RecruitingNCT07487818
Vagus nerve stimulation with nicotine replacement to support smoking cessation
About this title
Read the official source — NCT07487818Medication studyAges 18+United StatesAddiction
Understand this study
Who could participate?
Listed age limits: from 18 years.
What will I do during this study?
Participants are randomly assigned to nicotine patches plus brief behavioural support, either with or without a handheld vagal nerve stimulation device. The first phase lasts 12 weeks: the device is placed on the neck for two minutes per treatment, up to 30 stimulations over 24 hours. The record describes a further 12-week varenicline retreatment phase for participants who are still smoking; others who are smoke-free move to follow-up without medication.
- Listed locations
- RochesterSee all locations and recruitment
- Study phase
- Phase 2 / Phase 3This study spans more than one phase, so it may combine goals such as safety, dosing, and early effectiveness.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: June 4, 2026
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 150
- Sponsor
- Mayo Clinic
- Sponsor type
- Hospital / academic medical center
- Study type
- Drug
- Intervention type
- COMBINATION_PRODUCT, Medication / drug
- Study phase
- Phase 2 / Phase 3This study spans more than one phase, so it may combine goals such as safety, dosing, and early effectiveness.
- Locations
- United States
- Age range
- Over 18 Years
- Official registry ID
- NCT07487818
- Official title
Show the full official title
Using Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Rochester
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is Mayo Clinic, a hospital or academic medical center.
Does this study involve medication?
Yes. The study involves medication, including nicotine replacement patches.
Who can participate?
Listed age limits: from 18 years.
Is this study still recruiting?
The registry lists this study as recruiting.
