OngoingEUCTR 2015-000323-86
This study is comparing SPI-1005, ebselen with placebo for people with with bipolarity meeting DSM-5 criteria for hypomania or mania or Elderly. Participants receive SPI-1005, ebselen or placebo and complete study visits and assessments.
BipolarityOther
- Countries
- United Kingdom
- Sponsor
- University of Oxford
- Condition
- Bipolarity
CompletedEUCTR 2017-000497-11
This study is comparing Samidorphan L-Malate with OLANZAPINE for people with Schizophrenia, schizophreniform disorder or Bipolarity type I. Participants receive Samidorphan L-Malate or OLANZAPINE and complete study visits and assessments.
SchizophreniaOther
- Countries
- Austria, Germany, Spain, Italy, Romania, View results
- Sponsor
- Alkermes Inc
- Condition
- Schizophrenia
Not Yet RecruitingNCT07556861
This study is testing a telehealth collaborative care platform for people living with bipolarity and alcohol use difficulties. Participants use the Senyo Health support approach and complete follow-up assessments to see whether it improves retention and substance use outcomes.
BipolarityOtherOver 18 Years
- Countries
- United States
- Sponsor
- Mayo Clinic
- Condition
- Bipolarity
CompletedNCT07549581
This study assessed the safety and pharmacology of SEP-380135 in adults living with schizophrenia or a major depressive episode linked to bipolarity or major depressive disorder. The registry now lists the study as completed.
DepressionOtherFrom 18 Years to 55 Years
- Countries
- United States
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Condition
- Depression
CompletedNCT06419582
This study tested BHV-7000 as an acute treatment for manic episodes in bipolarity. The public registry page now lists the trial as completed.
BipolarityOtherFrom 18 Years to 75 Years
- Countries
- United States
- Sponsor
- Biohaven Therapeutics Ltd.
- Condition
- Bipolarity
OngoingEUCTR 2021-004049-19
This EU CTR study is testing sodium oxybate for catatonia in adults living with depression, bipolarity, or psychotic disorders. The registry page currently marks the Dutch protocol as transitioned, which the app maps to ongoing.
DepressionOther
- Countries
- Netherlands
- Sponsor
- Amsterdam UMC
- Condition
- Depression
OngoingEUCTR 2021-001337-40
This EU CTR study is evaluating BXCL501 for agitation linked to pediatric schizophrenia and bipolarity. The Spanish protocol is listed as restarted, which the app currently maps to ongoing.
SchizophreniaOther
- Countries
- Spain
- Sponsor
- BioXcel Therapeutics, Inc.
- Condition
- Schizophrenia
CompletedNCT06605599
This completed Phase 2 study tested whether the oral investigational medication ABBV-932 was safe and could improve depressive episodes in adults living with bipolarity type I or II. Participants were assigned to one of three ABBV-932 dose groups or to placebo, took capsules once daily for 6 weeks, and then had a 4-week safety follow-up.
BipolarityOtherFrom 18 Years to 65 Years
- Countries
- Japan, United States
- Sponsor
- AbbVie
- Condition
- Bipolarity
CompletedNCT04684615
This study exists to see whether the medication COVID-19 can make care clearer and more responsive. Researchers are trying to understand whether the medication COVID-19 can give earlier or clearer feedback during care.
BipolarityOtherOver 18 Years
- Countries
- United States
- Sponsor
- National Institute of Mental Health (NIMH)
- Condition
- Bipolarity
CompletedNCT06273774
This study exists to better understand the safety of the medication Elpipodect and how manageable it feels in practice. For people living with Bipolarity, that matters because care needs to work in daily life, not just in theory.
BipolarityOtherFrom 18 Years to 60 Years
- Countries
- United States
- Sponsor
- Merck Sharp & Dohme LLC
- Condition
- Bipolarity
CompletedNCT07548359
This study exists to explore whether psychoeducation, a guided learning and support program, could improve care and understanding. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can give earlier or clearer feedback during care.
BipolarityOtherOver 18 Years
- Countries
- Egypt
- Sponsor
- Menoufia University
- Condition
- Bipolarity
Active Not RecruitingNCT05054699
This study exists to compare options and see whether a therapy or guided support program offers something meaningfully different. Researchers are trying to understand whether a therapy or guided support program can improve attention, thinking, or day-to-day functioning.
DepressionOtherFrom 18 Years to 65 Years
- Countries
- Brazil
- Sponsor
- University of Sao Paulo
- Condition
- Depression
Not Yet RecruitingNCT07534475
This study exists to see whether a therapy or guided support program can make care clearer and more responsive. Researchers are trying to understand whether a therapy or guided support program can give earlier or clearer feedback during care.
DepressionOtherFrom 18 Years to 65 Years
- Countries
- Turkey
- Sponsor
- Medipol University
- Condition
- Depression
RecruitingNCT07540338
This study exists to compare options and see whether blood tests and biological markers offers something meaningfully different. Researchers are trying to understand how people respond to blood tests and biological markers in practice and what may need to be adjusted.
BipolarityOtherFrom 18 Years to 65 Years
- Countries
- United States
- Sponsor
- Alzamend Neuro, Inc.
- Condition
- Bipolarity
Not Yet RecruitingNCT07506070
This study exists to see whether a therapy or guided support program is workable and worth testing more broadly. Researchers are trying to understand whether a therapy or guided support program can improve attention, thinking, or day-to-day functioning.
DepressionOtherFrom 18 Years to 60 Years
- Countries
- Global
- Sponsor
- The Royal Ottawa Mental Health Centre
- Condition
- Depression
Not Yet RecruitingNCT07528638
This study exists to see whether symptom tracking and monitoring can make care clearer and more responsive. Researchers are trying to understand whether symptom tracking and monitoring can give earlier or clearer feedback during care.
BipolarityOtherFrom 18 Years to 70 Years
- Countries
- United States
- Sponsor
- University of Cincinnati
- Condition
- Bipolarity
CompletedNCT05317481
This study exists to understand how psychoeducation, a guided learning and support program, holds up over time after the earliest research stage. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can improve sleep, daily rhythms, and longer-term stability.
DepressionOtherFrom 16 Years to 29 Years
- Countries
- United States
- Sponsor
- Yale University
- Condition
- Depression
Active Not RecruitingNCT03349528
This study exists to compare options and see whether this type of care offers something meaningfully different. Researchers are trying to understand whether this type of care can better prevent setbacks and support longer-term stability.
DepressionOtherFrom 18 Years to 65 Years
- Countries
- United States
- Sponsor
- Sheppard Pratt Health System
- Condition
- Depression
CompletedNCT04133233
This study exists to explore whether a therapy or guided support program could improve care and understanding. Researchers are trying to understand whether a therapy or guided support program can better prevent setbacks and support longer-term stability.
DepressionOtherFrom 18 Years to 65 Years
- Countries
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
- Condition
- Depression
CompletedNCT01470781
This study exists to compare options and see whether brain scans or other body measurements offers something meaningfully different. Researchers are trying to understand whether brain scans or other body measurements can improve attention, thinking, or day-to-day functioning.
BipolarityOtherFrom 18 Years to 50 Years
- Countries
- United States
- Sponsor
- Mclean Hospital
- Condition
- Bipolarity
Not Yet RecruitingNCT07510646
This study exists to see whether a therapy or guided support program can play a useful role in care. Researchers are trying to understand whether a therapy or guided support program can better support energy, concentration, and everyday functioning.
DepressionOtherOver 18 Years
- Countries
- Canada
- Sponsor
- Vielight Inc.
- Condition
- Depression
Not Yet RecruitingNCT07503275
This study exists to see whether the medication Inhibitory can play a useful role in care. Researchers are trying to understand whether the medication Inhibitory can improve attention, thinking, or day-to-day functioning.
DepressionOtherFrom 18 Years to 65 Years
- Countries
- France
- Sponsor
- CHU de Reims
- Condition
- Depression
CompletedNCT06429722
This study exists to understand how this type of care holds up over time after the earliest research stage. Researchers are trying to understand whether this type of care can give earlier or clearer feedback during care.
DepressionOtherFrom 18 Years to 65 Years
- Countries
- United States
- Sponsor
- Neumora Therapeutics, Inc.
- Condition
- Depression
TerminatedNCT05724953
This study exists to see whether psychoeducation, a guided learning and support program, is workable and worth testing more broadly. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can make support easier to access outside standard clinic visits.
DepressionOtherOver 18 Years
- Countries
- United States
- Sponsor
- VA Office of Research and Development
- Condition
- Depression
CompletedNCT04298450
This study exists to see whether psychoeducation, a guided learning and support program, can play a useful role in care. Researchers are trying to understand whether psychoeducation, a guided learning and support program, can work better when mental health difficulties overlap with substance use.
SchizophreniaOtherFrom 16 Years to 29 Years
- Countries
- Canada
- Sponsor
- Centre for Addiction and Mental Health
- Condition
- Schizophrenia