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SuspendedNCT06705478

Pramipexole ER for depression

This study is suspended in the United States, in Botswana, in Brazil, .... It is testing Pramipexole ER for depression.

Depression, Mild Neurocognitive Disorder, ...DrugFrom 18 Years to 70 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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In plain English

Key information made simple

What is this study testing?

This study is testing whether Pramipexole Versus Escitalopram may be useful for adults experiencing depression.

What would participation involve?

Participants may receive Pramipexole Versus Escitalopram, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Botswana, in Brazil, and in India.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)

  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: May 17, 2026
Recruitment status
Suspended
Enrollment listed in the registry
186
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Sponsor type
Research institute
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States, Botswana, Brazil, ...
Age range
From 18 Years to 70 Years
Official registry ID
NCT06705478
Official title
An Open-Label, Randomized Controlled Trial of Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Botswana · 1 site
  • Gaborone CRS
    Gaborone
    Site status: Not listed — confirm with the team
Brazil · 2 sites
  • Instituto de Pesquisas em AIDS do Rio Grande do Sul - IPARGS CRS
    Porto Alegre, Rio Grande do Sul
    Site status: Not listed — confirm with the team
  • Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS
    Rio de Janeiro
    Site status: Not listed — confirm with the team
India · 1 site
  • Byramjee Jeejeebhoy Medical College (BJMC) CRS
    Pune, Maharashtra
    Site status: Not listed — confirm with the team
Kenya · 2 sites
  • Moi University Clinical Research Center (MUCRC) CRS
    Eldoret, Rift Valley
    Site status: Not listed — confirm with the team
  • Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS
    Kericho, Rift Valley
    Site status: Not listed — confirm with the team
Malawi · 1 site
  • Blantyre CRS
    Blantyre
    Site status: Not listed — confirm with the team
Mexico · 1 site
  • Nutrición-Mexico CRS
    Mexico City, Tlalpan
    Site status: Not listed — confirm with the team
Peru · 1 site
  • Barranco CRS
    Lima
    Site status: Not listed — confirm with the team
Philippines · 1 site
  • De La Salle Medical and Health Sciences Institute - Angelo King Medical Research Center (DLSMHSI-AKMRC)
    Dasmariñas, Cavite
    Site status: Not listed — confirm with the team
South Africa · 1 site
  • Durban International CRS
    Mount Edgecombe
    Site status: Not listed — confirm with the team
Thailand · 2 sites
  • Thai Red Cross AIDS Research Centre (TRC-ARC) CRS
    Pathum Wan, Bangkok
    Site status: Not listed — confirm with the team
  • Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS
    Chiang Mai
    Site status: Not listed — confirm with the team
Uganda · 1 site
  • Joint Clinical Research Centre (JCRC)/Kampala CRS
    Kampala
    Site status: Not listed — confirm with the team
United States · 25 sites
  • Alabama CRS
    Birmingham, Alabama
    Site status: Not listed — confirm with the team
  • University of California, Los Angeles CARE Center CRS
    Los Angeles, California
    Site status: Not listed — confirm with the team
  • UCSD Antiviral Research Center CRS
    San Diego, California
    Site status: Not listed — confirm with the team
  • University of California, San Francisco HIV/AIDS CRS
    San Francisco, California
    Site status: Not listed — confirm with the team
  • Harbor University of California, Los Angeles Center CRS
    Torrance, California
    Site status: Not listed — confirm with the team
  • University of Colorado Hospital CRS
    Aurora, Colorado
    Site status: Not listed — confirm with the team
  • Whitman-Walker Institute, Inc. CRS
    Washington D.C., District of Columbia
    Site status: Not listed — confirm with the team
  • The Ponce de Leon Center CRS
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • Northwestern University CRS
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Massachusetts General Hospital CRS (MGH CRS)
    Boston, Massachusetts
    Site status: Not listed — confirm with the team
  • Washington University Therapeutics (WT) CRS
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • New Jersey Medical School Clinical Research Center CRS (Site ID 31786)
    Newark, New Jersey
    Site status: Not listed — confirm with the team
  • Weill Cornell Chelsea CRS
    New York, New York
    Site status: Not listed — confirm with the team
  • Columbia Physicians & Surgeons (P&S) CRS
    New York, New York
    Site status: Not listed — confirm with the team
  • Weill Cornell Uptown CRS
    New York, New York
    Site status: Not listed — confirm with the team
  • University of Rochester Adult HIV Therapeutic Strategies Network CRS
    Rochester, New York
    Site status: Not listed — confirm with the team
  • Chapel Hill CRS
    Chapel Hill, North Carolina
    Site status: Not listed — confirm with the team
  • Greensboro CRS
    Greensboro, North Carolina
    Site status: Not listed — confirm with the team
  • Cincinnati CRS
    Cincinnati, Ohio
    Site status: Not listed — confirm with the team
  • Case CRS
    Cleveland, Ohio
    Site status: Not listed — confirm with the team
  • Ohio State University CRS
    Columbus, Ohio
    Site status: Not listed — confirm with the team
  • Penn Therapeutics CRS
    Philadelphia, Pennsylvania
    Site status: Not listed — confirm with the team
  • University of Pittsburgh CRS
    Pittsburgh, Pennsylvania
    Site status: Not listed — confirm with the team
  • Vanderbilt Therapeutics (VT) CRS
    Nashville, Tennessee
    Site status: Not listed — confirm with the team
  • Houston Advancing Research Team CRS
    Houston, Texas
    Site status: Not listed — confirm with the team
Vietnam · 1 site
  • Hanoi Medical University (HMU)
    Hanoi
    Site status: Not listed — confirm with the team
Zimbabwe · 1 site
  • Milton Park CRS
    Milton Park, Harare
    Site status: Not listed — confirm with the team
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Pramipexole ER, Escitalopram. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 70 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which appears to be a research institute. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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