RecruitingNCT07644052
PP-01, nabilone, or placebo for cannabis withdrawal
About this title
Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder
Read the official source — NCT07644052Medication studyAges 18–55United StatesAddiction
Understand this study
Who could participate?
Listed age limits: 18 years to 55 years.
What will I do during this study?
Depending on your group, you take PP-01, nabilone or placebo (an inactive comparison treatment) daily for 34 days. After an initial inpatient period, the protocol includes six clinic visits and two telemedicine appointments. You also complete daily symptom diaries and study questionnaires; any later repeat-dosing extension has separate eligibility criteria.
- Listed locations
- Little Rock and 21 more locationsSee all locations and recruitment
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
What to know before participating
A point to clarify
This summary does not cover all risks or eligibility requirements. What risks or changes to my care would apply to me?
Things to check before joining
Study start dateStarted: June 17, 2026
- Recruitment status
- Recruiting
- Enrollment listed in the registry
- 420
- Sponsor
- PleoPharma, Inc.
- Sponsor type
- Other organization
- Study type
- Drug
- Intervention type
- COMBINATION_PRODUCT, Medication / drug
- Study phase
- Phase 3Usually a larger study designed to confirm effectiveness and safety in a broader group.
- Locations
- United States
- Age range
- From 18 Years to 55 Years
- Official registry ID
- NCT07644052
- Official title
Show the full official title
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo and Active-Controlled Clinical Trial of Titrating Doses of PP-01 for the Mitigation of Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder: Core Study With Safety Extension Phase
Recruitment & locations
Currently recruitingA study may be recruiting, but some locations may no longer be accepting participants. Confirm availability with the research team.
Little Rock · Rogers · New Haven
19 more locations
- DeLand
- Hollywood
- Largo
- Tampa
- West Palm Beach
- Decatur
- Norcross
- Savannah
- Lexington
- Baltimore
- Las Vegas
- Marlton
- New York
- Staten Island
- North Canton
- North Charleston
- Knoxville
- Austin
- Houston
Interested in joining this study?
Questions about this study
Who is behind this study?
The study sponsor is PleoPharma, Inc.
Does this study involve medication?
Yes. The study involves medication, including Nabilone and Placebo.
Who can participate?
Listed age limits: 18 years to 55 years.
Is this study still recruiting?
The registry lists this study as recruiting.
