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RecruitingNCT06793397

CYB003 for depression

The registry lists this study as recruiting. Study locations are listed in the United States, in Australia, in the United Kingdom, ... Confirm recruitment at each site. It is testing CYB003 for depression.

DepressionBehavioralFrom 18 Years to 85 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether CYB003 may be useful for adults experiencing depression.

What would participation involve?

Participants may receive CYB003, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Australia, in Czechia, and in Germany.

Who is it mainly for?

This study appears to be mainly for adults with depression.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: December 10, 2025
Recruitment status
Recruiting
Enrollment listed in the registry
330
Sponsor
Cybin IRL Limited
Sponsor type
Unknown or unclear
Study type
Behavioral
Intervention type
Psychotherapy / behavioral intervention, Medication / drug
Study phase
Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
Locations
United States, Australia, United Kingdom, ...
Age range
From 18 Years to 85 Years
Official registry ID
NCT06793397
Official title
An Efficacy and Safety, Phase III, Multi-center, Double-Blind, Randomized Controlled Study Comparing 2 Active Doses of CYB003 and Placebo in Eligible Participants With Major Depressive Disorder

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Australia · 5 sites
  • Royal Prince Alfred Hospital
    Camperdown, New South Wales
    Site status: Recruiting
  • Thompson Brain & Mind Healthcare (TBMH)
    Maroochydore, Queensland
    Site status: Recruiting
  • Ramsay Clinic
    Melbourne, Victoria
    Site status: Recruiting
  • Neurocentrix Research
    Melbourne, Victoria
    Site status: Recruiting
  • Monash University - Notting Hill
    Notting Hill, Victoria
    Site status: Recruiting
Czechia · 3 sites
  • Institute of neuropsychiatric Care (INEP)
    Prague
    Site status: Not Yet Recruiting
  • Psyon s.r.o.
    Prague
    Site status: Not Yet Recruiting
  • A-SHINE s.r.o.
    Předměstí
    Site status: Not Yet Recruiting
Germany · 4 sites
  • Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes
    Homburg, Saarland
    Site status: Not Yet Recruiting
  • Charité Universitaetsmedizin Berlin
    Berlin
    Site status: Not Yet Recruiting
  • University Hospital Frankfurt
    Frankfurt am Main
    Site status: Not Yet Recruiting
  • Central Institute of Mental Health
    Mannheim
    Site status: Not Yet Recruiting
Greece · 3 sites
  • Eginitio Hospital
    Athens
    Site status: Recruiting
  • Attikon University Hospital
    Athens
    Site status: Recruiting
  • Papageorgiou General Hospital
    Thessaloniki
    Site status: Recruiting
Ireland · 2 sites
  • Sheaf House - Tallaght Adult Mental Health Service
    Dublin
    Site status: Recruiting
  • La Nua Day Hospital Mental Health Centre
    Galway
    Site status: Recruiting
Poland · 6 sites
  • Uniwersytecki Szpital Kliniczny W Białymstoku
    Bialystok
    Site status: Not Yet Recruiting
  • Promente - Centrum Neurologii i Psychogeriatrii w Bydgoszczy
    Bydgoszcz
    Site status: Recruiting
  • UCK
    Gdansk
    Site status: Not Yet Recruiting
  • Centrum Badan Klinicznych PI-House Sp. z o.o
    Gdansk
    Site status: Recruiting
  • MTZ Clinical Research Powered by Pratia
    Warsaw
    Site status: Recruiting
  • Department of Pharmacology and Physiology of CNS
    Warsaw
    Site status: Not Yet Recruiting
United Kingdom · 12 sites
  • Cambridge University Hospital NHS
    Cambridge
    Site status: Recruiting
  • Clerkenwell Health - Doncaster
    Doncaster
    Site status: Recruiting
  • NHS Research Scotland
    Edinburgh
    Site status: Not Yet Recruiting
  • Queen Elizabeth University Hospital
    Glasgow
    Site status: Not Yet Recruiting
  • St Pancras Clinical Research
    London
    Site status: Recruiting
  • King's College London
    London
    Site status: Recruiting
  • Clerkenwell Health - Welbeck Street
    London
    Site status: Withdrawn
  • Re:Cognition Health
    London
    Site status: Recruiting
  • Clerkenwell Health - Baker Street
    London
    Site status: Recruiting
  • Edwardson Building - Campus for Ageing and Vitality
    Newcastle upon Tyne
    Site status: Recruiting
  • Ascend Clinical Research
    Reading
    Site status: Recruiting
  • Sheffield Health and Social Care NHS Foundation Trust
    Sheffield
    Site status: Recruiting
United States · 34 sites
  • UAB Psychiatry and Behavioral Neurology
    Birmingham, Alabama
    Site status: Recruiting
  • Lighthouse Psychiatry
    Gilbert, Arizona
    Site status: Recruiting
  • Pillar Clinical Research - Little Rock
    Little Rock, Arkansas
    Site status: Withdrawn
  • Behavioral Research Specialists, LLC
    Glendale, California
    Site status: Recruiting
  • Sun Valley Research Center
    Imperial, California
    Site status: Withdrawn
  • CalNeuro Research Group
    Los Angeles, California
    Site status: Recruiting
  • ATP Clinical Research
    Orange, California
    Site status: Recruiting
  • NRC Research Institute
    Orange, California
    Site status: Recruiting
  • Inland Psychiatric Medical Group Inc (IPMG Research)
    San Juan Capistrano, California
    Site status: Not Yet Recruiting
  • Psychedelic Science Institute
    Santa Monica, California
    Site status: Recruiting
  • Stanford University
    Stanford, California
    Site status: Withdrawn
  • Yale School of Medicine - Yale Program for Psychedelic Science
    New Haven, Connecticut
    Site status: Recruiting
  • CNS Healthcare
    Jacksonville, Florida
    Site status: Recruiting
  • Accel Research Sites - Maitland
    Maitland, Florida
    Site status: Recruiting
  • Aqualane Clinical Research
    Naples, Florida
    Site status: Recruiting
  • Emory University Dept of Psychiatry and Behavioral Studies
    Atlanta, Georgia
    Site status: Not Yet Recruiting
  • Psych Atlanta
    Marietta, Georgia
    Site status: Recruiting
  • Rush University
    Chicago, Illinois
    Site status: Recruiting
  • Tandem Clinical Research
    Marrero, Louisiana
    Site status: Not Yet Recruiting
  • Atlas Psychiatry
    New Orleans, Louisiana
    Site status: Recruiting
  • Johns Hopkins Medicine
    Baltimore, Maryland
    Site status: Not Yet Recruiting
  • Institute for Integrative Therapies
    Eden Prairie, Minnesota
    Site status: Recruiting
  • Redbird Research, LLC
    Las Vegas, Nevada
    Site status: Recruiting
  • Bio Behavioral Health
    Toms River, New Jersey
    Site status: Recruiting
  • New York State Psychiatric Institute
    New York, New York
    Site status: Not Yet Recruiting
  • SP Research PLLC
    Oklahoma City, Oklahoma
    Site status: Withdrawn
  • Adams Clinical Philadelphia
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Flourish Research Philadelphia
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Austin Clinical Trial Partners
    Austin, Texas
    Site status: Not Yet Recruiting
  • North Texas Clinical Trials
    Fort Worth, Texas
    Site status: Withdrawn
  • Brain Health Consultants and TMS Center
    Houston, Texas
    Site status: Recruiting
  • Flourish Research San Antonio
    San Antonio, Texas
    Site status: Recruiting
  • Core Clinical Research
    Everett, Washington
    Site status: Not Yet Recruiting
  • Seattle Neuropsychiatric Treatment Center
    Seattle, Washington
    Site status: Recruiting
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring psychotherapy or therapy for people with depression. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

What is a behavioral study?

This appears to be a behavioral / psychological / psychosocial study involving CYB003, Psychological Support. Phase 3 studies are usually larger and aim to confirm effectiveness and safety in a broader group.

Who might this study be for?

This study may concern people with depression; age range: From 18 Years to 85 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may take part in sessions or exercises related to habits, thoughts, emotions, or behaviors. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

Could this study affect my mood, habits, motivation, or stress?

Behavioral studies can involve habits, emotions, motivation, stress, sleep, or ways of thinking. Ask whether the intervention could affect your mood or stress, and who to contact if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Cybin IRL Limited, which appears to be unknown or unclear. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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