Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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1394studies shown
Showing 376-400 of 1,394
RecruitingISRCTN97160532

SMRI-02T-162A: double blind placebo controlled trial of a protein kinase C inhibitor: tamoxifen citrate in treatment of acute mania

This study is looking at whether a digital support tool can help people with bipolarity-I, most recent episode manic or mixed, with or without psychotic features, Mental and Behavioural Disorders, or bipolarity. Participants receive a study treatment and complete follow-up visits and assessments.

BipolarityOtherOver 18 Years
Countries
Turkey, United States
Sponsor
The Stanley Medical Research Institute (SMRI) (USA)
Condition
Bipolarity
RecruitingISRCTN55261332

Bipolarity: Lithium/ANti-Convulsant Evaluation

This study is looking at whether 1 can help people with bipolarity or Mental and Behavioural Disorders. Participants take part in 1 and complete follow-up assessments.

BipolarityOther
Countries
United Kingdom, France, Germany, Ireland, Italy, United States
Sponsor
University of Oxford (UK)
Condition
Bipolarity
RecruitingISRCTN41352631

Feasability study of Enhanced Relapse Prevention (ERP) delivered by Care Coordinators (CCs) to people with Bipolarity (BD) - a cluster randomised controlled trial

This study is looking at care and outcomes for people with bipolarity or Mental and Behavioural Disorders. Taking part may give some people access to a digital support tool, but direct benefit is not guaranteed.

BipolarityOther
Countries
United Kingdom
Sponsor
The University of Liverpool (UK)
Condition
Bipolarity
RecruitingISRCTN36852818

Psychoeducation versus cognitive-behavioral therapy in bipolarity

This study is looking at whether cognitive behavioural therapy can help people with bipolarity or Mental and Behavioural Disorders. Participants take part in cognitive behavioural therapy and complete follow-up assessments.

BipolarityOtherOver 18 Years
Countries
Canada
Sponsor
University of Toronto (Canada)
Condition
Bipolarity
RecruitingISRCTN27649427

Efficacy of mifepristone in the treatment of Depression in bipolarity

This study is looking at care and outcomes for people with Depression in bipolarity or Mental and Behavioural Disorders. Taking part may give some people access to Adjunctive treatment with mifepristone (600 mg/day for 7 days) versus placebo, but direct benefit is not guaranteed.

DepressionOtherFrom 18 Years to 65 Years
Countries
United Kingdom
Sponsor
The Newcastle, North Tyneside And Northumberland Mental Health NHS Trust (UK)
Condition
Depression
RecruitingISRCTN28588282

Efficacy and safety of agomelatine given orally compared to placebo, in addition to a mood stabiliser in bipolar I patients with a current major depressive episode. An eight week randomised, double-blind, controlled, parallel group study followed by a double-blind extension treatment period up to one year

This study is looking at care and outcomes for people with Major depressive episode, Mental and Behavioural Disorders, or Depression. Some participants may receive placebo instead of the study treatment, and direct benefit is not guaranteed.

DepressionOtherOver 18 Years
Countries
France
Sponsor
Institut de Recherches Internationales Servier (France)
Condition
Depression
RecruitingISRCTN21277091

Randomised controlled trial of efficacy of teaching patients with bipolarity to identify early symptoms of relapse and obtain treatment

This study is looking at how 7 - 12 intervention treatment sessions from a research psychologist plus routine care versus routine care only works for people with Schizophrenia and other psychoses, Mental and Behavioural Disorders, or Schizophrenia in routine care. Participants take part in 7 - 12 intervention treatment sessions from a research psychologist plus routine care versus routine care only and complete follow-up assessments.

SchizophreniaOtherOver 18 Years
Countries
United Kingdom
Sponsor
NHS R&D Regional Programme Register - Department of Health (UK)
Condition
Schizophrenia
OngoingEUCTR 2014-003803-31

Adjunct pioglitazone IN THE TREATMENT OF Bipolarity.

This study is comparing PIOGLITAZONE with placebo for people with bipolarity. Participants receive PIOGLITAZONE or placebo and complete study visits and assessments.

BipolarityOther
Countries
Spain
Sponsor
Hospital Universitario Araba (Sede Santiago)
Condition
Bipolarity
OngoingEUCTR 2008-004746-81

Effect of amiloride on lithium-induced chronic nephropathy. Comparing discontinuation of lithium treatment to adding amiloride while continuing lithium treatment.

This study is looking at whether AMILORIDE (Modamide) can help people with Renal failure due to long-term use of lithium salts in with bipolarity or Elderly. Participants receive the study medicine AMILORIDE (Modamide) and complete study visits and assessments.

BipolarityOther
Countries
Netherlands
Sponsor
Parnassia-BAVO groep [...] 1. Parnassia-BAVO groep 2. St. Elisabeth Ziekenhuis 3. University Medical Center Utrecht
Condition
Bipolarity
OngoingEUCTR 2018-002263-26

Optimizing response to Li treatment through personalized evaluation of individuals with Bipolarity type I

This study is looking at whether Lithionit can help people with individuals with bipolar I disorders who initiate lithium treatment based on the decision of themselves and their clinician or Elderly. Participants receive the study medicine Lithionit and complete study visits and assessments.

BipolarityOther
Countries
Norway, Sweden, Germany, Denmark, Spain, Italy
Sponsor
DRCI APHP
Condition
Bipolarity
OngoingEUCTR 2011-003190-29

Optimizing Antidepressant Treatment by Genotype-dependent Adjustment of Medication according to the the ABCB1 Gene

This study is looking at whether PAROXETINE compared with SERTRALINE HYDROCHLORIDE can help people with Major Depression, single or recurrent, without psychotic features - bipolarity, currently depressed, without psychotic features or Elderly. Participants receive one of the study medicines, such as PAROXETINE or SERTRALINE HYDROCHLORIDE, and complete study visits and assessments.

SchizophreniaOther
Countries
Germany
Sponsor
HolsboerMaschmeyer NeuroChemie (HMNC) GmbH
Condition
Schizophrenia
OngoingEUCTR 2019-002213-19

A 6-Week Randomised, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy of Lurasidone Adjunctive Therapy in Improving Cognitive Functioning in Euthymic Bipolarity Pa...

This study is comparing Lurasidone Hydrochloride with placebo for people with Euthymic bipolarity or Elderly. Participants receive Lurasidone Hydrochloride or placebo and complete study visits and assessments.

BipolarityOther
Countries
United Kingdom
Sponsor
University of British Columbia
Condition
Bipolarity
OngoingEUCTR 2004-001308-11

Optimal Treatment Duration with Olanzapine following Remission of Manic or Mixed Episode. An Open-Label, Randomized Trial Comparing Two Treatment Strategies

This study is looking at whether OLANZAPINA can help people with to compare the efficacy in the prevention of relapse to manic, depressive, or mixed episodes in two groups of bipolar I or Elderly. Participants receive the study medicine OLANZAPINA and complete study visits and assessments.

BipolarityOther
Countries
Spain
Sponsor
Lilly.S.A.
Condition
Bipolarity
OngoingEUCTR 2007-000479-40

Effects of quetiapine on ultrastructural hippocampal and neurochemical changes in patients with bipolarity: searching for the antidepressant and mood stabilising neurophysiology

This study is looking at whether Quetiapine can help people with bipolarity is a common mental health conditions which is characterised by manic and depressive states. The mood stabilizing effect of novel antipsychotics seems to be modulation of neuronal plast.

BipolarityOther
Countries
Germany
Sponsor
Department of Psychiatry, RWTH Aachen
Condition
Bipolarity