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Active Not RecruitingNCT07046494

RAP-219 for manic episodes in bipolarity type I

This study is active but not recruiting in the United States. It is testing RAP-219 for manic episodes in bipolarity type I.

BipolarityDrugFrom 18 Years to 65 Years

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

Then choose your country and confirm availability with each study site.

In plain English

Key information made simple

What is this study testing?

This study is testing whether RAP-219 may be useful for adults experiencing bipolarity.

What would participation involve?

Participants may receive RAP-219, complete questionnaires or follow-up assessments, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for adults with bipolarity.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: July 25, 2025
Recruitment status
Active Not Recruiting
Enrollment listed in the registry
253
Sponsor
Rapport Therapeutics Inc.
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug, OTHER
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States
Age range
From 18 Years to 65 Years
Official registry ID
NCT07046494
Official title
A Phase 2, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of RAP-219 for the Acute Treatment of Manic Episodes, With or Without Mixed Features, Associated With Bipolar I Disorder

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 20 sites
  • Pillar Clinical Research - Little Rock
    Little Rock, Arkansas
    Site status: Not listed — confirm with the team
  • Woodland Research Northwest
    Rogers, Arkansas
    Site status: Not listed — confirm with the team
  • Inland Psychiatric Medical Group - Chino
    Chino, California
    Site status: Not listed — confirm with the team
  • Synergy Clinical Research Center - San Diego
    Lemon Grove, California
    Site status: Not listed — confirm with the team
  • Collaborative Neuroscience Research - Los Alamitos
    Los Alamitos, California
    Site status: Not listed — confirm with the team
  • NRC Research Institute - Orange
    Orange, California
    Site status: Not listed — confirm with the team
  • NeuroBehavioral Hospitals of the Palm Beaches - South
    Boynton Beach, Florida
    Site status: Not listed — confirm with the team
  • United Research Institute
    Hialeah, Florida
    Site status: Not listed — confirm with the team
  • CenExel - Hollywood
    Hollywood, Florida
    Site status: Not listed — confirm with the team
  • Segal Trials - Miami Lakes Medical Research Early Phase, Inpatient & Outpatient Site
    Miami Lakes, Florida
    Site status: Not listed — confirm with the team
  • Neuroscience Research Institute at Ambrosia
    West Palm Beach, Florida
    Site status: Not listed — confirm with the team
  • CenExel - Decatur
    Decatur, Georgia
    Site status: Not listed — confirm with the team
  • Pillar Clinical Research - Chicago
    Chicago, Illinois
    Site status: Not listed — confirm with the team
  • CenExel - Gaithersburg
    Gaithersburg, Maryland
    Site status: Not listed — confirm with the team
  • Arch Clinical Trials
    St Louis, Missouri
    Site status: Not listed — confirm with the team
  • Richmond Behavioral Associates
    Staten Island, New York
    Site status: Not listed — confirm with the team
  • New Hope Clinical Research
    Charlotte, North Carolina
    Site status: Not listed — confirm with the team
  • Community Clinical Research, Inc.
    Austin, Texas
    Site status: Not listed — confirm with the team
  • HD Research - Memorial Hermann Village
    Houston, Texas
    Site status: Not listed — confirm with the team
  • Pillar Clinical Research - Richardson
    Richardson, Texas
    Site status: Not listed — confirm with the team
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with bipolarity. Participants may complete study visits, assessments, or follow-up activities defined by the research team. It includes a comparison with placebo. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving RAP-219, Placebo. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Who might this study be for?

This study may concern people with bipolarity; age range: From 18 Years to 65 Years. The criteria appear strict, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Rapport Therapeutics Inc., which appears to be a biotech company. The listed contact or investigator is Rapport Therapeutics Inc., affiliated with Rapport Therapeutics Inc.. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as not currently recruiting. This page remains available for information. Check the official record for the latest status and explore other recruiting studies.

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