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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,381-1,392 of 7,264
Drug study icon
TerminatedNCT06514742

Aticaprant 10 mg for depression

What is this study about?

This study evaluates the safety and effectiveness of Aticaprant for people with depression.

This study ended early.

Multiple locations, including Huntsville
DepressionMedication studyAges 18–64
Countries
United States, Belgium, Brazil, + 6 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT05550532

Aticaprant 10 Milligrams (mg) for Depression

What is this study about?

This study evaluated the safety and effectiveness of Aticaprant for people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–74
Countries
United States, France, Canada, + 11 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
TerminatedNCT06635135

Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms for depression

Official study title

A Randomized, Double-blind, Multicenter, Placebo-controlled Study of Adjunctive Aticaprant Plus an Antidepressant for Relapse Prevention in Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia

This study ended early.

Multiple locations, including Little Rock
DepressionMedication studyAges 18–64
Countries
United States, France, Belgium, + 10 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
TerminatedNCT00637494

Mifepristone for depression

What is this study about?

This study evaluates the safety and effectiveness of mifepristone for people with depression.

This study ended early.

Multiple locations, including Little Rock
Depression, SchizophreniaMedication studyAges 22+
Countries
United States
Sponsor
Corcept Therapeutics
Drug study icon
CompletedNCT07212946

Ayahuasca and Esketamine for Major Depression

Official study title

Four Doses of Ayahuasca or Esketamine in Major Depressive Disorder: a Double-blind Randomized Trial

This study has finished and is no longer accepting participants.

In Ribeirão Preto
DepressionMedication studyAges 18–65
Countries
Brazil
Sponsor
University of Sao Paulo
Behavioral study icon
RecruitingACTRN12625000108415

Evaluating the acceptability of a therapist-assisted, online parenting program (‘PiP-TEx’) to support parents of adolescents who are experiencing anxious and/or depressive symptoms following a traumatic experience.

Official study title

An open-label, uncontrolled acceptability trial of a therapist-assisted, online parenting program (‘PiP-Trauma Experience’) to support parents of adolescents who are experiencing anxious and/or depressive symptoms following a traumatic event.

In Australia
DepressionInterventional studyAges 18+
Countries
Australia
Sponsor
Monash University
Drug study icon
RecruitingACTRN12624000017527

MELODY study: A 12-week controlled study of adjunctive melatonin or digital cognitive behavioural therapy for insomnia, or placebo to improve depressive symptoms in young adults with mood disorders

Official study title

MELODY Trial: A 12-week randomised controlled trial of adjunctive melatonin or digital cognitive behavioural therapy for insomnia, or placebo to improve depressive symptoms in young adults with mood disorders

In Camperdown
Depression, BipolarityInterventional studyAges 18–30
Countries
Australia
Sponsor
The University of Sydney
Behavioral study icon
RecruitingACTRN12614000979651

Reducing the impact of aphasia in stroke patients and their caregivers a year post onset via a brief early intervention: a cluster control study of the Aphasia Action Success Knowledge (ASK) program.

Official study title

Reducing the psychosocial impact of aphasia on mood and quality of life in people with aphasia and the impact of caregiving in family members through the Aphasia Action Success Knowledge (Aphasia ASK) program: study protocol for a randomized controlled trial

In Australia
DepressionInterventional studyAges 18+
Countries
Australia
Sponsor
The University Of Queensland
Device study icon
TerminatedACTRN12618001953224

Magnetic Stimulation for treatment-resistant depression

Official study title

A New Zealand Neuroimaging Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment-Resistant Depression as assessed by the Montgomery–Åsberg Depression Rating Scale.

This study ended early.

In New Zealand
DepressionInterventional studyAges 18+
Countries
New Zealand
Sponsor
The university of Auckland

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.