Get research updatesBipolarity involves episodes of depression and periods of elevated or irritable mood, with unusually high energy and activity.
Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression
Read the official source — NCT07127913Closed-Loop Deep Brain Stimulation for Bipolar Depression (PReSiDio-BP)
Building Mood State Classifiers to Inform Deep Brain Stimulation of Treatment-Resistant Bipolar Depression
A Randomized, Double-blind, Placebo-controlled Study to Determine Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
Read the official source — NCT06088732Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
Read the official source — NCT06221852Researchers compare a ketogenic diet with a diet based on standard American dietary guidance, alongside usual care, after a first episode of bipolarity or schizoaffective illness. Brain imaging and metabolic measurements help assess changes in brain energy use and psychiatric symptoms.
Ketogenic Intervention for Bipolar Depression
Read the official source — NCT07121894This study assesses depression symptoms.
Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
Read the official source — NCT05648591Open-label Safety Study of a 1-year 8 to 24 mg/Day Dose Regimen of Iloperidone (FANAPT®) in Adolescent Patients With Schizophrenia or Bipolar I Disorder
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Read the official source — NCT06229210An Open-label, Multicenter Trial to Assess the Safety and Tolerability of Lumateperone in the Treatment of Pediatric Patients With Schizophrenia, Bipolar Disorder, or Autism Spectrum Disorder
Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder
Read the official source — NCT06740331Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
Read the official source — NCT05303064A Phase 3, Randomized, Double-Blind, 52-Week Study of OLZ/SAM vs Olanzapine to Evaluate Weight Gain as Assessed by Change in BMI Z-Score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder (ENLIGHTEN-Youth)
TIDE (Trimetazidine in bipolar depression): A double-blind, randomised, placebo-controlled trial to evaluate the effect of trimetazidine on depressive symptoms in patients with bipolar disorder
We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.