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RecruitingNCT07226895

Safety study of MT1988 Low Dose in Clinical High Risk for Psychosis (CHR)

The registry lists this study as recruiting. Study locations are listed in the United States. Confirm recruitment at each site. It is testing MT1988 Low Dose for Clinical High Risk for Psychosis (CHR).

SchizophreniaDrugFrom 17 Years to 30 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether a blood test or biomarker may be useful for people experiencing schizophrenia.

What would participation involve?

Participants may complete a blood test or biomarker, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for people with schizophrenia.

What should you check before joining?

Ask about whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: March 3, 2026
Recruitment status
Recruiting
Enrollment listed in the registry
150
Sponsor
Monument Therapeutics Limited
Sponsor type
Biotech company
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 1, Phase 2This study spans more than one phase, so it may combine goals such as safety, dosing, and early effectiveness.
Locations
United States
Age range
From 17 Years to 30 Years
Official registry ID
NCT07226895
Official title
A Study to Explore Changes in Cognitive, Clinical, Biological and Digital Measures Following 8 Weeks of Twice-daily Dosing of MT1988 and to Evaluate Safety & Tolerability of MT1988, in Participants at Clinical High Risk (CHR) for Psychosis

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 15 sites
  • University of California, Irvine
    Irvine, California
    Site status: Recruiting
  • University of California
    Los Angeles, California
    Site status: Recruiting
  • University of California, San Francisco
    San Francisco, California
    Site status: Recruiting
  • Yale University Conneticut Mental Health Center
    New Haven, Connecticut
    Site status: Recruiting
  • Beth Israel Deaconess Medical Center
    Boston, Massachusetts
    Site status: Recruiting
  • Washington University
    St Louis, Missouri
    Site status: Recruiting
  • Northwell Health
    Glen Oaks, New York
    Site status: Recruiting
  • Columbia University
    New York, New York
    Site status: Recruiting
  • Icahan School of Medicine at Mount Sinai
    New York, New York
    Site status: Recruiting
  • University of North Carolina at Chapel Hill
    Chapel Hill, North Carolina
    Site status: Recruiting
  • Ohio State University
    Columbus, Ohio
    Site status: Recruiting
  • Prevention Science Institute
    Eugene, Oregon
    Site status: Recruiting
  • University of Pennsylvania
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Temple University
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • University of Pittsburgh School of Medicine
    Pittsburgh, Pennsylvania
    Site status: Recruiting
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with schizophrenia. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving MT1988 Low Dose, MT1988 High Dose, Placebo. Phase 1 studies usually focus mainly on safety, tolerability, dosage, and side effects. They often involve healthy volunteers, but not always. Some Phase 1 studies include people living with the target condition.

Who might this study be for?

This study may concern people with schizophrenia; age range: From 17 Years to 30 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Monument Therapeutics Limited, which appears to be a biotech company. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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