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CompletedNCT05624268

Psilocybin for treatment-resistant depression

This study is completed in the United States. It is testing psilocybin for treatment-resistant depression.

DepressionDrugOver 18 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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In plain English

Key information made simple

What is this study testing?

This study is testing whether Psilocybin may be useful for adults experiencing depression.

What would participation involve?

Participants may receive Psilocybin, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)

  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: January 24, 2023
Recruitment status
Completed
Enrollment listed in the registry
258
Sponsor
COMPASS Pathways
Sponsor type
Unknown or unclear
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States
Age range
Over 18 Years
Official registry ID
NCT05624268
Official title
A Phase III, Multicentre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Treatment-resistant Depression

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 40 sites
  • University of Arizona College of Medicine - Tuscon
    Tuscon, Arizona
    Site status: Not listed — confirm with the team
  • ProScience Research Group
    Culver City, California
    Site status: Not listed — confirm with the team
  • Collaborative Neuroscience Network, LLC
    Garden Grove, California
    Site status: Not listed — confirm with the team
  • Kadima Neuropsychiatry Institute
    La Jolla, California
    Site status: Not listed — confirm with the team
  • University California San Diego
    La Jolla, California
    Site status: Not listed — confirm with the team
  • California Center for Psychedelic Therapy
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • CalNeuro Research Group, Inc
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • Clarity Clinical Research, LLC
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • ATP Clinical Research, Inc.
    Orange, California
    Site status: Not listed — confirm with the team
  • Artemis Institute for Clinical Research
    San Diego, California
    Site status: Not listed — confirm with the team
  • Lumos Clinical Research Center
    San Jose, California
    Site status: Not listed — confirm with the team
  • Stanford University
    Stanford, California
    Site status: Not listed — confirm with the team
  • ASCLEPES Research Centers
    Thousand Oaks, California
    Site status: Not listed — confirm with the team
  • Comprehensive Psychiatric Care
    Norwich, Connecticut
    Site status: Not listed — confirm with the team
  • Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • APG Research, LLC
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • DMI Health Care Group, Inc
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Meridien Research/Accel Research
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Psych Atlanta
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Emory University
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Uptown Research Institute, LLC
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Sheppard Pratt Health System
    Baltimore, Maryland
    Site status: Not listed — confirm with the team
  • CBH Health, LLC
    Gaithersburg, Maryland
    Site status: Not listed — confirm with the team
  • Pharmasite Research, Inc
    Pikesville, Maryland
    Site status: Not listed — confirm with the team
  • University of Massachusetts Medical School
    North Worcester, Massachusetts
    Site status: Not listed — confirm with the team
  • University of Minnesota
    Minneapolis, Minnesota
    Site status: Not listed — confirm with the team
  • University of Missouri
    Columbia, Missouri
    Site status: Not listed — confirm with the team
  • Midwest Research Group
    Saint Charles, Missouri
    Site status: Not listed — confirm with the team
  • Washington University School of Medicine
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Alivation Research, LLC.
    Lincoln, Nebraska
    Site status: Not listed — confirm with the team
  • Bio Behavioral Health
    Toms River, New Jersey
    Site status: Not listed — confirm with the team
  • New York State Psychiatric Institute
    New York, New York
    Site status: Not listed — confirm with the team
  • The Medical Research Network, LLC
    New York, New York
    Site status: Not listed — confirm with the team
  • Insight Clinical Trials, LLC
    Beachwood, Ohio
    Site status: Not listed — confirm with the team
  • Neuro-Behaviroral Clinical Research, Inc.
    North Canton, Ohio
    Site status: Not listed — confirm with the team
  • Rivus Wellness & Research Institute
    Oklahoma City, Oklahoma
    Site status: Not listed — confirm with the team
  • Global Medical Institutes, LLC, Scranton Medical Institute
    Moosic, Pennsylvania
    Site status: Not listed — confirm with the team
  • UT Health Science Center at Houston (UTHSC-H)
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Cedar Clinical Research
    Draper, Utah
    Site status: Not listed — confirm with the team
  • Core Clinical Research
    Everett, Washington
    Site status: Not listed — confirm with the team

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Study ID: NCT05624268. We help you review the study, but cannot decide medical eligibility.
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Psilocybin. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: Over 18 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by COMPASS Pathways, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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