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RecruitingNCT07420283

Brenipatide for Addiction

The registry lists this study as recruiting. Study locations are listed in the United States, in Canada, and in the United Kingdom. Confirm recruitment at each site. It is testing brenipatide for Addiction.

AddictionDrugFrom 18 Years to 75 Years
In plain English

Key information made simple

What is this study testing?

This study is testing whether Brenipatide may be useful for adults experiencing addiction.

What would participation involve?

Participants may receive Brenipatide, attend study visits with the research team. The protocol may also involve randomization, placebo, or a comparison group. The registry lists locations in Canada, in the United States, and in the United Kingdom.

Who is it mainly for?

This study appears to be mainly for adults with addiction.

What should you check before joining?

Ask about the dose, safety monitoring, and possible side effects, whether there is placebo, randomization, or a comparison group, how many visits or travel steps are needed, the exact eligibility criteria.

Your next step

Check the study details

Check the official source, then confirm these points with the research team.

View official study record (opens in a new tab)
  • Recruitment and eligibility

    Is a site open, and who can take part?

  • Visits and time

    Where are visits, can any be remote, and how much time is needed?

  • Costs and support

    What costs, reimbursement or compensation apply?

Before joining

Questions to ask before joining

Study clarity

Things to check before joining

Study start dateStarted: February 13, 2026
Recruitment status
Recruiting
Enrollment listed in the registry
465
Sponsor
Eli Lilly and Company
Sponsor type
Other organization
Study type
Drug
Intervention type
Medication / drug
Study phase
Phase 2Usually explores whether the intervention may work, while continuing to monitor safety.
Locations
United States, Canada, United Kingdom
Age range
From 18 Years to 75 Years
Official registry ID
NCT07420283
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study With a Separate Open-label Cohort to Evaluate the Efficacy and Safety of Brenipatide as Adjunctive Treatment to Transmucosal Buprenorphine With or Without Naloxone in Early Recovery of Participants With Opioid Use Disorder (RENEW-Op-1)

Check recruitment and locations

Recruitment checked against the registry by HopeStage on . Registry information can change. Always confirm availability with the research team.

View official study record (opens in a new tab)

The overall study status can differ from each site's status. Open a country to see its locations and their registry status.

Canada · 8 sites
  • CaRe Clinic
    Calgary
    Site status: Recruiting
  • Med Trust Research
    Courtice
    Site status: Recruiting
  • The Medical Arts Health Research Group
    Kamloops
    Site status: Recruiting
  • Kelowna Health and Memory Centre
    Kelowna
    Site status: Recruiting
  • Providence Care
    Kingston
    Site status: Recruiting
  • Malton Medical Group
    Mississauga
    Site status: Recruiting
  • Comprehensive Treatment Clinic
    Toronto
    Site status: Recruiting
  • Centre for Addiction and Mental Health (CAMH)
    Toronto
    Site status: Recruiting
Puerto Rico · 1 site
  • Research Works San Juan
    Guaynabo
    Site status: Recruiting
United Kingdom · 12 sites
  • Surrey and Borders Partnership NHS Foundation Trust
    Chertsey
    Site status: Recruiting
  • Clerkenwell Health - Doncaster
    Doncaster
    Site status: Not Yet Recruiting
  • St Pancras Clinical Research - Eastbourne
    Eastbourne
    Site status: Not Yet Recruiting
  • Queen Elizabeth University Hospital
    Glasgow
    Site status: Recruiting
  • St Pancras Clinical Research
    London
    Site status: Recruiting
  • Bioluminux - London
    London
    Site status: Recruiting
  • Clerkenwell Health - London - Welbeck Street
    London
    Site status: Not Yet Recruiting
  • Greater Manchester Mental Health NHS Foundation Trust
    Manchester
    Site status: Not Yet Recruiting
  • Bioluminux Clinical Research - Milton Keynes
    Milton Keynes
    Site status: Recruiting
  • Bioluminux - Southampton
    Southampton
    Site status: Recruiting
  • Old Bank House Hillingdon Drug & Alcohol
    Uxbridge
    Site status: Not Yet Recruiting
  • Bioluminux - Wolverhampton
    Wolverhampton
    Site status: Recruiting
United States · 38 sites
  • NoesisPharma - Phoenix - East Shea Boulevard
    Phoenix, Arizona
    Site status: Recruiting
  • Pillar Clinical Research- Little Rock
    Little Rock, Arkansas
    Site status: Recruiting
  • Woodland International Research Group
    Little Rock, Arkansas
    Site status: Recruiting
  • Ark Clinical Research - Fountain Valley
    Fountain Valley, California
    Site status: Recruiting
  • Center on Substance Use and Health (CSUH)
    San Francisco, California
    Site status: Recruiting
  • UCSF Weill Institute for Neurosciences - Substance Use Disorders Clinic - Mission Bay
    San Francisco, California
    Site status: Recruiting
  • Bradenton Research Center, Inc.
    Bradenton, Florida
    Site status: Recruiting
  • K2 Medical Research - Daytona Beach
    Daytona Beach, Florida
    Site status: Recruiting
  • NextPhase Research Florida - Hollywood
    Hollywood, Florida
    Site status: Recruiting
  • Accel Research Sites - Lakeland Clinical Research Unit
    Lakeland, Florida
    Site status: Recruiting
  • Life Arc Research Centers - Miami
    Miami, Florida
    Site status: Recruiting
  • Advanced Research for Health Improvement, LLC
    Naples, Florida
    Site status: Recruiting
  • Innovative Research Institute - Port Charlotte
    Port Charlotte, Florida
    Site status: Recruiting
  • Better Years Ahead Medical Center
    Tampa, Florida
    Site status: Recruiting
  • Neuroscience Research Institute - West Palm Beach
    West Palm Beach, Florida
    Site status: Recruiting
  • Re:Cognition Health - Chicago
    Chicago, Illinois
    Site status: Recruiting
  • Indiana University Health Neuroscience Center
    Indianapolis, Indiana
    Site status: Recruiting
  • University of Kentucky Chandler Medical Center
    Lexington, Kentucky
    Site status: Recruiting
  • Maryland Treatment Centers - Mountain Manor Treatment Center
    Baltimore, Maryland
    Site status: Recruiting
  • Maryland Treatment Centers - Avery Road Treatment Center
    Rockville, Maryland
    Site status: Recruiting
  • Brigham and Women's Hospital
    Boston, Massachusetts
    Site status: Recruiting
  • Adams Clinical Boston
    Boston, Massachusetts
    Site status: Recruiting
  • Boston Medical Center
    Boston, Massachusetts
    Site status: Not Yet Recruiting
  • Adams Clinical Watertown
    Watertown, Massachusetts
    Site status: Recruiting
  • SKY Integrative Medical Center/SKYCRNG
    Ridgeland, Mississippi
    Site status: Recruiting
  • Adams Clinical Harlem
    New York, New York
    Site status: Recruiting
  • Adams Clinical Bronx
    The Bronx, New York
    Site status: Recruiting
  • Ohio Clinical Trials
    Columbus, Ohio
    Site status: Recruiting
  • Rivus Wellness and Research Institute
    Oklahoma City, Oklahoma
    Site status: Not Yet Recruiting
  • Adams Clinical Philadelphia
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Penn Medicine: University of Pennsylvania Health System
    Philadelphia, Pennsylvania
    Site status: Recruiting
  • Brown University School of Public Health
    Providence, Rhode Island
    Site status: Recruiting
  • Avera Research Institute - Sioux Falls
    Sioux Falls, South Dakota
    Site status: Recruiting
  • Adams Clinical Dallas
    DeSoto, Texas
    Site status: Recruiting
  • Biopharma Informatic, LLC
    Houston, Texas
    Site status: Recruiting
  • University of Virginia Health System
    Charlottesville, Virginia
    Site status: Not Yet Recruiting
  • Carilion Clinic
    Roanoke, Virginia
    Site status: Recruiting
  • University of Washington - Harborview Medical Center
    Seattle, Washington
    Site status: Recruiting

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In practice

For you

Participation may contribute to research. Personal benefit is not guaranteed.

Ask the research team to explain the activities, time commitment, and follow-up involved.

Study sites are listed. Confirm the relevant site and any travel before making plans.

Important

Not medical advice

Information from public sources. Are you the study sponsor? Contact us to update this page: hi@hopestage.com

FAQ

Questions about this study

What is this study trying to understand?

This study is exploring medication or study treatment for people with addiction. Participants may complete study visits, assessments, or follow-up activities defined by the research team. Direct benefit is not guaranteed. The detailed objective is not always clearly listed in the public registry; the study team can confirm.

Does this study involve a medication?

This appears to be a medication / drug study involving Brenipatide, Placebo, Buprenorphine. Phase 2 studies usually explore whether the intervention may work, while continuing to monitor safety.

Are there criteria about substance use or wanting to reduce it?

The public registry appears to mention tobacco, nicotine, alcohol, cannabis, or another addiction-related topic. Ask the study team whether you need to want to stop, reduce, already be abstinent, or simply meet use-related criteria. Eligibility must be confirmed by the study team.

What would I likely need to do?

You may need to take a study treatment and have regular medical follow-up. The listed study locations suggest that at least part of participation may involve a physical site. Ask whether some steps can be done remotely.

What side effects, interactions, or treatment changes should I check?

If the study involves a medication, ask whether it is already approved, experimental, or being tested for a new use. Check possible side effects, interactions with current treatment, dose changes, monitoring, and what happens if you feel worse. For any mental health study, also ask who to contact if you feel worse, whether participation may affect current treatment, whether you can stop, and who confirms eligibility.

Will I need to travel or attend in-person visits?

The listed study locations suggest that at least part of participation may involve a physical site. Ask which sites are open, how many visits are expected, whether any steps can be done remotely, and whether travel costs or compensation are listed.

Who is behind this study?

This study is sponsored by Eli Lilly and Company, which appears to be another type of organization. If available, it can be useful to check the sponsor website, collaborators, investigator affiliation, and the official registry before deciding. HopeStage does not judge the quality of a sponsor or researcher, but helps you identify what to verify.

Can I still join this study?

The public registry lists this study as recruiting. Individual sites may have different statuses. The research team must confirm whether a site is open and whether you meet the criteria.

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