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RecruitingNCT06529029

Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy

This study is recruiting. It focuses on depression and currently lists participation information in the United States.

DepressionDeviceFrom 18 Years to 90 Years
In plain English

Key information made simple

This study is looking at whether Sigma-Stim can help people with Suicidal Ideation, depression, Schizo Affective Disorder, or bipolarity. Participants take part in Sigma-Stim and complete follow-up assessments. Taking part may give some people access to Sigma-Stim, but direct benefit is not guaranteed.

What to expect

Your next step

The official record suggests in-person participation through a lab, with sites including Pine Rest Christian Mental Health Services in Grand Rapids. Participation appears to involve guided sessions or support activities with check-ins on how they fit into daily life. The main fit is usually matching the main diagnosis and being able to understand the study and consent, while common reasons not to take part include pregnancy or breastfeeding and safety concerns that need urgent care first. This is an early-stage study, which usually means a smaller group and a focus on learning how the approach behaves.

Public study data

Key study information

Official title
Efficacy of Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy in Remission of Suicidal Ideation
Condition
Suicidal Ideation; Major Depressive Disorder; Schizo Affective Disorder; Bipolar Disorder
Study status
Recruiting
Phase
Phase 2
Sponsor / lead affiliation
Michigan State University
Intervention
Sigma-Stim
Location / country
United States
Contact
Nagy A Youssef, MD, PhD, Janelle M Kassien, LMSW
Email
nagy.youssef@pinerest.org, janelle.kassien@pinerest.org
Phone
616-281-6451, 616-980-7516
Registry
ClinicalTrials.gov
Why this study may matter

Why this study may matter

This study may matter because it is evaluating Sigma-Stim in a structured research setting. For people exploring bipolarity research, clear information about the goal, status, contacts, and official source can support better questions before any decision.

Before joining

Questions to ask before joining

Official source

Registry reference

This page links back to the public source record so people can verify details directly with the registry and research team.

If you want the full study description, eligibility criteria, locations, and sponsor information in the original format, this is the place to check before taking the next step.

Open source record
Need help deciding?

Ask HopeStage to review this study with me

This form records your interest so HopeStage can follow up with practical guidance. It is not a medical eligibility decision and it does not guarantee a study spot.

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In practice

For you

Taking part may give access to a new approach being evaluated.

It requires regular follow-up, often through questionnaires or interviews.

Requires travel, with in-person participation in United States.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

Study clarity

Things to check before joining

Sponsor
Michigan State University
Sponsor type
University
Main activity
medical device
Intervention
Sigma-Stim
Time commitment
multiple visits or assessments
Study phase
Phase 2
Enrollment
Not available
Recruitment status
Recruiting
Source
Official registry link
FAQ

Questions about this study

What is Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy?

This study is exploring medical device for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed.

Who is behind this study, and what type of sponsor is it?

This study is sponsored by Michigan State University. Based on the sponsor name or official registry information, it appears to be a university. You should verify the details in the official registry record.

What does participation involve, what phase is it, and what should I ask about safety?

This study may involve medical device, study visits, and assessments. The time commitment is multiple visits or assessments. The study phase is Phase 2. Earlier-phase studies are often more focused on safety, dose, or feasibility, while later-phase studies usually involve more participants and more information about the intervention. The official source record gives the most accurate details. Enrollment is not available in HopeStage data. HopeStage cannot say whether a study is safe or right for you. Before joining, ask the research team about possible risks, time commitment, visits, side effects, compensation, safety monitoring, and whether participation may affect your current care.

Where can I verify the study details?

Use the official source record linked on this page to check the full study description, recruitment status, eligibility criteria, locations, sponsor information, phase, enrollment, contact details, and any listed risks or requirements.

Low Amplitude Pulse Seizure Therapy Versus. — Depression Clinical Trial | HopeStage