Get research updatesDepression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.
Deep Brain Stimulation (DBS) Therapy for Treatment Resistant
This study is no longer accepting new participants.
In HoustonThis study has finished and is no longer accepting participants.
In San Diego
Does Modulation of Glutamate Transmission in the Brain Using a Sub-anaesthetic Dose of Ketamine Affect Autobiographical Memory, Emotional Processing and Decision-making in Treatment-resistant Depression?
Current recruitment status is unconfirmed.
In OxfordIntegrated Internet-Based Cognitive Behavioural Therapy (i-CBT) and Intravenous Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
This study is no longer accepting new participants.
In TorontoLow-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression: a Randomized, Double-blind Placebo-control Study
This study has finished and is no longer accepting participants.
In TaipeiOptimized Multichannel tDCS Protocol vs Conventional and Sham tDCS for Clinical Use in Patients With Major Depressive Disorder
This study has finished and is no longer accepting participants.
In ZanjanrTMS Intervention for DMPFC Treatment of Treatment-Resistant Depression Under the Guidance of Personalized Brain Functional Area Dissection (pBFS) Technology
Current recruitment status is unconfirmed.
Multiple locations, including HebeiEffects of Psilocybin With Psychological Support on Anhedonia in Treatment-resistant Depression: a Randomized Controlled Pilot Trial
This study has finished and is no longer accepting participants.
In AuroraPsilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: A Randomized Phase II Clinical Trial Comparing One Versus Two Psychedelic Doses of Psilocybin (PSI-1V2)
This study is no longer accepting new participants.
In Toronto
The effect of a mental health promotion program, called Positive Thinking Skills, on depressive and anxiety symptomatology, attribution style, and social and emotional functioning in children aged 8 to 9 years of age in a rural setting.
A randomised control trial of the effect of digital memory flexibility training (MemFlex) on depressive symptoms in young people
This study isn't recruiting yet.
In AustraliaBehavioural Activation for depressive symptoms in young people with emerging or early psychosis: a pilot study protocol
This study isn't recruiting yet.
In AustraliaWe gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.