Key information made simple
This summary needs review. Please check the official study record and contact the research team for details.
CompletedNCT05550532
Safety study of Efficacy, Safety, and Tolerability of Aticaprant 10 mg in depression
This study is completed in the United States, in France, in Canada, .... It is testing Efficacy, Safety, and Tolerability of Aticaprant 10 mg for depression.
Depression, AnhedoniaDrugFrom 18 Years to 74 Years
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
Then choose your country and confirm availability with each study site.
Check the study details
Check the official source, then confirm these points with the research team.
View official study record (opens in a new tab)
Questions to ask before joining
- What are the exact eligibility criteria, and what could exclude someone?
- How many visits, assessments, or follow-ups are expected, and over what period?
- What risks, side effects, practical burdens, or alternatives should be understood first?
- Who should be contacted to confirm locations, timing, compensation, and next steps?
Things to check before joining
Study start dateStarted: December 6, 2022
- Recruitment status
- Completed
- Enrollment listed in the registry
- 444
- Sponsor
- Janssen Research & Development, LLC
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- Medication / drug, OTHER
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
- Locations
- United States, France, Canada, ...
- Age range
- From 18 Years to 74 Years
- Official registry ID
- NCT05550532
- Official title
- A Randomized, Double-blind, Multicenter, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy
Check recruitment and locations
Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.
View official study record (opens in a new tab)The overall study status can differ from each site's status. Open a country to see its locations and their registry status.
Argentina · 9 sites
- Fundacion para el Estudio y Tratamiento de las Enfermedades MentalesBuenos AiresSite status: Not listed — confirm with the team
- CEN Consultorios Especializados en NeurocienciasCórdobaSite status: Not listed — confirm with the team
- Instituto Medico DAMICCórdobaSite status: Not listed — confirm with the team
- Centro Medico LuquezCórdobaSite status: Not listed — confirm with the team
- INSA Instituto de Neurociencias San AgustínLa PlataSite status: Not listed — confirm with the team
- Clinica Privada de Salud Mental Santa Teresa de ÁvilaLa PlataSite status: Not listed — confirm with the team
- C I A P Centro de investigacion y Asistencia en PsiquiatriaRosarioSite status: Not listed — confirm with the team
- Clinica Mayo de UMCBSan Miguel de TucumánSite status: Not listed — confirm with the team
- Clinica El JardinSantiago del EsteroSite status: Not listed — confirm with the team
Brazil · 2 sites
- Trial Tech Tecnologia em Pesquisas com MedicamentosCuritibaSite status: Not listed — confirm with the team
- Associacao Hospitalar Moinhos de VentoPorto AlegreSite status: Not listed — confirm with the team
Bulgaria · 5 sites
- MHC - Sofia, EOODSofiaSite status: Not listed — confirm with the team
- DCC 'Sv. Vrach and Sv. Sv. Kuzma and Damyan', OODSofiaSite status: Not listed — confirm with the team
- Medical Center Hera EOODSofiaSite status: Not listed — confirm with the team
- Medical Center Intermedica, OODSofiaSite status: Not listed — confirm with the team
- Diagnostic Consulting Center Mladost - M VarnaVarnaSite status: Not listed — confirm with the team
Canada · 2 sites
- Alpha Recherche CliniqueQuébec, QuebecSite status: Not listed — confirm with the team
- DIEX Recherche Sherbrooke IncSherbrooke, QuebecSite status: Not listed — confirm with the team
China · 17 sites
- Hebei Mental Health CenterBaodingSite status: Not listed — confirm with the team
- Beijing Anding Hospital of Capital Medical UniversityBeijingSite status: Not listed — confirm with the team
- Beijing Huilongguan HospitalBeijingSite status: Not listed — confirm with the team
- Peking University Sixth HospitalBeijingSite status: Not listed — confirm with the team
- The second Xiangya Hospital of Central South UniversityChangshaSite status: Not listed — confirm with the team
- West China Hospital Sichuan UniversityChengduSite status: Not listed — confirm with the team
- Guangdong Provincial People's HospitalGuangzhouSite status: Not listed — confirm with the team
- Huzhou third people's HospitalHuzhouSite status: Not listed — confirm with the team
- Shanghai Mental Health CenterShanghaiSite status: Not listed — confirm with the team
- Tongji Hospital of Tongji UniversityShanghaiSite status: Not listed — confirm with the team
- The First Hospital of Hebei Medical UniversityShijiazhuangSite status: Not listed — confirm with the team
- Suzhou Guangji HospitalSuzhouSite status: Not listed — confirm with the team
- Tianjin Anding HospitalTianjinSite status: Not listed — confirm with the team
- Wuhan Mental Health CenterWuhanSite status: Not listed — confirm with the team
- Wuhu Hospital of Beijing Anding hospitalWuhuSite status: Not listed — confirm with the team
- XiAn Mental Healthcare CenterXi'anSite status: Not listed — confirm with the team
- The First Affiliated Hospital of Zhengzhou UniversityZhengzhouSite status: Not listed — confirm with the team
Czechia · 4 sites
- Psychiatricka ambulance, MUDr. Marta HolanovaBrnoSite status: Not listed — confirm with the team
- Neuroterapie KH S R OKutná HoraSite status: Not listed — confirm with the team
- Medical Services Prague S R OPragueSite status: Not listed — confirm with the team
- Institut Neuropsychiatricke pecePragueSite status: Not listed — confirm with the team
France · 6 sites
- CHU de Brest - Hopital de la Cavale BlancheBoharsSite status: Not listed — confirm with the team
- CHU Clermont-Ferrand - Hopital Gabriel MontpiedClermont-FerrandSite status: Not listed — confirm with the team
- Cabinet Medical des Drs Prizac-Desbonnet ScottezDouaiSite status: Not listed — confirm with the team
- CHU de Nantes hotel DieuNantesSite status: Not listed — confirm with the team
- Hopital Sainte AnneParisSite status: Not listed — confirm with the team
- CHRU de Tours Clinique Psychiatrique UniversitaireToursSite status: Not listed — confirm with the team
Poland · 4 sites
- Clinsante Osrodek Badan KlinicznychBydgoszczSite status: Not listed — confirm with the team
- Centrum Medyczne Care Clinic KatowiceKatowiceSite status: Not listed — confirm with the team
- Filip Rybakowski Specjalistyczna Praktyka LekarskaPoznanSite status: Not listed — confirm with the team
- Indywidualna Specjalistyczna Praktyka Lekarska Agnieszka Remlinger MolendaSuchy LasSite status: Not listed — confirm with the team
Slovakia · 8 sites
- Psychomed-Svatosavsky, s.r.o.Banská BystricaSite status: Not listed — confirm with the team
- Nemocnica s poliklinikou Prievidza so sidlom v BojniciachBojniceSite status: Not listed — confirm with the team
- Psychiatricka Ambulancia Mentum S.R.O.BratislavaSite status: Not listed — confirm with the team
- Epamed sroKošiceSite status: Not listed — confirm with the team
- Univerzitna nemocnica L. Pasteura KosiceKošiceSite status: Not listed — confirm with the team
- Liptovska Nemocnica S Poliklinikou Mudr. Ivana StodoluLiptovský MikulášSite status: Not listed — confirm with the team
- Psychiatricka Ambulancia Psycholine S.R.O.Rimavská SobotaSite status: Not listed — confirm with the team
- Crystal Comfort s.r.o.Vranov nad TopľouSite status: Not listed — confirm with the team
South Africa · 3 sites
- Cape Town Clinical Research CentreCape TownSite status: Not listed — confirm with the team
- Gert Bosch Pretoria South AfricaPretoriaSite status: Not listed — confirm with the team
- Somerset West Clinical Research UnitStrandSite status: Not listed — confirm with the team
South Korea · 10 sites
- Bucheon St. Mary's HospitalBucheon-siSite status: Not listed — confirm with the team
- Inje University Haeundae Paik HospitalBusanSite status: Not listed — confirm with the team
- CHA University ilsan Medical CenterGoyangSite status: Not listed — confirm with the team
- Korea University Ansan HospitalGyeonggi-doSite status: Not listed — confirm with the team
- KyungHee University HospitalSeoulSite status: Not listed — confirm with the team
- Korea University Anam HospitalSeoulSite status: Not listed — confirm with the team
- Asan Medical CenterSeoulSite status: Not listed — confirm with the team
- Samsung Medical CenterSeoulSite status: Not listed — confirm with the team
- The Catholic University of Korea Yeouido St. Mary's HospitalSeoulSite status: Not listed — confirm with the team
- Seoul National University HospitalSeoulSite status: Not listed — confirm with the team
Taiwan · 4 sites
- China Medical University HospitalTaichungSite status: Not listed — confirm with the team
- Taipei Medical UniversityTaipeiSite status: Not listed — confirm with the team
- Taipei Veterans General HospitalTaipeiSite status: Not listed — confirm with the team
- Cheng Hsin General HospitalTaipeiSite status: Not listed — confirm with the team
United Kingdom · 6 sites
- University of SussexBrightonSite status: Not listed — confirm with the team
- Royal Edinburgh HospitalEdinburghSite status: Not listed — confirm with the team
- Institute of PsychiatryLondonSite status: Not listed — confirm with the team
- Renfrewshire CMHTPaisleySite status: Not listed — confirm with the team
- Moorgreen HospitalSouthamptonSite status: Not listed — confirm with the team
- Crisis Resolution and Home Treatment TeamWigan and LeighSite status: Not listed — confirm with the team
United States · 51 sites
- University of Alabama at BirminghamBirmingham, AlabamaSite status: Not listed — confirm with the team
- Sunwise Clinical ResearchLafayette, CaliforniaSite status: Not listed — confirm with the team
- Pacific Neuropsychiatric SpecialistsOrange, CaliforniaSite status: Not listed — confirm with the team
- Prospective Research Innovations IncRancho Cucamonga, CaliforniaSite status: Not listed — confirm with the team
- University of California San Diego Medical CenterSan Diego, CaliforniaSite status: Not listed — confirm with the team
- CMB Clinical TrialsSantee, CaliforniaSite status: Not listed — confirm with the team
- California Neuroscience ResearchSherman Oaks, CaliforniaSite status: Not listed — confirm with the team
- Pacific Clinical Research Medical GroupUpland, CaliforniaSite status: Not listed — confirm with the team
- Next Level Clinical Trials, LLCWest Covina, CaliforniaSite status: Not listed — confirm with the team
- MCB Clinical Research Centers LLCColorado Springs, ColoradoSite status: Not listed — confirm with the team
- CNS Clinical Research GroupCoral Springs, FloridaSite status: Not listed — confirm with the team
- Sarkis Clinical TrialsGainesville, FloridaSite status: Not listed — confirm with the team
- New Life Medical Research Center, Inc.Hialeah, FloridaSite status: Not listed — confirm with the team
- K2 Medical ResearchMaitland, FloridaSite status: Not listed — confirm with the team
- Vital Care ResearchMiami, FloridaSite status: Not listed — confirm with the team
- Global Medical InstitutesMiami, FloridaSite status: Not listed — confirm with the team
- LCC Medical Research Institute IncMiami, FloridaSite status: Not listed — confirm with the team
- Florida Research Center Inc.Miami, FloridaSite status: Not listed — confirm with the team
- Ezy Medical ResearchMiami, FloridaSite status: Not listed — confirm with the team
- Felicidad Medical ResearchMiami, FloridaSite status: Not listed — confirm with the team
- Bravo Health Care CenterNorth Bay Village, FloridaSite status: Not listed — confirm with the team
- APG Research LLCOrlando, FloridaSite status: Not listed — confirm with the team
- Combined Research OrlandoOrlando, FloridaSite status: Not listed — confirm with the team
- Quantum LaboratoriesPompano Beach, FloridaSite status: Not listed — confirm with the team
- CDC Research Institute LLCPort Saint Lucie, FloridaSite status: Not listed — confirm with the team
- Psychiatric Medicine AssociatesSkokie, IllinoisSite status: Not listed — confirm with the team
- Tandem Clinical ResearchMarrero, LouisianaSite status: Not listed — confirm with the team
- CBH HealthGaithersburg, MarylandSite status: Not listed — confirm with the team
- Michigan Clinical Research InstituteAnn Arbor, MichiganSite status: Not listed — confirm with the team
- Revive Research InstituteFarmington Hills, MichiganSite status: Not listed — confirm with the team
- Midwest Research GroupSaint Charles, MissouriSite status: Not listed — confirm with the team
- Premier Psychiatric Research Institute, LLCLincoln, NebraskaSite status: Not listed — confirm with the team
- Erie County Medical CenterBuffalo, New YorkSite status: Not listed — confirm with the team
- Manhattan Behavioral MedicineNew York, New YorkSite status: Not listed — confirm with the team
- New Hope Clinical ResearchCharlotte, North CarolinaSite status: Not listed — confirm with the team
- Monroe Biomedical ResearchMonroe, North CarolinaSite status: Not listed — confirm with the team
- The Cleveland Clinic FoundationCleveland, OhioSite status: Not listed — confirm with the team
- Wexner Medical Center at the Ohio State UniversityColumbus, OhioSite status: Not listed — confirm with the team
- Conrad Clinical ResearchEdmond, OklahomaSite status: Not listed — confirm with the team
- Sooner Clinical ResearchOklahoma City, OklahomaSite status: Not listed — confirm with the team
- Paradigm Research Professionals, LLCOklahoma City, OklahomaSite status: Not listed — confirm with the team
- Lehigh Center for Clinical Research LLCAllentown, PennsylvaniaSite status: Not listed — confirm with the team
- Global Medical InstitutesMoosic, PennsylvaniaSite status: Not listed — confirm with the team
- Clinical Trials of South CarolinaCharleston, South CarolinaSite status: Not listed — confirm with the team
- Donald J Garcia Jr MD PAAustin, TexasSite status: Not listed — confirm with the team
- Relaro Medical TrialsDallas, TexasSite status: Not listed — confirm with the team
- UT Southwestern Medical CenterDallas, TexasSite status: Not listed — confirm with the team
- R and H Clinical ResearchStafford, TexasSite status: Not listed — confirm with the team
- Cedar PsychiatryMurray, UtahSite status: Not listed — confirm with the team
- Northwest Clinical Research CenterBellevue, WashingtonSite status: Not listed — confirm with the team
- Core Clinical ResearchEverett, WashingtonSite status: Not listed — confirm with the team
Ask HopeStage to help me review this study
This record does not confirm open recruitment. We can help you understand it and explore other studies.
Study ID: NCT05550532. We help you review the study, but cannot decide medical eligibility.
For you
Participation may contribute to research. Personal benefit is not guaranteed.
Ask the research team to explain the activities, time commitment, and follow-up involved.
Study sites are listed. Confirm the relevant site and any travel before making plans.
Not medical advice
Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com
Questions about this study
What is this study trying to understand?
This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.
Does this study involve a medication?
This appears to be a medication / drug study involving Aticaprant, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.
Who might this study be for?
This study may concern people with depression; age range: From 18 Years to 74 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.
What would I likely need to do?
You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.
What side effects, interactions, or treatment changes should I check?
If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.
Will I need to travel or attend in-person visits?
The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.
Who is behind this study?
This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.
Can I still join this study?
The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.
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