Get research updatesDepression involves persistent low mood or loss of interest, often with tiredness and changes in sleep or appetite.
Differential Treatment Effectiveness in Patients with the melancholic sub-type of depression
Amongst depressed adolescents attending a rural Child and Adolescent Mental Health Service, does Interpersonal Psychotherapy, compared to Treatment as Usual, improve clinical care? An implementation feasibility study
Double-Blind Randomised Investigation of Bazedoxifene and Conjugated Estrogen for Depression in Menopausal Women
A randomised controlled trial evaluating the 'Happiness, Understanding, Giving and Sharing' (HUGS) program for improving mother-infant relationships among women with postnatal depression and their infants
Randomized controlled trial of methylphenidate (either as a monotherapy or an adjunct treatment) compared to an antidepressant group (dual action or tricyclic antidepressants) for patients with treatment-resistant melancholic depression to see if effective in improvement in depression ratings and remission over an 8-week period.
This study evaluates the effectiveness of cognitive behavioural therapy for people with depression.
Efficacy of the SMS4dads text messaging program in reducing depression and anxiety in new fathers, a randomised controlled trial.
A study to evaluate the effects of Interferon-alpha treatment on changes in facial recognition tasks in hepatitis C patients
Evaluating an online program for carers of people with symptoms of depression or anxiety: a randomised controlled trial
An open-label, uncontrolled acceptability trial of a self-guided, online parenting program (‘PiP-Ed’) to support parents of adolescents who refuse school in the context of anxiety and/or depression.
An open-label, uncontrolled trial to evaluate the real-world uptake, engagement and effects of the Partners in Parenting Kids (PiP Kids) online program, targeting anxiety and depression in children, in partnership with the Raising Children Network
Evaluate the efficacy of an internet-based psychological program for people who are concurrently depressed and drinking alcohol at harmful levels.
We gather information about mental health clinical trials from the public registries we index. Coverage is still expanding, so some studies may not appear yet.