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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 1,957-1,968 of 7,264
Drug study icon
Recruitment unclearEUCTR 2015-003578-34

An Open-label Long-term Extension Safety Study of Intranasal Esketamine in Treatment resistant Depression

Current recruitment status is unconfirmed.

This older record does not confirm current recruitment. No matching public CTIS record was confirmed using this identifier. Ask the research team for an up-to-date source.

In Austria
DepressionHistorical research record
Countries
United Kingdom, Belgium, Austria, + 10 others
Sponsor
Janssen-Cilag International NV
Drug study icon
CompletedNCT07096791

KH607 Tablets for depression

Official study title

A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of KH607 in the Treatment of Adult Female Participants With Postpartum Depressive Disorder

This study has finished and is no longer accepting participants.

In Beijing
DepressionMedication studyAges 18–45
Countries
China
Sponsor
Chengdu Kanghong Pharmaceutical Group Co., Ltd.
Drug study icon
CompletedNCT01998958

Safety and Efficacy of Intranasal Esketamine for treatment-resistant depression

Official study title

A Double-Blind, Doubly-Randomized, Placebo-Controlled Study of Intranasal Esketamine in an Adaptive Treatment Protocol to Assess Safety and Efficacy in Treatment-Resistant Depression (SYNAPSE)

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 20–64
Countries
United States, Belgium, Japan
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT02577250

Ketamine Infusions for PTSD and Treatment-Resistant Depression

Official study title

Efficacy and Safety of Repeated Intravenous Subanesthetic Ketamine Infusions Among Veterans With Treatment Resistant Depression Comorbid With Chronic Post-Traumatic Stress Disorder: A Proof-of-concept Study

This study has finished and is no longer accepting participants.

In Minneapolis
Depression, PTSDMedication studyAges 18–75
Countries
United States
Sponsor
Minneapolis Veterans Affairs Medical Center
Device study icon
CompletedNCT01596608

Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and OCD

Official study title

Efficacy and Tolerability of Magnetic Seizure Therapy (MST) as an Alternative to Electroconvulsive Therapy (ECT) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder

This study has finished and is no longer accepting participants.

In Toronto
Depression, Schizophrenia, ...Device studyAges 18–85
Countries
Canada
Sponsor
Centre for Addiction and Mental Health (Hospital / academic medical center)
Other study type icon
CompletedACTRN12605000183684

A correspondence-based program to prevent relapse of depression.

Official study title

Detection of relapse risk and improvement of health risk behaviours in people with depression: Randomised controlled trial of correspondence-based assistance to general practitioners.

This study has finished and is no longer accepting participants.

Location not clearly listed
DepressionInterventional studyAges 18+
Countries
Sponsor
Professor David J. Kavanagh
Behavioral study icon
CompletedACTRN12613000502730

A controlled study comparing Internet based cognitive behavioural therapy (CBT) versus a cognitive behavioural therapy (CBT) self help book versus a meditation self help book versus a waitlist control condition for adults with depression on severity of symptoms and depression.

Official study title

A randomised controlled trial comparing an Internet based Cognitive Behavioural Therapy (CBT) treatment versus a Cognitive Behavioural Therapy (CBT) self help book versus a meditation self help book versus a waitlist control condition for Adults with Depression on severity of symptoms of depression.

This study has finished and is no longer accepting participants.

In Darlinghurst
DepressionInterventional studyAges 18+
Countries
Australia
Sponsor
St Vincent's Hospital, Sydney
Behavioral study icon
CompletedACTRN12615000927527

A controlled study comparing internet-delivered Cognitive Behavioural Therapy (iCBT), internet-delivered Mindfulness-Enhanced Cognitive Behavioural Therapy, internet-delivered Mindfulness Skills Training versus usual care for adults with depression and/or anxiety.

Official study title

A randomised controlled trial comparing internet-delivered Cognitive Behavioural Therapy (iCBT), internet-delivered Mindfulness-Enhanced Cognitive Behavioural Therapy, internet-delivered Mindfulness Skills Training versus usual care for adults with depression and/or anxiety on the severity of symptoms of depression and anxiety.

This study has finished and is no longer accepting participants.

In Darlinghurst
Depression, Anxiety, ...Interventional studyAges 18+
Countries
Australia
Sponsor
St Vincent's Hospital Sydney
Other study type icon
CompletedACTRN12611000040965

Association of signal transduction pathway genes and their interaction with environment factors with antidepressant treatment response

Official study title

There is an association of signal transduction pathway genes and their interaction with environment factors with antidepressant treatment response in patients of major depressive disorder.

This study has finished and is no longer accepting participants.

In China
DepressionObservational studyAges 18–60
Countries
China
Sponsor
Zhijun Zhang

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.