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RecruitingNCT06775379

Study to Evaluate Azetukalner in Moderate-to-Severe Major Depressive Disorder

The registry lists this study as recruiting. Study locations are listed in the United States. Confirm recruitment at each site. It is testing azetukalner for depression.

DepressionDrugFrom 18 Years to 74 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether Azetukalner Versus Placebo may be useful for adults experiencing depression.

What would participation involve?

Participants may receive Azetukalner Versus Placebo, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: December 20, 2024
Recruitment status
Recruiting
Enrollment listed in the registry
450
Sponsor
Xenon Pharmaceuticals Inc.
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States
Age range
From 18 Years to 74 Years
Official registry ID
NCT06775379
Official title
A Phase 3, Randomized, Double-blind, Placebo-Controlled, Multicenter Study to Evaluate Azetukalner in Moderate-to-Severe Major Depressive Disorder

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 51 sites
  • IMA Clinical Research Phoenix
    Phoenix, Arizona
    Site status: Recruiting
  • Woodland International Research Group
    Little Rock, Arkansas
    Site status: Recruiting
  • Woodland Research Northwest
    Rogers, Arkansas
    Site status: Recruiting
  • Behavioral Research Specialists, Llc
    Glendale, California
    Site status: Recruiting
  • Marvel Clinical Research
    Huntington Beach, California
    Site status: Withdrawn
  • Irvine Clinical Research
    Irvine, California
    Site status: Recruiting
  • CalNeuro Research Group, Inc.
    Los Angeles, California
    Site status: Recruiting
  • Excell Research Inc.
    Oceanside, California
    Site status: Recruiting
  • Atp Clinical Research
    Orange, California
    Site status: Recruiting
  • Nrc Research Institute
    Orange, California
    Site status: Recruiting
  • CenExel CNS-TO (Collaborative Neuroscience Research)
    Torrance, California
    Site status: Recruiting
  • Sunwise Clinical Research
    Walnut Creek, California
    Site status: Recruiting
  • Kinetic Clinical Research, LLC
    West Covina, California
    Site status: Recruiting
  • Mountain View Clinical Research
    Denver, Colorado
    Site status: Recruiting
  • Ct Clinical Research Associates
    Cromwell, Connecticut
    Site status: Recruiting
  • CNS Clinical Research Group
    Coral Springs, Florida
    Site status: Recruiting
  • NeoClinical Research
    Hialeah, Florida
    Site status: Active Not Recruiting
  • Clinical Neuroscience Solutions, Inc.
    Jacksonville, Florida
    Site status: Recruiting
  • Accel Research Sites Lakeland
    Lakeland, Florida
    Site status: Recruiting
  • Accel Research Sites - St. Petersburg-Largo
    Largo, Florida
    Site status: Recruiting
  • PharmaSouth Research
    Miami, Florida
    Site status: Recruiting
  • Quantum Clinical Trials
    Miami Beach, Florida
    Site status: Terminated
  • Harmony Clinical Research Inc
    North Miami Beach, Florida
    Site status: Active Not Recruiting
  • Clinical Neuroscience Solutions, Inc.
    Orlando, Florida
    Site status: Recruiting
  • Combined Research Orlando Phase I-Iv
    Orlando, Florida
    Site status: Active Not Recruiting
  • Panhandle Research and Medical Clinic
    Pensacola, Florida
    Site status: Recruiting
  • Advanced Discovery Research
    Atlanta, Georgia
    Site status: Recruiting
  • Synexus - Atlanta
    Atlanta, Georgia
    Site status: Recruiting
  • CenExel iResearch
    Decatur, Georgia
    Site status: Active Not Recruiting
  • Psych Atlanta, Pc
    Marietta, Georgia
    Site status: Recruiting
  • Cenexel Iresearch - Savannah
    Savannah, Georgia
    Site status: Recruiting
  • Northwest Clinical Trials Inc
    Boise, Idaho
    Site status: Recruiting
  • IMA Clinical Research
    Chicago, Illinois
    Site status: Active Not Recruiting
  • Boston Clinical Trials Llc
    Boston, Massachusetts
    Site status: Recruiting
  • ELIXIA
    Springfield, Massachusetts
    Site status: Recruiting
  • Tekton Research
    St Louis, Missouri
    Site status: Recruiting
  • IMA Clinical Research Las Vegas
    Las Vegas, Nevada
    Site status: Recruiting
  • Redbird Research
    Las Vegas, Nevada
    Site status: Active Not Recruiting
  • IMA Clinical Research
    Albuquerque, New Mexico
    Site status: Recruiting
  • Integrative Clinical Trials
    Brooklyn, New York
    Site status: Recruiting
  • Richmond Behavioral Associates
    Staten Island, New York
    Site status: Recruiting
  • New Hope Clinical Research
    Charlotte, North Carolina
    Site status: Recruiting
  • Neuro-Behavioral Clinical Research
    North Canton, Ohio
    Site status: Recruiting
  • Pahl Pharmaceutical Professionals Llc
    Oklahoma City, Oklahoma
    Site status: Recruiting
  • Lehigh Center For Clinical Research
    Allentown, Pennsylvania
    Site status: Recruiting
  • Adams Clinical - Philadelphia
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Clinical Neuroscience Solutions, Inc.
    Memphis, Tennessee
    Site status: Recruiting
  • Delricht Research - Plano
    Plano, Texas
    Site status: Recruiting
  • Aim Trials, Llc
    Plano, Texas
    Site status: Recruiting
  • Grayline Research Center
    Wichita Falls, Texas
    Site status: Recruiting
  • Core Clinical Research
    Everett, Washington
    Site status: Recruiting
Study drug

About the molecule

When a study medicine is clearly identified, HopeStage adds a short explanation of what that molecule is and links back to reliable public sources.

Azetukalner

an experimental Kv7 potassium-channel opener

targets Kv7 potassium channels

In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring the study treatment Azetukalner for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Azetukalner, Placebo. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 74 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Xenon Pharmaceuticals Inc., which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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