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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,405-1,416 of 7,264
Drug study icon
CompletedNCT05624268

Efficacy, Safety, and Tolerability of COMP360 in people with TRD

Official study title

A Phase III, Multicentre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Treatment-resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Tuscon
DepressionMedication studyAges 18+
Countries
United States
Sponsor
COMPASS Pathways
Drug study icon
Active Not RecruitingNCT05711940

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in people with TRD

Official study title

A Phase III, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With Treatment-resistant Depression

This study is no longer accepting new participants.

Multiple locations, including Gilbert
DepressionMedication studyAges 18+
Countries
United States, France, Canada, + 9 others
Sponsor
COMPASS Pathways
Device study icon
CompletedNCT01331330

European Deep Brain Stimulation (DBS) Depression Study

Official study title

A Clinical Evaluation of Different Device Parameters for the Management of Patients With Treatment Resistant Major Depressive Disorder, Single or Recurrent Episode, With Deep Brain Stimulation

This study has finished and is no longer accepting participants.

Multiple locations, including Nice
DepressionDevice studyAges 21–70
Countries
France, United Kingdom, Israel
Sponsor
Abbott Medical Devices
Drug study icon
CompletedNCT06965569

Multiple Ascending Dose Phase 1 Study of ALA-3000

What is this study about?

This study evaluated the safety and effectiveness of ALA-3000 for people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Little Rock
DepressionMedication studyAges 18–65
Countries
United States
Sponsor
Alar Pharmaceuticals Inc.
Drug study icon
Active Not RecruitingNCT06303739

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

Official study title

Induction Protocol for Psilocybin-Assisted Therapy in Treatment-Resistant Depression (TRD): A Pilot Study

This study is no longer accepting new participants.

In Chapel Hill
DepressionMedication studyAges 18–70
Countries
United States
Sponsor
University of North Carolina, Chapel Hill
Drug study icon
CompletedNCT04680910

Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) I

Official study title

Precision Targeting of Propofol-induced Electroencephalographic Slow Waves: a Novel Phase I Paradigm for Treatment-resistant Major Depressive Disorder

This study has finished and is no longer accepting participants.

In St Louis
DepressionMedication studyAges 60+
Countries
United States
Sponsor
Washington University School of Medicine
Drug study icon
CompletedNCT05454410

MIJ821 for treatment-resistant depression

Official study title

A Randomized, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Single Subcutaneous MIJ821 Injection in Addition to Standard of Care in Participants With Treatment-resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–65
Countries
United States, Japan, Poland, + 1 other
Sponsor
Novartis Pharmaceuticals
Drug study icon
CompletedNCT03586427

Zelquistinel in the Treatment of Major Depressive Disorder

What is this study about?

Researchers compared AGN-241751 and placebo to find out how the approaches affected depression symptoms in adults with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Fayetteville
DepressionMedication studyAges 18–65
Countries
United States
Sponsor
Syndeio Biosciences, Inc

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.