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RecruitingNCT07379827

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

This study is recruiting. It focuses on schizophrenia and currently lists participation information in the United States.

SchizophreniaDrugOver 18 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether Xanomeline and trospium chloride (KarXT) may be useful for adults experiencing schizophrenia.

What would participation involve?

Participants may receive Xanomeline and trospium chloride (KarXT), attend study visits with the research team. The registry lists locations in the United States.

Who is it mainly for?

This study appears to be mainly for adults with schizophrenia.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: February 26, 2026
Recruitment status
Recruiting
Enrollment listed in the registry
1,500
Sponsor
Bristol-Myers Squibb
Sponsor type
Pharmaceutical company
Study type
Drug
Intervention type
Medication / drug
Study phase
Not clearly listed
Locations
United States
Age range
Over 18 Years
Official registry ID
NCT07379827
Official title
Effectiveness and Adverse-effect Switch Evaluation

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Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

United States · 55 sites
  • SanRo Clinical Research Group
    Bryant, Arkansas
    Site status: Recruiting
  • Pamoja Advanced Nursing Practice
    Anaheim, California
    Site status: Recruiting
  • Local Institution - 0003
    Anaheim, California
    Site status: Not Yet Recruiting
  • Inland Psychiatric Medical Group (IPMG)-Chino
    Chino, California
    Site status: Recruiting
  • Local Institution - 0012
    La Palma, California
    Site status: Not Yet Recruiting
  • Local Institution - 0043
    Oceanside, California
    Site status: Not Yet Recruiting
  • Local Institution - 0028
    Stanford, California
    Site status: Not Yet Recruiting
  • Envision Trials LLC
    Bonita Springs, Florida
    Site status: Recruiting
  • Galiz Research
    Hialeah, Florida
    Site status: Recruiting
  • Local Institution - 0030
    Homestead, Florida
    Site status: Not Yet Recruiting
  • New Access Research & Medical Services Inc - Kendall
    Kendall, Florida
    Site status: Recruiting
  • Local Institution - 0032
    Miami, Florida
    Site status: Not Yet Recruiting
  • Banyan Behavioal Care Program - CSU
    Miami, Florida
    Site status: Recruiting
  • Local Institution - 0007
    Miami, Florida
    Site status: Not Yet Recruiting
  • BioResearch Partner - Miami
    Miami, Florida
    Site status: Recruiting
  • Medical Research of Central Florida
    Orange City, Florida
    Site status: Recruiting
  • Local Institution - 0040
    Orlando, Florida
    Site status: Not Yet Recruiting
  • Emory University.
    Atlanta, Georgia
    Site status: Recruiting
  • Local Institution - 0049
    Austell, Georgia
    Site status: Not Yet Recruiting
  • Local Institution - 0044
    Marietta, Georgia
    Site status: Not Yet Recruiting
  • Local Institution - 0046
    Crystal Lake, Illinois
    Site status: Not Yet Recruiting
  • Amr Conventions Research - Illinois
    Warrenville, Illinois
    Site status: Recruiting
  • Local Institution - 0014
    Bloomfield Township, Michigan
    Site status: Not Yet Recruiting
  • Local Institution - 0036
    Detroit, Michigan
    Site status: Not Yet Recruiting
  • Local Institution - 0034
    Apple Valley, Minnesota
    Site status: Not Yet Recruiting
  • Local Institution - 0054
    Duluth, Minnesota
    Site status: Not Yet Recruiting
  • Local Institution - 0041
    Lincoln, Nebraska
    Site status: Not Yet Recruiting
  • Local Institution - 0055
    Las Vegas, Nevada
    Site status: Not Yet Recruiting
  • Local Institution - 0037
    Buffalo, New York
    Site status: Not Yet Recruiting
  • Local Institution - 0004
    Monsey, New York
    Site status: Not Yet Recruiting
  • Local Institution - 0038
    Rochester, New York
    Site status: Not Yet Recruiting
  • Local Institution - 0020
    White Plains, New York
    Site status: Not Yet Recruiting
  • Magnolia Clinical Research, LLC
    Cary, North Carolina
    Site status: Recruiting
  • PPD Virtual - PPD - US
    Wilmington, North Carolina
    Site status: Recruiting
  • Local Institution - 0031
    Mason, Ohio
    Site status: Not Yet Recruiting
  • The Rivus Wellness & Research Institute
    Oklahoma City, Oklahoma
    Site status: Recruiting
  • Local Institution - 0052
    Tulsa, Oklahoma
    Site status: Not Yet Recruiting
  • Perelman School of Medicine at the University of Pennsylvania
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Local Institution - 0053
    State College, Pennsylvania
    Site status: Not Yet Recruiting
  • Local Institution - 0051
    Cordova, Tennessee
    Site status: Not Yet Recruiting
  • Psychiatric Consultants, Pc
    Franklin, Tennessee
    Site status: Recruiting
  • Local Institution - 0016
    Austin, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0050
    Dallas, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0021
    Fort Worth, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0033
    Houston, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0026
    Houston, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0022
    Houston, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0010
    Houston, Texas
    Site status: Not Yet Recruiting
  • Pioneer Research Solutions, Inc.
    Houston, Texas
    Site status: Recruiting
  • Local Institution - 0017
    Irving, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0013
    McKinney, Texas
    Site status: Not Yet Recruiting
  • Perceptive Pharma Research
    Richmond, Texas
    Site status: Recruiting
  • UT Health San Antonio - Behavioral Health and Wellness Center
    San Antonio, Texas
    Site status: Recruiting
  • Local Institution - 0018
    Stafford, Texas
    Site status: Not Yet Recruiting
  • Local Institution - 0045
    Petersburg, Virginia
    Site status: Not Yet Recruiting
In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with schizophrenia. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Xanomeline and trospium chloride (KarXT). The phase is not clearly listed in the public registry. Phase is mostly relevant for medication studies and some device studies. For this study, it may be more useful to look at what is required, the duration, visits, and eligibility criteria.

Who might this study be for?

This study may concern people with schizophrenia; age range: Over 18 Years. The criteria appear fairly broad, but you should not assume you are eligible. The study team must confirm diagnosis, age, exclusions, available locations, and next steps.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Bristol-Myers Squibb, which appears to be a pharmaceutical company. Sponsor website: https://www.bms.com. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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