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SuspendedNCT06705478

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Medication studyAges 18–70Multiple countriesDepression
The study in practice

Understand this study

Who could participate?

Listed age limits: 18 years to 70 years.

Listed locations
Birmingham and 40 more locationsSee all locations and recruitment
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.

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What to know before participating

A point to clarify

This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?

Study clarity

Things to check before joining

Study start dateStarted: May 17, 2026
Recruitment status
Suspended
Enrollment listed in the registry
186
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Sponsor type
Research institute
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States, Botswana, Brazil, ...
Age range
From 18 Years to 70 Years
Official registry ID
NCT06705478
Official title
Show the full official title

An Open-Label, Randomized Controlled Trial of Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Recruitment & locations

Suspended

Birmingham, United States · Los Angeles, United States · San Diego, United States

36 more locations
  • San Francisco, United States
  • Torrance, United States
  • Aurora, United States
  • Washington D.C., United States
  • Atlanta, United States
  • Chicago, United States
  • Boston, United States
  • St Louis, United States
  • Newark, United States
  • New York, United States
  • Rochester, United States
  • Chapel Hill, United States
  • Greensboro, United States
  • Cincinnati, United States
  • Cleveland, United States
  • Columbus, United States
  • Philadelphia, United States
  • Pittsburgh, United States
  • Nashville, United States
  • Houston, United States
  • Gaborone, Botswana
  • Porto Alegre, Brazil
  • Rio de Janeiro, Brazil
  • Pune, India
  • Eldoret, Kenya
  • Kericho, Kenya
  • Blantyre, Malawi
  • Mexico City, Mexico
  • Lima, Peru
  • Dasmariñas, Philippines
  • Mount Edgecombe, South Africa
  • Pathum Wan, Thailand
  • Chiang Mai, Thailand
  • Kampala, Uganda
  • Hanoi, Vietnam
  • Milton Park, Zimbabwe

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FAQ

Questions about this study

Who is behind this study?

The study sponsor is National Institute of Allergy and Infectious Diseases (NIAID), a research institute.

Does this study involve medication?

Yes. The study involves medication, including Pramipexole ER and Escitalopram.

Who can participate?

Listed age limits: 18 years to 70 years.

Is this study still recruiting?

The registry lists this study as suspended.

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