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CompletedNCT06785012

Safety study of Efficacy, Safety, and Tolerability of JNJ-89495120 in depression

This study is completed in the United States. It is testing Efficacy, Safety, and Tolerability of JNJ-89495120 for depression.

DepressionDrugFrom 18 Years to 64 Years

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  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

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Study start dateStarted: December 26, 2024
Recruitment status
Completed
Enrollment listed in the registry
107
Sponsor
Janssen Research & Development, LLC
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States
Age range
From 18 Years to 64 Years
Official registry ID
NCT06785012
Official title
A Randomized, Double-blind, Multicenter, Placebo-controlled, Proof-of-Concept Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-89495120 as Monotherapy in Adult Participants With Major Depressive Disorder (MDD)

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

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The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 44 sites
  • UAB Huntsville Regional Medical Campus
    Huntsville, Alabama
    Site status: Not listed — confirm with the team
  • Chandler Clinical Trials
    Chandler, Arizona
    Site status: Not listed — confirm with the team
  • IMA Clinical Research PC Phoenix
    Phoenix, Arizona
    Site status: Not listed — confirm with the team
  • Noble Clinical Research
    Tucson, Arizona
    Site status: Not listed — confirm with the team
  • University of Arizona
    Tucson, Arizona
    Site status: Not listed — confirm with the team
  • CI Trials
    Bellflower, California
    Site status: Not listed — confirm with the team
  • Wake Research PRI Encino
    Encino, California
    Site status: Not listed — confirm with the team
  • National Institute Of Clinical Research
    Garden Grove, California
    Site status: Not listed — confirm with the team
  • WR-Newport Beach
    Newport Beach, California
    Site status: Not listed — confirm with the team
  • ATP Clinical Research
    Orange, California
    Site status: Not listed — confirm with the team
  • Anderson Clinical Research
    Redlands, California
    Site status: Not listed — confirm with the team
  • Artemis Institute for Clinical Research
    San Diego, California
    Site status: Not listed — confirm with the team
  • Lumos Clinical Research Center LLC
    San Jose, California
    Site status: Not listed — confirm with the team
  • Syrentis Clinical Research
    Santa Ana, California
    Site status: Not listed — confirm with the team
  • Inland Psychiatric Medical Group Inc
    Temecula, California
    Site status: Not listed — confirm with the team
  • Sunwise Clinical Research
    Walnut Creek, California
    Site status: Not listed — confirm with the team
  • Mountain View Clinical Research
    Denver, Colorado
    Site status: Not listed — confirm with the team
  • Gulfcoast Medical Research Center
    Fort Myers, Florida
    Site status: Not listed — confirm with the team
  • The Medici Medical Research
    Hollywood, Florida
    Site status: Not listed — confirm with the team
  • Advanced Research Institute of Miami
    Homestead, Florida
    Site status: Not listed — confirm with the team
  • K2 Medical Research
    Maitland, Florida
    Site status: Not listed — confirm with the team
  • Pharmax Research Clinic Inc
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Wellness Research Center
    Miami, Florida
    Site status: Not listed — confirm with the team
  • Best Choice Medical and Research Service
    Pembroke Pines, Florida
    Site status: Not listed — confirm with the team
  • Interventional Psychiatry of Tampa Bay
    Tampa, Florida
    Site status: Not listed — confirm with the team
  • Health Synergy Clinical Research
    West Palm Beach, Florida
    Site status: Not listed — confirm with the team
  • Synexus Clinical Research US Inc
    Atlanta, Georgia
    Site status: Not listed — confirm with the team
  • iResearch Atlanta LLC
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Accelerated Clinical Research Group LLC
    Snellville, Georgia
    Site status: Not listed — confirm with the team
  • University of Chicago Medical Center
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • Indiana University IU Health
    Indianapolis, Indiana
    Site status: Not listed — confirm with the team
  • DelRicht Research
    New Orleans, Louisiana
    Site status: Not listed — confirm with the team
  • CBH Health
    Gaithersburg, Maryland
    Site status: Not listed — confirm with the team
  • University of Massachusetts Medical School
    Worcester, Massachusetts
    Site status: Not listed — confirm with the team
  • Integrative Clinical Trials LLC
    Brooklyn, New York
    Site status: Not listed — confirm with the team
  • Patient Priority Clinical Sites LLC
    Cincinnati, Ohio
    Site status: Not listed — confirm with the team
  • University of Cincinnati
    Cincinnati, Ohio
    Site status: Not listed — confirm with the team
  • OSU Department of Psychiatry and Behavioral Health
    Columbus, Ohio
    Site status: Not listed — confirm with the team
  • Paradigm Research Professionals, LLC
    Oklahoma City, Oklahoma
    Site status: Not listed — confirm with the team
  • University of Pennsylvania
    Philadelphia, Pennsylvania
    Site status: Not listed — confirm with the team
  • Coastal Carolina Research Center
    North Charleston, South Carolina
    Site status: Not listed — confirm with the team
  • Revival Research Institute LLC
    McKinney, Texas
    Site status: Not listed — confirm with the team
  • Alpine Research Organization
    Clinton, Utah
    Site status: Not listed — confirm with the team
  • Core Clinical Research
    Everett, Washington
    Site status: Not listed — confirm with the team

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Study ID: NCT06785012. We help you review the study, but cannot decide medical eligibility.
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving JNJ-89495120, Placebo. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 64 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Janssen Research & Development, LLC, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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