Bulgaria, in Hungary, and in the United States.

Who is it mainly for?

This study appears to be mainly for adults with schizophrenia.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

What to expect

Your next step

Study sites are listed in the registry. Recruitment status can differ between sites. Ask the research team to confirm the location, any in-person visits, time commitment, costs or compensation, and participation criteria.

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: September 1, 2022
Recruitment status
Terminated
Enrollment listed in the registry
698
Sponsor
AbbVie
Sponsor type
Unknown or unclear
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States, Bulgaria, Hungary, ...
Age range
From 18 Years to 65 Years
Official registry ID
NCT05443724
Official title
A 52-week, Phase 2, Open-label Trial to Evaluate the Long-term Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia
Official source
Official registry link

Want help reviewing this study?

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Study ID: NCT05443724. We help you review the study, but cannot decide medical eligibility.
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with schizophrenia. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Emraclidine 30 mg. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with schizophrenia; age range: From 18 Years to 65 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by AbbVie, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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