Key information made simple
This summary needs review. Please check the official study record and contact the research team for details.
CompletedNCT05455684
Safety study of Efficacy, Safety, and Tolerability of Aticaprant 10 mg in depression
This study is completed in the United States, in Australia, in Belgium, .... It is testing Efficacy, Safety, and Tolerability of Aticaprant 10 mg for depression.
Depression, AnhedoniaDrugFrom 18 Years to 74 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Then choose your country and confirm availability with each study site.
Check the study details
Check the official source, then confirm these points with the research team.
View official study record (opens in a new tab)
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
Study start dateStarted: June 22, 2022
- Recruitment status
- Completed
- Enrollment listed in the registry
- 513
- Sponsor
- Janssen Research & Development, LLC
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- Medication / drug, OTHER
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
- Locations
- United States, Australia, Belgium, ...
- Age range
- From 18 Years to 74 Years
- Official registry ID
- NCT05455684
- Official title
- A Randomized, Double-blind, Multicenter, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
View official study record (opens in a new tab)The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Argentina · 8 sites
- Hospital ItalianoBuenos AiresSite status: Not listed — confirm with the team
- STAT Research S ABuenos AiresSite status: Not listed — confirm with the team
- CIPRECBuenos AiresSite status: Not listed — confirm with the team
- CENydET - Centro Neurobiologico y de Stress TraumaticoCiudad Autonoma Buenos AiresSite status: Not listed — confirm with the team
- Fundacion LennoxCórdobaSite status: Not listed — confirm with the team
- CENPIALa PlataSite status: Not listed — confirm with the team
- ResolutionMendozaSite status: Not listed — confirm with the team
- Instituto Medico de La Fundacion Estudios ClinicosRosarioSite status: Not listed — confirm with the team
Australia · 3 sites
- Peninsula Therapeutic & Research GroupFrankstonSite status: Not listed — confirm with the team
- Albert Road ClinicMelbourneSite status: Not listed — confirm with the team
- The Alfred HospitalMelbourneSite status: Not listed — confirm with the team
Belgium · 4 sites
- AnimaAlkenSite status: Not listed — confirm with the team
- C.H.U. BrugmannBrusselsSite status: Not listed — confirm with the team
- Pz DuffelDuffelSite status: Not listed — confirm with the team
- VitazSint-NiklaasSite status: Not listed — confirm with the team
Brazil · 8 sites
- Universidade Federal do Ceara Hospital Universitario Walter CantidioFortalezaSite status: Not listed — confirm with the team
- Instituto Goiano de NeuropsiquiatriaGoiâniaSite status: Not listed — confirm with the team
- NPCRS Nucleo de Pesquisa Clinica do Rio Grande do SulPorto AlegreSite status: Not listed — confirm with the team
- Ruschel Medicina e Pesquisa Clínica LtdaRio de JaneiroSite status: Not listed — confirm with the team
- CEMEC - Centro Multidisciplinar de Estudos ClínicosSão Bernardo do CampoSite status: Not listed — confirm with the team
- Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de BaseSão José do Rio PretoSite status: Not listed — confirm with the team
- CPQuali Pesquisa Clinica LTDA MESão PauloSite status: Not listed — confirm with the team
- BR TrialsSão PauloSite status: Not listed — confirm with the team
Bulgaria · 6 sites
- Ambulatory for Individual Practice for Specialized Medical Care in Psychiatry Dr. Ivo Natsov ETCherven BryagSite status: Not listed — confirm with the team
- Ambulatory Group practice for specialized help in psychiary Philipopolis ODDPlovdivSite status: Not listed — confirm with the team
- Medical Center Mentalcare OODPlovdivSite status: Not listed — confirm with the team
- Mental Health Center - RousseRousseSite status: Not listed — confirm with the team
- Medical Center St. NaumSofiaSite status: Not listed — confirm with the team
- Mental Health Center - Veliko Tarnovo EOODVeliko TarnovoSite status: Not listed — confirm with the team
Czechia · 7 sites
- Narodni ustav dusevniho zdraviKlecanySite status: Not listed — confirm with the team
- A Shine S R OPilsenSite status: Not listed — confirm with the team
- Clintrial s r oPragueSite status: Not listed — confirm with the team
- AD71 s.r.o.PragueSite status: Not listed — confirm with the team
- Praglandia s r oPragueSite status: Not listed — confirm with the team
- NeuropsychiatrieHK, s.r.o.PragueSite status: Not listed — confirm with the team
- Psychiatricka ordinaceÚstí nad LabemSite status: Not listed — confirm with the team
Hungary · 7 sites
- Obudai Egeszsegugyi Centrum KftBudapestSite status: Not listed — confirm with the team
- Semmelweis EgyetemBudapestSite status: Not listed — confirm with the team
- Nyiro Gyula KorhazBudapestSite status: Not listed — confirm with the team
- Bugat Pal KorhazGyöngyösSite status: Not listed — confirm with the team
- Dr Mathe es Tarsa BtKalocsaSite status: Not listed — confirm with the team
- PsychoTech KftPécsSite status: Not listed — confirm with the team
- Tolna Megyei Balassa Janos KorhazSzekszárdSite status: Not listed — confirm with the team
Italy · 7 sites
- Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII)BergamoSite status: Not listed — confirm with the team
- Azienda Ospedaliero Universitaria Mater DominiCatanzaroSite status: Not listed — confirm with the team
- AUSL LE di LecceLecceSite status: Not listed — confirm with the team
- Fondazione IRCCS Ca Granda Ospedale Maggiore PoliclinicoMilanSite status: Not listed — confirm with the team
- ASST Fatebenefratelli SaccoMilanSite status: Not listed — confirm with the team
- Ospedale San RaffaeleMilanSite status: Not listed — confirm with the team
- Azienda Ospedaliera Universitaria Senese Policlinico Santa Maria alle ScotteSienaSite status: Not listed — confirm with the team
Poland · 7 sites
- Gabinet Lekarski Psychiatryczny Ireneusz KaczorowskiBełchatówSite status: Not listed — confirm with the team
- Mlynowamed Specjalistyczny Psychiatryczny Gabinet Lekarski Joanna LazarczykBialystokSite status: Not listed — confirm with the team
- Centrum Badan Klinicznych PI House sp z o oGdanskSite status: Not listed — confirm with the team
- Specjalistyczna Indywidualna Praktyka LekarskaLodzSite status: Not listed — confirm with the team
- SPZOZ Uniwersytecki Szpi.Klin. nr 4 UM w LodziLodzSite status: Not listed — confirm with the team
- Osrodek Badan Klinicznych CROMEDPoznanSite status: Not listed — confirm with the team
- Specjalistyczny Gabinet Psychiatryczny Kowalkowski GerardTorunSite status: Not listed — confirm with the team
Portugal · 3 sites
- Hospital de BragaBragaSite status: Not listed — confirm with the team
- Hospital CUF Inf. SantoLisbonSite status: Not listed — confirm with the team
- Fund. ChampalimaudLisbonSite status: Not listed — confirm with the team
Spain · 10 sites
- Institucion Hosp Hestia PalauBarcelonaSite status: Not listed — confirm with the team
- Hosp Univ Vall D HebronBarcelonaSite status: Not listed — confirm with the team
- Hosp Clinic de BarcelonaBarcelonaSite status: Not listed — confirm with the team
- Hosp. Univ. La PazMadridSite status: Not listed — confirm with the team
- Hosp Regional Univ de MalagaMálagaSite status: Not listed — confirm with the team
- Hosp. Univ. Son EspasesPalma de MallorcaSite status: Not listed — confirm with the team
- Hosp. El BierzoPonferradaSite status: Not listed — confirm with the team
- Corporacio Sanitari Parc TauliSabadellSite status: Not listed — confirm with the team
- Hosp. Alvaro CunqueiroVigoSite status: Not listed — confirm with the team
- Hosp. Psiquiatrico AlavaVitoria-GasteizSite status: Not listed — confirm with the team
Sweden · 4 sites
- Sahlgrenska UniversitetssjukhusetGothenburgSite status: Not listed — confirm with the team
- ProbarE i Lund ABLundSite status: Not listed — confirm with the team
- ProbarE i Stockholm ABStockholmSite status: Not listed — confirm with the team
- Studieenheten Akademiskt Specialistcentrum StockholmStockholmSite status: Not listed — confirm with the team
United States · 46 sites
- SW Biomedical Research LLCTucson, ArizonaSite status: Not listed — confirm with the team
- University of ArizonaTucson, ArizonaSite status: Not listed — confirm with the team
- Advanced Research Center IncAnaheim, CaliforniaSite status: Not listed — confirm with the team
- Proscience Research GroupCulver City, CaliforniaSite status: Not listed — confirm with the team
- Behavioral Research Specialists LLCGlendale, CaliforniaSite status: Not listed — confirm with the team
- Asclepes ResearchLong Beach, CaliforniaSite status: Not listed — confirm with the team
- Excell Research IncOceanside, CaliforniaSite status: Not listed — confirm with the team
- Syrentis Clinical ResearchSanta Ana, CaliforniaSite status: Not listed — confirm with the team
- Viking Clinical Research LtdTemecula, CaliforniaSite status: Not listed — confirm with the team
- University of Connecticut Health CenterFarmington, ConnecticutSite status: Not listed — confirm with the team
- Innovative Research of West Florida, IncorporatedClearwater, FloridaSite status: Not listed — confirm with the team
- Vertex Research Group, IncClermont, FloridaSite status: Not listed — confirm with the team
- Gulfcoast Medical Research CenterFort Myers, FloridaSite status: Not listed — confirm with the team
- New Life Medical Research Center, Inc.Hialeah, FloridaSite status: Not listed — confirm with the team
- Amedica Research Institute IncHialeah, FloridaSite status: Not listed — confirm with the team
- Convenient Medical CenterHialeah, FloridaSite status: Not listed — confirm with the team
- Galiz ResearchHialeah, FloridaSite status: Not listed — confirm with the team
- Pharmax Research Clinic IncMiami, FloridaSite status: Not listed — confirm with the team
- A Plus ResearchMiami, FloridaSite status: Not listed — confirm with the team
- Meridian International ResearchMiami Gardens, FloridaSite status: Not listed — confirm with the team
- University of MiamiMiami Lakes, FloridaSite status: Not listed — confirm with the team
- Medical Research Group of Central FloridaOrange City, FloridaSite status: Not listed — confirm with the team
- USF, Department of Psychiatry and Behavioral NeurosciencesTampa, FloridaSite status: Not listed — confirm with the team
- Research Network AmericaBerwyn, IllinoisSite status: Not listed — confirm with the team
- Chicago Research CenterChicago, IllinoisSite status: Not listed — confirm with the team
- University of Kansas Medical Center Research InstituteKansas City, KansasSite status: Not listed — confirm with the team
- Clinical Trials of AmericaMonroe, LouisianaSite status: Not listed — confirm with the team
- ActivMed Practices and ResearchMethuen, MassachusettsSite status: Not listed — confirm with the team
- Psychiatric Care and Research Center (PCRC)O'Fallon, MissouriSite status: Not listed — confirm with the team
- Bioscience Research LLCMount Kisco, New YorkSite status: Not listed — confirm with the team
- Fieve Clinical Research IncNew York, New YorkSite status: Not listed — confirm with the team
- Finger Lakes Clinical ResearchRochester, New YorkSite status: Not listed — confirm with the team
- Montefiore Medical Center PRIMEThe Bronx, New YorkSite status: Not listed — confirm with the team
- Patient Priority Clinical Sites LLCCincinnati, OhioSite status: Not listed — confirm with the team
- University of Cincinnati Medical CenterCincinnati, OhioSite status: Not listed — confirm with the team
- Midwest Clinical Research CenterDayton, OhioSite status: Not listed — confirm with the team
- Charak Center for Health and WellnessGarfield Heights, OhioSite status: Not listed — confirm with the team
- Suburban Research AssociatesMedia, PennsylvaniaSite status: Not listed — confirm with the team
- University of Pennsylvania - Perelman School of MedicinePhiladelphia, PennsylvaniaSite status: Not listed — confirm with the team
- West Houston Clinical Research ServiceBellaire, TexasSite status: Not listed — confirm with the team
- North Texas Clinical TrialsFort Worth, TexasSite status: Not listed — confirm with the team
- Bay Area Clinical ServicesFriendswood, TexasSite status: Not listed — confirm with the team
- Clinical Trial Network - HoustonHouston, TexasSite status: Not listed — confirm with the team
- Alpine Research OrganizationClinton, UtahSite status: Not listed — confirm with the team
- University of VirginiaCharlottesville, VirginiaSite status: Not listed — confirm with the team
- Northwest Clinical Research CenterBellevue, WashingtonSite status: Not listed — confirm with the team
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT05455684. We help you review the study, but cannot decide medical eligibility.
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving Aticaprant, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 74 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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