RecruitingNCT05895747
5-HTP plus creatine added to usual treatment for treatment-resistant depression
About this title
Read the official source — NCT05895747Medication studyAges 18–65United States
Understand this study
Who could participate?
This study is for people with depression. Listed age limits: 18 years to 65 years. Other eligibility criteria apply.
What will I do during this study?
Participants are randomly assigned to one of three groups for eight weeks: two dose combinations of 5-HTP and creatine, or matching placebos. The study also includes brain imaging and blood tests.
- Listed locations
- Salt Lake CitySee all locations and recruitment
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Treatment duration
- The assigned tablet or placebo (an inactive comparison treatment) regimen lasts eight weeks
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: September 28, 2023
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 106
- Sponsor
- University of Utah
- Sponsor type
- University
- Study type
- Drug
- Intervention type
- Medication / drug
- Study phase
- Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
- Locations
- United States
- Age range
- From 18 Years to 65 Years
- Official registry ID
- NCT05895747
- Official title
Show the full official title
31P-MRS and Resting State Functional Connectivity Analysis of the Effects of 5-hydroxytryptophan and Creatine for Antidepressant Augmentation in Patients With SSRI/SNRI-resistant Major Depressive Disorder
Recruitment & locations
RecruitingSalt Lake City
A listed location does not confirm current availability.
Questions about this study
Who is behind this study?
The study sponsor is University of Utah, a university.
Does this study involve medication?
Yes. The study involves medication, including Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate, High Dose Creatine Monohydrate and Placebo.
Who can participate?
This study is for people with depression. Listed age limits: 18 years to 65 years. Other eligibility criteria apply.
Is this study still recruiting?
The registry lists this study as recruiting.
