RecruitingNCT05511909
Buspirone, lofexidine, or placebo during opioid withdrawal
About this title
Read the official source — NCT05511909Medication studyAges 18–75United StatesAddiction
Understand this study
Who could participate?
Listed age limits: 18 years to 75 years.
What will I do during this study?
Participants stay in a residential research unit for about 10 to 12 days. They are randomly assigned to buspirone, lofexidine or placebo (an inactive comparison treatment) alongside a supervised opioid taper, followed by observation after the taper.
- Listed locations
- BaltimoreSee all locations and recruitment
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Participation duration
- A residential study lasting about 10 to 12 days
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: December 15, 2022
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 100
- Sponsor
- University of Maryland, Baltimore
- Sponsor type
- University
- Study type
- Drug
- Intervention type
- Medication / drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- From 18 Years to 75 Years
- Official registry ID
- NCT05511909
- Official title
Show the full official title
Evaluating a Mechanistically-Supported Pharmacotherapy to Treat Opioid Withdrawal
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Baltimore
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is University of Maryland, Baltimore, a university.
Does this study involve medication?
Yes. The study involves medication, including Buspirone, Lofexidine and Placebo.
Who can participate?
Listed age limits: 18 years to 75 years.
Is this study still recruiting?
The registry lists this study as recruiting.
