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Depression studies

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Depression

Depression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.

7264studies shown
Showing 2,461-2,472 of 7,264
Drug study icon
CompletedNCT03374475

A Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in people with Major Depressive Disorder

Official study title

An Exploratory, Multicenter, Placebo-controlled, Randomized, Double-blind Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in Subjects With Major Depressive Disorder

This study has finished and is no longer accepting participants.

Multiple locations, including San Diego
DepressionMedication studyAges 18–55
Countries
United States, United Kingdom, Belgium, + 2 others
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT02902601

A Study to Investigate the Safety, Tolerability, and Pharmacodynamics of JNJ-54175446 in people with Major Depressive Disorder

Official study title

A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Investigate the Safety, Tolerability, and Pharmacodynamics of JNJ-54175446 in Subjects With Major Depressive Disorder

This study has finished and is no longer accepting participants.

Multiple locations, including Berlin
DepressionMedication studyAges 18–64
Countries
Germany, Netherlands
Sponsor
Janssen Research & Development, LLC
Drug study icon
CompletedNCT06280235

A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine

Official study title

A Phase II, 6-week, Multicenter, Randomized, Double Blind (Patient and Investigator) or Masked, Placebo Controlled, Dose-finding Trial to Evaluate the Efficacy, Tolerability, and Safety of Different Doses of Oral BI 1569912 as Adjunctive Therapy in MD

This study has finished and is no longer accepting participants.

Multiple locations, including Tucson
DepressionMedication studyAges 18–65
Countries
United States, Belgium, Bulgaria, + 4 others
Sponsor
Boehringer Ingelheim
Drug study icon
CompletedNCT02473289

Sirukumab for depression

Official study title

A Double-Blind, Placebo-Controlled, Multicenter Study of Sirukumab as Adjunctive Treatment to a Monoaminergic Antidepressant in Adults With Major Depressive Disorder

This study has finished and is no longer accepting participants.

Multiple locations, including Birmingham
DepressionMedication studyAges 21–64
Countries
United States, Canada, United Kingdom, + 2 others
Sponsor
Janssen Research & Development, LLC
Other study type icon
CompletedNCT00576095

Clinical and Biological Characteristics of Psychotic Depression

Official study title

Hypothalamic-Pituitary-Adrenal (HPA)/ Dopamine Axis in Psychotic Depression

This study has finished and is no longer accepting participants.

In Stanford
Depression, SchizophreniaObservational studyAges 18–85
Countries
United States
Sponsor
Stanford University
Device study icon
Active Not RecruitingNCT04684706

Compressed Intermittent Theta Burst Stimulation

Official study title

A Within Study on the Effects of L-dlPFC Activation Through iTBS in Refractory Depression

This study is no longer accepting new participants.

Multiple locations, including La Jolla
DepressionDevice studyAges 18–70
Countries
United States
Sponsor
University of Pennsylvania
Drug study icon
CompletedNCT05710237

Does Psilocybin Require Psychedelic Effects to Treat Depression?

Official study title

Does Psilocybin Require Psychedelic Effects to Treat Depression? A 4-Week, Double-Blind, Proof-of-Concept Randomized Controlled Trial

This study has finished and is no longer accepting participants.

In Toronto
DepressionMedication studyAges 18–65
Countries
Canada
Sponsor
Centre for Addiction and Mental Health (Hospital / academic medical center)

Registry coverage

We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.