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Bipolarity studies

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Recruiting now refers to the overall study. Local openings are shown only when the registry lists an open site.

Bipolarity

Bipolarity involves episodes of depression and periods of elevated or irritable mood, with unusually high energy and activity.

27studies shown
Showing 1-12 of 27
Drug study icon
RecruitingNCT07140913

KarXT with lithium, valproate, or lamotrigine for mania in bipolarity

About this title

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

Read the official source — NCT07140913
What is this study about?

Researchers compare KarXT with placebo, each added to lithium, valproate or lamotrigine, in people with bipolarity type I experiencing mania, with or without mixed features. They want to know whether adding KarXT improves manic symptoms and assess its safety.

Recruiting in France
BipolarityMedication studyAges 18–65
Countries
France, United States, Argentina, + 10 others
Sponsor
Bristol-Myers Squibb (Pharmaceutical company)
Drug study icon
RecruitingNCT06929273

Long-term safety of KarXT in bipolarity type I

What is this study about?

This extension study evaluates the long-term safety and tolerability of KarXT for mania or mania with mixed features in people living with bipolarity type I.

Recruiting in France
BipolarityMedicationAges 18–65
Countries
France, United States, Australia, + 17 others
Sponsor
Bristol-Myers Squibb (Pharmaceutical company)
Device study icon
RecruitingNCT07194278

Feasibility of blue-blocking glasses during mania in bipolarity

About this titleRead the official source — NCT07194278
What is this study about?

Researchers are testing whether a study of blue-light-blocking glasses is practical and acceptable for adults hospitalized with mania and bipolarity type I. Participants wear the glasses while researchers assess manic symptoms, sleep and how well the study procedures work.

Recruiting in France
BipolarityDevice studyAges 18+
Countries
France
Sponsor
Centre Hospitalier St Anne
Other study type icon
RecruitingNCT05878730

Melatonin patterns in people with bipolarity who respond or do not respond to lithium

About this titleRead the official source — NCT05878730
What is this study about?

Researchers compare overnight melatonin-related urine measurements in people with bipolarity type I who respond well or poorly to lithium, while their mood is stable. They want to understand whether body-clock biology helps explain differences in lithium response; melatonin is being measured, not given as treatment.

Recruiting in France
BipolarityObservational studyAges 18–70
Countries
France
Sponsor
Assistance Publique - Hôpitaux de Paris
Behavioral study icon
RecruitingNCT04184375

Cognitive Stimulation for Elderly Bipolar Patients

Official study title

Evaluation of Cognitive Stimulation on Dysexecutive Residual Symptoms in Bipolar Patients Over 65 Years of Age

Recruiting in France
BipolarityBehavioural studyAges 65+
Countries
France
Sponsor
Groupe Hospitalier de la Rochelle Ré Aunis
Behavioral study icon
RecruitingNCT04432116

Time perception and virtual reality in schizophrenia and bipolarity

About this title

Time and Virtual Reality in Schizophrenia and Bipolar Disorder

Read the official source — NCT04432116
Official study title

EEG and Behavioural Correlates of Virtual Reality Treatment of Environmental Zeitgebers in Schizophrenia and Bipolar Disorder

Recruiting in France
Bipolarity, SchizophreniaBehavioural studyAges 18–60
Countries
France
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Other study type icon
RecruitingNCT07031817

Blood markers and a questionnaire to assess bipolarity

About this title

Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Disorder

Read the official source — NCT07031817
Official study title

Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Disorder in Patients With a Characterized Depressive Episode in Primary Care

Recruiting in France
Bipolarity, DepressionStudy assessmentsAges 18–65
Countries
France
Sponsor
University Hospital, Montpellier

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.