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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,633-1,644 of 7,264
Drug study icon
CompletedEUCTR 2009-011409-17

Randomized evaluation of the effectiveness of lithium in subjects with treatment-resistant depression and suicide risk. An independent, pragmatic, multicentre, parallel-group, superiority trial.

This study has finished and is no longer accepting participants.

Historical country statuses are shown below. They describe the trial's progress and do not confirm open recruitment.

In Italy
Depression, SuicidalityHistorical research record
Countries
Italy
Sponsor
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
Drug study icon
Not recruitingEUCTR 2019-001023-13

PAX-D: Randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression

This study isn't currently recruiting.

Recruitment status comes from the linked ISRCTN record. Both registries list the identifiers for the same study.

In United Kingdom
DepressionHistorical research record
Countries
United Kingdom
Sponsor
University of Oxford / Clinical Trials and Research Governance
Drug study icon
CompletedNCT06524830

VLS-01 Buccal Film, Compared to Placebo for treatment-resistant depression

Official study title

A Phase 2, Multicenter, Double-blind, Randomized, Placebo-controlled Trial to Assess the Efficacy, Safety, and Tolerability of Repeated Doses of VLS-01 Buccal Film in Participants With Treatment Resistant Depression

This study has finished and is no longer accepting participants.

Multiple locations, including Tucson
DepressionMedication studyAges 18–65
Countries
United States, Australia, Canada, + 1 other
Sponsor
atai Therapeutics, Inc.
Drug study icon
CompletedNCT02417064

Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant for treatment-resistant depression

What is this study about?

This study evaluated the safety and effectiveness of Esketamine for people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–64
Countries
United States, France, Canada, + 6 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT02418585

Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant for treatment-resistant depression

What is this study about?

This study evaluated the safety and effectiveness of Esketamine for people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 18–64
Countries
United States, Czechia, Germany, + 2 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT05800860

A study of GH001 in people with Treatment-resistant Depression

What is this study about?

This study evaluated the safety and effectiveness of GH001 for people with depression.

This study has finished and is no longer accepting participants.

Multiple locations, including Pilsen
DepressionMedication studyAges 18–64
Countries
Czechia, Germany, Ireland, + 3 others
Sponsor
GH Research Ireland Limited

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.