Study directory

Mental health studies with practical context.

Public study records, presented in a clearer and more patient-friendly format for mental health research discovery.

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1394studies shown
Showing 401-425 of 1,394
OngoingEUCTR 2015-000323-86

A randomised, parallel group, double blind, placebo controlled, add on clinical trial to investigate whether the lithium mimetic, ebselen, can reduce symptoms of hypomania and mania in bipolar pati...

This study is comparing SPI-1005, ebselen with placebo for people with with bipolarity meeting DSM-5 criteria for hypomania or mania or Elderly. Participants receive SPI-1005, ebselen or placebo and complete study visits and assessments.

BipolarityOther
Countries
United Kingdom
Sponsor
University of Oxford
Condition
Bipolarity
CompletedEUCTR 2017-000497-11

A Study to Evaluate the Effect of ALKS 3831 Compared to Olanzapine on Body Weight in Young Adults with Schizophrenia, Schizophreniform, or Bipolarity I Who are Early in Their Illness

This study is comparing Samidorphan L-Malate with OLANZAPINE for people with Schizophrenia, schizophreniform disorder or Bipolarity type I. Participants receive Samidorphan L-Malate or OLANZAPINE and complete study visits and assessments.

SchizophreniaOther
Countries
Austria, Germany, Spain, Italy, Romania, View results
Sponsor
Alkermes Inc
Condition
Schizophrenia
Not Yet RecruitingNCT07556861

A Study Of Senyo Health With Comorbid Alcohol Use Disorder Treatment In Bipolar Patients

This study is testing a telehealth collaborative care platform for people living with bipolarity and alcohol use difficulties. Participants use the Senyo Health support approach and complete follow-up assessments to see whether it improves retention and substance use outcomes.

BipolarityOtherOver 18 Years
Countries
United States
Sponsor
Mayo Clinic
Condition
Bipolarity
CompletedNCT07549581

A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode

This study assessed the safety and pharmacology of SEP-380135 in adults living with schizophrenia or a major depressive episode linked to bipolarity or major depressive disorder. The registry now lists the study as completed.

DepressionOtherFrom 18 Years to 55 Years
Countries
United States
Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Condition
Depression
CompletedNCT06419582

BHV-7000 Acute Treatment of Bipolar Mania

This study tested BHV-7000 as an acute treatment for manic episodes in bipolarity. The public registry page now lists the trial as completed.

BipolarityOtherFrom 18 Years to 75 Years
Countries
United States
Sponsor
Biohaven Therapeutics Ltd.
Condition
Bipolarity
OngoingEUCTR 2021-004049-19

Sodium oxybate as a potential new treatment for catatonia in patients with depression, bipolarity or a psychotic disorder, a randomized controlled trial. The Laborit study.

This EU CTR study is testing sodium oxybate for catatonia in adults living with depression, bipolarity, or psychotic disorders. The registry page currently marks the Dutch protocol as transitioned, which the app maps to ongoing.

DepressionOther
Countries
Netherlands
Sponsor
Amsterdam UMC
Condition
Depression
CompletedNCT06605599

Study of Oral ABBV-932 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Bipolar I or II Disorder

This completed Phase 2 study tested whether the oral investigational medication ABBV-932 was safe and could improve depressive episodes in adults living with bipolarity type I or II. Participants were assigned to one of three ABBV-932 dose groups or to placebo, took capsules once daily for 6 weeks, and then had a 4-week safety follow-up.

BipolarityOtherFrom 18 Years to 65 Years
Countries
Japan, United States
Sponsor
AbbVie
Condition
Bipolarity
CompletedNCT06273774

A Study of Elpipodect (MK-8189) in Participants With Bipolarity I (MK-8189-020)

This study exists to better understand the safety of the medication Elpipodect and how manageable it feels in practice. For people living with Bipolarity, that matters because care needs to work in daily life, not just in theory.

BipolarityOtherFrom 18 Years to 60 Years
Countries
United States
Sponsor
Merck Sharp & Dohme LLC
Condition
Bipolarity
CompletedNCT07548359

Psychiatric Nursing Intervention for Caregivers of Patients With Bipolarity

This study exists to explore whether psychoeducation, a guided learning and support program, could improve care and understanding. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can give earlier or clearer feedback during care.

BipolarityOtherOver 18 Years
Countries
Egypt
Sponsor
Menoufia University
Condition
Bipolarity
Active Not RecruitingNCT05054699

Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study

This study exists to compare options and see whether a therapy or guided support program offers something meaningfully different. Researchers are trying to understand whether a therapy or guided support program can improve attention, thinking, or day-to-day functioning.

DepressionOtherFrom 18 Years to 65 Years
Countries
Brazil
Sponsor
University of Sao Paulo
Condition
Depression
Not Yet RecruitingNCT07534475

Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT

This study exists to see whether a therapy or guided support program can make care clearer and more responsive. Researchers are trying to understand whether a therapy or guided support program can give earlier or clearer feedback during care.

DepressionOtherFrom 18 Years to 65 Years
Countries
Turkey
Sponsor
Medipol University
Condition
Depression
RecruitingNCT07540338

A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolarity I

This study exists to compare options and see whether blood tests and biological markers offers something meaningfully different. Researchers are trying to understand how people respond to blood tests and biological markers in practice and what may need to be adjusted.

BipolarityOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
Alzamend Neuro, Inc.
Condition
Bipolarity
Not Yet RecruitingNCT07506070

Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital

This study exists to see whether a therapy or guided support program is workable and worth testing more broadly. Researchers are trying to understand whether a therapy or guided support program can improve attention, thinking, or day-to-day functioning.

DepressionOtherFrom 18 Years to 60 Years
Countries
Global
Sponsor
The Royal Ottawa Mental Health Centre
Condition
Depression
CompletedNCT05317481

Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms

This study exists to understand how psychoeducation, a guided learning and support program, holds up over time after the earliest research stage. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can improve sleep, daily rhythms, and longer-term stability.

DepressionOtherFrom 16 Years to 29 Years
Countries
United States
Sponsor
Yale University
Condition
Depression
Active Not RecruitingNCT03349528

Probiotics to Prevent Relapse After Hospitalization for Depression in bipolarity

This study exists to compare options and see whether this type of care offers something meaningfully different. Researchers are trying to understand whether this type of care can better prevent setbacks and support longer-term stability.

DepressionOtherFrom 18 Years to 65 Years
Countries
United States
Sponsor
Sheppard Pratt Health System
Condition
Depression
CompletedNCT01470781

Treatment to Enhance Cognition in Bipolarity

This study exists to compare options and see whether brain scans or other body measurements offers something meaningfully different. Researchers are trying to understand whether brain scans or other body measurements can improve attention, thinking, or day-to-day functioning.

BipolarityOtherFrom 18 Years to 50 Years
Countries
United States
Sponsor
Mclean Hospital
Condition
Bipolarity
Not Yet RecruitingNCT07510646

Transcranial Photobiomodulation for Depression in bipolarity

This study exists to see whether a therapy or guided support program can play a useful role in care. Researchers are trying to understand whether a therapy or guided support program can better support energy, concentration, and everyday functioning.

DepressionOtherOver 18 Years
Countries
Canada
Sponsor
Vielight Inc.
Condition
Depression
TerminatedNCT05724953

Alexithymia Intervention for Suicide

This study exists to see whether psychoeducation, a guided learning and support program, is workable and worth testing more broadly. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can make support easier to access outside standard clinic visits.

DepressionOtherOver 18 Years
Countries
United States
Sponsor
VA Office of Research and Development
Condition
Depression
CompletedNCT04298450

ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention

This study exists to see whether psychoeducation, a guided learning and support program, can play a useful role in care. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can work better when mental health difficulties overlap with substance use.

SchizophreniaOtherFrom 16 Years to 29 Years
Countries
Canada
Sponsor
Centre for Addiction and Mental Health
Condition
Schizophrenia