For research teamsHelp me find a study
Back to all studies
Active Not RecruitingNCT05711940

Psilocybin for treatment-resistant depression

This study is active but not recruiting in the United States, in France, in Canada, .... It is testing psilocybin for treatment-resistant depression.

DepressionDrugOver 18 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

Explore recruiting studies on this topic

Then choose your country and confirm availability with each study site.

In plain English

Key information made simple

What is this study testing?

This study is testing whether Psilocybin may be useful for adults experiencing depression.

What would participation involve?

Participants may receive Psilocybin, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Canada, in Czechia, and in Denmark.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)

  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: February 14, 2023
Recruitment status
Active Not Recruiting
Enrollment listed in the registry
572
Sponsor
COMPASS Pathways
Sponsor type
Unknown or unclear
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, France, Canada, ...
Age range
Over 18 Years
Official registry ID
NCT05711940
Official title
A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant Depression

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Canada · 9 sites
  • Diex Recherche Sherbrooke Inc.
    Québec, B.C.
    Site status: Not listed — confirm with the team
  • Medical Arts Health Research Centre, Kamloops
    Kamloops, British Columbia
    Site status: Not listed — confirm with the team
  • Okanagan Clinical Trials
    Kelowna, British Columbia
    Site status: Not listed — confirm with the team
  • Medical Arts Research Group - Penticton
    Penticton, British Columbia
    Site status: Not listed — confirm with the team
  • Chatham-Kent Clnical Trials Centre
    Chatham, Ontario
    Site status: Not listed — confirm with the team
  • St. Michael's Hospital
    Toronto, Ontario
    Site status: Not listed — confirm with the team
  • Centre for Addiction and Mental Health (CAMH)
    Toronto, Ontario
    Site status: Not listed — confirm with the team
  • Centre for Neurology Studies
    Vancouver
    Site status: Not listed — confirm with the team
  • Medical Arts Research Group
    Vancouver
    Site status: Not listed — confirm with the team
Czechia · 6 sites
  • National Institute of Mental Health
    Klecany
    Site status: Not listed — confirm with the team
  • Neuroterapie KH Sro
    Kutná Hora
    Site status: Not listed — confirm with the team
  • Psychiatric Ambulance
    Ostrava
    Site status: Not listed — confirm with the team
  • A-Shine s.r.o.
    Pilsen
    Site status: Not listed — confirm with the team
  • Psychedelicka klinika, s.r.o.
    Prague
    Site status: Not listed — confirm with the team
  • Institut Neuropsychiatricke Pece
    Prague
    Site status: Not listed — confirm with the team
Denmark · 1 site
  • Aalborg Universitetshospital-Psykiatrien Region Nordjylland
    Aalborg
    Site status: Not listed — confirm with the team
France · 4 sites
  • Ghu-Centre Hospitalier Sainte Anne, Centre de Recherche Clinique
    Paris, Paris
    Site status: Not listed — confirm with the team
  • Centre Hospitalier Universitaire de Nimes (CHU) - Hopital Universitaire Caremeau
    Nîmes
    Site status: Not listed — confirm with the team
  • Universite Paris VI Pierre et Marie Curie - Hopital de La Salpetriere - Centre Emotion - USR 3246 (CNRS UMR 7593)
    Paris
    Site status: Not listed — confirm with the team
  • Centre Hospitalier Sainte Anne - Clinique des Maladies Mentales et de l'Encephale (CMME)
    Paris
    Site status: Not listed — confirm with the team
Germany · 3 sites
  • Charite-Universitaetsmedizin Berlin
    Berlin
    Site status: Not listed — confirm with the team
  • Johann Wolfgang Goethe-Universitaet Frankfurt am Main - Klinik fuer Psychiatrie, Psychosomatik und Psychotherapie
    Frankfurt
    Site status: Not listed — confirm with the team
  • ZiP Campus Luebeck
    Lübeck
    Site status: Not listed — confirm with the team
Ireland · 2 sites
  • Tallaght University Hospital
    Dublin
    Site status: Not listed — confirm with the team
  • La Nua Day Hospital Mental Health Centre
    Galway
    Site status: Not listed — confirm with the team
Netherlands · 3 sites
  • University Medical Center Groningen
    Groningen
    Site status: Not listed — confirm with the team
  • Leids Universitair Medisch Centrum (LUMC) (Leiden University Medical Center) - Leiden Institute for Brain and Cognition (LIBC)
    Leiden
    Site status: Not listed — confirm with the team
  • Universitair Medisch Centrum Utrecht (UMC Utrecht)
    Utrecht
    Site status: Not listed — confirm with the team
Poland · 3 sites
  • Promente - Ośrodek Badań Klinicznych
    Bydgoszcz
    Site status: Not listed — confirm with the team
  • Uniwersyteckle Centrum Kliniczne, Klinika Psychiatrii Doroslych
    Gdansk
    Site status: Not listed — confirm with the team
  • Centrum Badan Klinicznych PI-House Sp. z o.o.
    Gdansk
    Site status: Not listed — confirm with the team
Spain · 6 sites
  • Hospital Clinic de Barcelona
    Barcelona
    Site status: Not listed — confirm with the team
  • Parc Sanitari Sant Joan de Deu (Sant Joan de Deu Serveis de Salut Mental)
    Barcelona
    Site status: Not listed — confirm with the team
  • Hospital Universitario Fundacion Jimenez Diaz
    Madrid
    Site status: Not listed — confirm with the team
  • FIDMAG Hermanas Hospitalarias
    Sant Boi de Llobregat
    Site status: Not listed — confirm with the team
  • Hospital Universitario Río Hortega de Valladolid
    Valladolid
    Site status: Not listed — confirm with the team
  • Hospital Provincial de Zamora - Servicio de Psiquiatria
    Zamora
    Site status: Not listed — confirm with the team
Sweden · 4 sites
  • Vuxenpsykiatrimottagningen
    Landskrona
    Site status: Not listed — confirm with the team
  • Lunds Universitet - Medicinska Fakulteten (Lund University Faculty of Medicine)
    Lund
    Site status: Not listed — confirm with the team
  • ClinSmart Sweden AB
    Solna
    Site status: Not listed — confirm with the team
  • Hälsoklustret
    Stockholm
    Site status: Not listed — confirm with the team
United Kingdom · 13 sites
  • Cornwall Partnership NHS Foundation Trust
    Bodmin, Cornwall
    Site status: Not listed — confirm with the team
  • Abraham Cowley Unit - Surrey and Borders Partnership NHS Foundation Trust
    Chertsey
    Site status: Not listed — confirm with the team
  • St. Pancras Clinical Research
    Chester
    Site status: Not listed — confirm with the team
  • Grounded Research Hub - Rotherham Doncaster & South Humber NHS Foundation Trust
    Doncaster
    Site status: Not listed — confirm with the team
  • Clinical Research Facility, Royal Devon and Exeter Hospital
    Exeter
    Site status: Not listed — confirm with the team
  • Fulbourn Hospital - Cambridgeshire And Peterborough NHS Foundation Trust
    Fulbourn
    Site status: Not listed — confirm with the team
  • St. Pancras Clinical Research
    London
    Site status: Not listed — confirm with the team
  • King's College London - Institute of Psychiatry, Psychology
    London
    Site status: Not listed — confirm with the team
  • Clerkenwell Health
    London
    Site status: Not listed — confirm with the team
  • Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust - Wolfson Research Centre
    Newcastle
    Site status: Not listed — confirm with the team
  • University Of Nottingham/Nottinghamshire Healthcare Trust, Institute Of Mental Health
    Nottingham
    Site status: Not listed — confirm with the team
  • The Warneford Hospital- NIHR Clinical Research Facility
    Oxford
    Site status: Not listed — confirm with the team
  • Sheffield Health and Social Care NHS Foundation Trust
    Sheffield
    Site status: Not listed — confirm with the team
United States · 62 sites
  • Lighthouse Psychiatry Scottsdale
    Gilbert, Arizona
    Site status: Not listed — confirm with the team
  • Clinical Innovations, Inc.
    Bellflower, California
    Site status: Not listed — confirm with the team
  • M3 Wake Research
    Encino, California
    Site status: Not listed — confirm with the team
  • The Regents of the University of California - San Diego
    La Jolla, California
    Site status: Not listed — confirm with the team
  • Kadima Neuropsychiatry Institute
    La Jolla, California
    Site status: Not listed — confirm with the team
  • CalNeuro Research Group, Inc
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • Catalina Research Institute, LLC
    Montclair, California
    Site status: Not listed — confirm with the team
  • Piedmont Hospital Neuroscience Centre
    Oakland, California
    Site status: Not listed — confirm with the team
  • ATP Clinical Research, Inc.
    Orange, California
    Site status: Not listed — confirm with the team
  • CITrials
    Riverside, California
    Site status: Not listed — confirm with the team
  • Lumos Clinical Research Center
    San Jose, California
    Site status: Not listed — confirm with the team
  • Syrentis Clinical Research
    Santa Ana, California
    Site status: Not listed — confirm with the team
  • Stanford University
    Stanford, California
    Site status: Not listed — confirm with the team
  • ASCLEPES Research Centers
    Thousand Oaks, California
    Site status: Not listed — confirm with the team
  • Pacific Clinical Research Management Group, LLC
    Upland, California
    Site status: Not listed — confirm with the team
  • Innovative Clinical Research, Inc.
    Lauderhill, Florida
    Site status: Not listed — confirm with the team
  • Central Miami Medical Institute, LLC
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Behavioral Clinical Research, Inc.
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Health Synergy Clinical Research
    Okeechobee, Florida
    Site status: Not listed — confirm with the team
  • Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • APG Research, LLC- Advanced Psychiatric Group
    Orlando, Florida
    Site status: Not listed — confirm with the team
  • University South Florida
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Stedman Clinical Trials
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Health Synergy Clinical Research, LLC
    West Palm Beach, Florida
    Site status: Not listed — confirm with the team
  • Atlanta Center for Medical Research
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • iResearch Atlanta
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Rush University Medical Center
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Uptown Research Institute, LLC
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Psychiatric Medicine Associates
    Skokie, Illinois
    Site status: Not listed — confirm with the team
  • Harvard Medical School - McLean Hospital
    Belmont, Massachusetts
    Site status: Not listed — confirm with the team
  • Adams Clinical - Boston (Copley Clinical)
    Boston, Massachusetts
    Site status: Not listed — confirm with the team
  • University of Massachusetts Medical School
    North Worcester, Massachusetts
    Site status: Not listed — confirm with the team
  • Adams Clinical - Boston
    Watertown, Massachusetts
    Site status: Not listed — confirm with the team
  • Michigan Clinical Research Institute PC
    Ann Arbor, Michigan
    Site status: Not listed — confirm with the team
  • University Of Michigan Comprehensive Depression Center
    Ann Arbor, Michigan
    Site status: Not listed — confirm with the team
  • Institute for Integrative Therapies
    Eden Prairie, Minnesota
    Site status: Not listed — confirm with the team
  • St. Charles Psychiatric Associates - Midwest Research Group
    Saint Charles, Missouri
    Site status: Not listed — confirm with the team
  • Alivation Research, LLC.
    Lincoln, Nebraska
    Site status: Not listed — confirm with the team
  • Hassman Research Institute
    Berlin, New Jersey
    Site status: Not listed — confirm with the team
  • Princeton Medical Institute
    Princeton, New Jersey
    Site status: Not listed — confirm with the team
  • Bio Behavioral Health
    Toms River, New Jersey
    Site status: Not listed — confirm with the team
  • Dent Neurosciences Research Center, Inc.
    Amherst, New York
    Site status: Not listed — confirm with the team
  • Fieve Clinical Research, Inc
    New York, New York
    Site status: Not listed — confirm with the team
  • Spectrum Neuroscience and Treatment Institute
    New York, New York
    Site status: Not listed — confirm with the team
  • Adams Clinical - New York
    New York, New York
    Site status: Not listed — confirm with the team
  • New York State Psychiatric Institute
    New York, New York
    Site status: Not listed — confirm with the team
  • Richmond Behavioral Associates
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • Adams Clinical - New York
    The Bronx, New York
    Site status: Not listed — confirm with the team
  • University of Cincinnati, Department of Psychiatry & Behavirol Neuroscience
    Cincinnati, Ohio
    Site status: Not listed — confirm with the team
  • Cleveland Clinic - Lutheran Hospital
    Cleveland, Ohio
    Site status: Not listed — confirm with the team
  • The Ohio State University
    Columbus, Ohio
    Site status: Not listed — confirm with the team
  • Suburban Research Associates
    Media, Pennsylvania
    Site status: Not listed — confirm with the team
  • The University of Texas at Austin - Dell Medical School
    Austin, Texas
    Site status: Not listed — confirm with the team
  • Houston Clinical Trials, LLC
    Bellaire, Texas
    Site status: Not listed — confirm with the team
  • Relaro Medical Trials
    Dallas, Texas
    Site status: Not listed — confirm with the team
  • Center for Depression Research and Clinical Care
    Dallas, Texas
    Site status: Not listed — confirm with the team
  • North Texas Clinical Trials
    Fort Worth, Texas
    Site status: Not listed — confirm with the team
  • Brain Health Consultants and TMS Center
    Houston, Texas
    Site status: Not listed — confirm with the team
  • HCA Healthcare Research Institute - Medical City Green Oaks Hospital
    Plano, Texas
    Site status: Not listed — confirm with the team
  • Cedar Clinical Research
    Draper, Utah
    Site status: Not listed — confirm with the team
  • The University of Utah - Huntsman Mental Health Institute
    Salt Lake City, Utah
    Site status: Not listed — confirm with the team
  • Seattle Neuropsychiatric Treatment Center
    Seattle, Washington
    Site status: Not listed — confirm with the team

Ask HopeStage to help me review this study

This record does not confirm open recruitment. We can help you understand it and explore other studies.

Loading the security check...
Study ID: NCT05711940. We help you review the study, but cannot decide medical eligibility.
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Psilocybin. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: Over 18 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by COMPASS Pathways, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

Explore other studies

Want to find a study that may fit you better?

Answer a few simple questions to explore HopeStage studies by condition, country, and situation.

Find a study that may fit me
Related studies

Explore related studies

Other studies that may be relevant based on condition, country, or study type.