RecruitingNCT07159061
Real-time brain feedback training for depression
About this title
Read the official source — NCT07159061Behavioural studyAges 18–65United States
Understand this study
Who could participate?
Listed age limits: 18 years to 65 years.
What will I do during this study?
This recruiting study is testing real-time fMRI neurofeedback for adults with major depression or bipolarity type II during a depressive episode. Participants receive active or sham (simulated) neurofeedback while researchers use brain imaging to study attention patterns and depressive symptoms. Participants must score at least 16 on a depression rating scale (MADRS). The study excludes people taking psychoactive medication or receiving therapy, as well as those with active suicide risk or MRI (magnetic resonance imaging) contraindications.
- Listed locations
- PhiladelphiaSee all locations and recruitment
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: November 21, 2025
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 80
- Sponsor
- University of Pennsylvania
- Sponsor type
- University
- Study type
- Behavioral
- Intervention type
- Psychotherapy / behavioral intervention
- Study phase
- Not clearly listed
- Locations
- United States
- Age range
- From 18 Years to 65 Years
- Official registry ID
- NCT07159061
- Official title
Show the full official title
Reducing Neural Perseveration Through Closed Loop Real Time fMRI Neurofeedback to Alleviate Depressive Symptoms
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Philadelphia
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is University of Pennsylvania, a university.
Who can participate?
Listed age limits: 18 years to 65 years.
Is this study still recruiting?
The registry lists this study as recruiting.
